WordNet

in or near a center or constituting a center; the inner area; "a central position"
a workplace that serves as a telecommunications facility where lines from telephones can be connected together to permit communication (同)telephone exchange, exchange
use recreational drugs (同)do drugs
administer a drug to; "They drugged the kidnapped tourist" (同)dose
a substance that is used as a medicine or narcotic
a medicine used to relieve pain (同)anodyne, painkiller, pain pill
capable of relieving pain; "the anodyne properties of certain drugs"; "an analgesic effect" (同)analgetic, anodyne

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 慢性疼痛の治療の概要 overview of the treatment of chronic pain
2. 癌疼痛のマネージメント：鎮痛補助剤（鎮痛剤） cancer pain management adjuvant analgesics coanalgesics
3. 非選択性非ステロイド性抗炎症剤（NSAIDs）：副作用の概要 nonselective nsaids overview of adverse effects
4. 処方剤の誤用：疫学、予防、同定、およびマネージメント prescription drug misuse epidemiology prevention identification and management
5. 高齢患者に対する麻酔 anesthesia for the older adult patient

Transepithelial Corneal Cross-Linking With Vitamin E-Enhanced Riboflavin Solution and Abbreviated, Low-Dose UV-A: 24-Month Clinical Outcomes.

Caruso C1, Ostacolo C, Epstein RL, Barbaro G, Troisi S, Capobianco D.
Cornea.Cornea.2016 Feb;35(2):145-50. doi: 10.1097/ICO.0000000000000699.
PURPOSE: To report the clinical outcomes with 24-month follow-up of transepithelial cross-linking using a combination of a D-alpha-tocopheryl polyethylene-glycol 1000 succinate (vitamin E-TPGS)-enhanced riboflavin solution and abbreviated low fluence UV-A treatment.METHODS: In a nonrandomized clinic
PMID 26606293

Seasonal occurrence, removal, mass loading and environmental risk assessment of 55 pharmaceuticals and personal care products in a municipal wastewater treatment plant in Central Greece.

Papageorgiou M1, Kosma C2, Lambropoulou D3.
The Science of the total environment.Sci Total Environ.2016 Feb 1;543(Pt A):547-69. doi: 10.1016/j.scitotenv.2015.11.047. Epub 2015 Nov 22.
A comprehensive study, which contains the seasonal occurrence, removal, mass loading and environmental risk assessment of 55 multi-class pharmaceuticals and personal care products (PPCPs), took place in the wastewater treatment plant (WWTP) of Volos, Greece. A one year monitoring study was performed
PMID 26613513

Stein C1,2.
Annual review of medicine.Annu Rev Med.2016 Jan 14;67:433-51. doi: 10.1146/annurev-med-062613-093100. Epub 2015 Aug 26.
Opioids are the oldest and most potent drugs for the treatment of severe pain. Their clinical application is undisputed in acute (e.g., postoperative) and cancer pain, but their long-term use in chronic pain has met increasing scrutiny. This article reviews mechanisms underlying opioid analgesia and
PMID 26332001

A Novel Model of Pain Sensation Using Superfused Gastrosplenic Omentum Preparation of Anesthetized Rats

Yang Shi-Jie,Katori Makoto,Majima Masataka
Journal of pharmacological sciences 106(2), 249-256, 2008-02-20
… Modification of the RHR was tested by topical (in the chamber) or intravenous administration of drugs. … Topical administration of a non-acidic analgesic, mepirizole, inhibited the RHR by topical BK by only 20%, but intravenous mepirizole inhibited topical BK by 96.2%, indicating its major central action. …
NAID 10024318339

嵜山陽二郎,小宮山靖,塚田秀夫
藥學雜誌 127(12), 2079-2084, 2007-12-01
… Animal pain testing is essential for the development of new analgesic drugs, where appropriate data analyses as well as appropriate multi-factorial design of experiments are necessary to obtain meaningful results in an efficient fashion. … This method, together with a graphical approach, may prove to be valuable for assessing the sensitivity and reproducibility of an experimental condition, as well as the pharmacological effects of analgesic drugs. …
NAID 110006546584

General Pharmacology of DW-286a, a New Fluoronaphthyridone Antibiotic : Effects on Central Nervous, Cardiovascular, and Respiratory Systems (Pharmacology)

Kim Eun-Joo,Shin Won-Ho
Biological & pharmaceutical bulletin 27(5), 641-646, 2004-05-01
… Its effect on the central nervous system, general behavior, and cardiovascular, respiratory, and other organ systems were studied. … The doses given were 30, 50, 100, 150, 300, and 1000 mg/kg and drugs were administered orally. … DW-286a did not show any effects on general behavior, motor coordination, analgesic action, seizure and mortality, blood pressure and heart rate, contractile response of isolated guinea pig ileums, and renal function. …
NAID 110003608823