WordNet

the act of making up your mind about something; "the burden of decision was his"; "he drew his conclusions quickly" (同)determination, conclusion
a position or opinion or judgment reached after consideration; "a decision unfavorable to the opposition"; "his conclusion took the evidence into account"; "satisfied with the panels determination" (同)determination, conclusion
(boxing) a victory won on points when no knockout has occurred; "had little trouble in taking a unanimous decision over his opponent"
the outcome of a game or contest; "the team dropped three decisions in a row"
small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
having an (over)abundance of flesh; "he hadnt remembered how fat she was"
a soft greasy substance occurring in organic tissue and consisting of a mixture of lipids (mostly triglycerides); "pizza has too much fat"
marked by great fruitfulness; "fertile farmland"; "a fat land"; "a productive vineyard"; "rich soil" (同)fertile, productive, rich
lucrative; "a juicy contract"; "a nice fat job" (同)juicy
having a relatively large diameter; "a fat rope"
the syllable naming the fourth (subdominant) note of the diatonic scale in solmization

PrepTutorEJDIC

〈C〉(問題・疑義などの)『決定』,解決;結論《+『of』+『名』》 / 〈U〉『決心』,決断 / 〈C〉(法廷での)『判決』;判定 / 〈U〉決断力
(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
『脂肪』,脂肪分 / (動物の)あぶら身 / (料理用の)油,ヘット / 肥満,太り過ぎ / 『太った』,肥満した / 『脂肪の多い』 / たっぷりとはいった,分厚い / もうかる / (土地が)肥えた / …‘を'太らせる / ふとる,肥える
〈U〉『運命』,宿命 / 〈U〉(運命として定められた)最期,破滅,(特に)死 / 《the Fates》(ギリシア・ローマ神話の)運命の三女神(Clotho,Lachesis,Atropes) / …‘を'運命づける
ファ(全音階の第4音)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 再発性または難治性のびまん性大細胞型B細胞リンパ腫の治療 treatment of relapsed or refractory diffuse large b cell lymphoma
2. 進行腎細胞癌に対する抗血管新生療法および分子標的療法 anti angiogenic and molecularly targeted therapy for advanced renal cell carcinoma
3. 自家造血幹細胞移植の適格性判定 determining eligibility for autologous hematopoietic cell transplantation
4. 同種造血細胞移植の適応判定 determining eligibility for allogeneic hematopoietic cell transplantation
5. 末梢性T細胞リンパ腫の初期治療 initial treatment of peripheral t cell lymphoma

English Journal

MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis.

Xu J, Wang Y, Tan X, Jing H.SourceCollege of Bioengineering; Henan Universitfy of Technology; Zhengzhou, China.
Autophagy.Autophagy.2012 Jun 1;8(6). [Epub ahead of print]
Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved self-degradative process, which involves the regular turnover of cellular components via sequestering damaged macromolecules and transporting them for lysosomal degradation. In the past few years, the scientific commu
PMID 22441107

Mapping mouse hemangioblast maturation from headfold stages.

Rhee JM, Iannaccone PM.AbstractThe mouse posterior primitive streak at neural plate/headfold stages (NP/HF, ~7.5dpc-8dpc) represents an optimal window from which hemangioblasts can be isolated. We performed immunohistochemistry on this domain using established monoclonal antibodies for proteins that affect blood and endothelial fates. We demonstrate that HoxB4 and GATA1 are the first set of markers that segregate independently to endothelial or blood populations during NP/HF stages of mouse embryonic development. In a subset of cells, both proteins are co-expressed and immunoreactivities appear mutually excluded within nuclear spaces. We searched for this particular state at later sites of hematopoietic stem cell emergence, viz., the aorta-gonad-mesonephros (AGM) and the fetal liver at 10.5-11.5dpc, and found that only a rare number of cells displayed this character. Based on this spatial-temporal argument, we propose that the earliest blood progenitors emerge either directly from the epiblast or through segregation within the allantoic core domain (ACD) through reduction of cell adhesion and pSmad1/5 nuclear signaling, followed by a stochastic decision toward a blood or endothelial fate that involves GATA1 and HoxB4, respectively. A third form in which binding distributions are balanced may represent a common condition shared by hemangioblasts and HSCs. We developed a heuristic model of hemangioblast maturation, in part, to be explicit about our assumptions.
Developmental biology.Dev Biol.2012 May 1;365(1):1-13. Epub 2012 Feb 24.
The mouse posterior primitive streak at neural plate/headfold stages (NP/HF, ~7.5dpc-8dpc) represents an optimal window from which hemangioblasts can be isolated. We performed immunohistochemistry on this domain using established monoclonal antibodies for proteins that affect blood and endothelial f
PMID 22426104

Japanese Journal

MAP kinase cascades regulating axon regeneration in C. elegans

, ,
Proceedings of the Japan Academy, Series B 91(3), 63-75, 2015
… elegans have shed light on the physiological roles of MAPK cascades in the control of cell fate decision, neuronal function and immunity. …
NAID 130004802307

A Novel ATM/TP53/p21-Mediated Checkpoint Only Activated by Chronic γ-Irradiation

Cao Lili,Kawai Hidehiko,Sasatani Megumi,Iizuka Daisuke,Masuda Yuji,Inaba Toshiya,Suzuki Keiji,Ootsuyama Akira,Umata Toshiyuki,Kamiya Kenji,Suzuki Fumio
PLoS ONE 9(8), e104279, 2014-08-05
… Different levels or types of DNA damage activate distinct signaling pathways that elicit various cellular responses, including cell-cycle arrest, DNA repair, senescence, and apoptosis. … Whereas a range of DNA-damage responses have been characterized, mechanisms underlying subsequent cell-fate decision remain elusive. …
NAID 120005477031