WordNet

clearly defined or formulated; "the plain and unequivocal language of the laws"- R.B.Taney (同)unequivocal
supplying or being a final or conclusive settlement; "a definitive verdict"; "a determinate answer to the problem" (同)determinate
of or involving or characteristic of critics or criticism; "critical acclaim"
forming or having the nature of a turning point or crisis; "a critical point in the campaign"; "the critical test" (同)decisive
urgently needed; absolutely necessary; "a critical element of the plan"; "critical medical supplies"; "vital for a healthy society"; "of vital interest" (同)vital
at or of a point at which a property or phenomenon suffers an abrupt change especially having enough mass to sustain a chain reaction; "a critical temperature of water is 100 degrees C--its boiling point at standard atmospheric pressure"; "critical mass"; "go critical"
being in or verging on a state of crisis or emergency; "a critical shortage of food"; "a critical illness"; "an illness at the critical stage"
characterized by careful evaluation and judgment; "a critical reading"; "a critical dissertation"; "a critical analysis of Melvilles writings"
marked by a tendency to find and call attention to errors and flaws; "a critical attitude"
fix in scope; fix the boundaries of; "the tree determines the border of the property"
find out, learn, or determine with certainty, usually by making an inquiry or other effort; "I want to see whether she speaks French"; "See whether it works"; "find out if he speaks Russian"; "Check whether the train leaves on time" (同)check, find_out, see, ascertain, watch, learn
establish after a calculation, investigation, experiment, survey, or study; "find the product of two numbers"; "The physicist who found the elusive particle won the Nobel Prize" (同)find, find_out, ascertain
fix conclusively or authoritatively; "set the rules" (同)set
shape or influence; give direction to; "experience often determines ability"; "mold public opinion" (同)shape, mold, influence, regulate
influence or determine; "The vote in New Hampshire often decides the outcome of the Presidential election"
reach, make, or come to a decision about something; "We finally decided after lengthy deliberations" (同)make up one''s mind, determine
bring to an end; settle conclusively; "The case was decided"; "The judge decided the case in favor of the plaintiff"; "The father adjudicated when the sons were quarreling over their inheritance" (同)settle, resolve, adjudicate
cause to decide; "This new development finally decided me!"
the act of making up your mind about something; "the burden of decision was his"; "he drew his conclusions quickly" (同)determination, conclusion
a position or opinion or judgment reached after consideration; "a decision unfavorable to the opposition"; "his conclusion took the evidence into account"; "satisfied with the panels determination" (同)determination, conclusion
(boxing) a victory won on points when no knockout has occurred; "had little trouble in taking a unanimous decision over his opponent"
the outcome of a game or contest; "the team dropped three decisions in a row"
conclusive in a process or progression; "the final answer"; "a last resort"; "the net result" (同)last, net
the final match between the winners of all previous matches in an elimination tournament
not to be altered or undone; "the judges decision is final"; "the arbiter will have the last say" (同)last

PrepTutorEJDIC

決定的な,最終的な(final)
『評論の』,批評の / 批判的な,物を見る眼のある / 『酷評的な』,あら捜しの,手きびしい / 『危機の』,危急の;(病気が)危篤の / 臨界の(温度・圧力などにより物質が急速にその状態を変える境),臨界点における
(前もって)…‘を'『決定する』,はっきりさせる / …‘を'『決心する』,決意する / 《『determine』+『名』+『to』 do》〈物事が〉(…することを)〈人〉‘に'決心させる』,決意させる / …‘を'『左右する』,決定づける / 〈数量・位置・速度など〉‘を'測定する,確認する / (…を)決心する,決定する《+『on』+『名』(do『ing』)》
〈人が〉〈論争・問題など〉'を'『解決する』 / 〈人が〉『決心する』 / 〈物事が〉…'を'決定する / 〈物事が〉〈人〉‘に'決意させる,決定させる / 『決定する』 / (…に不利な,有利な)判決を下す《+『against』(『for』,『in favor of』)+『名』》
〈C〉(問題・疑義などの)『決定』,解決;結論《+『of』+『名』》 / 〈U〉『決心』,決断 / 〈C〉(法廷での)『判決』;判定 / 〈U〉決断力
《名詞の前にのみ用いて》『最終の』,最後の / 『最終的な』,決定的な(decisive);究極の(ultimate) / 《しばしば複数形で》(競技などの)『決勝戦』 / 《米》学期末試験;《英》《複数形で》(大学などの)最終試験 / 《the ~》《話》(新聞のその日の)最終版

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/06 14:40:09」(JST)

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1. 成人における重症骨盤骨折の確実なマネージメント definitive management of severe pelvic fractures in adults
2. 進行頭頸部癌に対する根治的放射線療法：線量および分割スケジュール definitive radiotherapy for advanced head and neck cancer dose and fractionation schedule
3. エキノコックス種の生活環および疫学 life cycle and epidemiology of echinococcal species
4. Follow-up surveillance during and after treatment for prostate cancer
5. 胆道寄生虫症の内視鏡診断およびマネージメント endoscopic diagnosis and management of biliary parasitosis

English Journal

Production of mono- and di-carboxylated polyethylene glycols as a factor obstacle to the successful ozonation-assisted biodegradation of ethoxylated compounds.

Nakai S1, Okuda T2, Nishijima W3, Okada M4.
Chemosphere.Chemosphere.2015 Oct;136:153-9. doi: 10.1016/j.chemosphere.2015.04.069. Epub 2015 May 15.
Ozonation is believed to improve the biodegradability of organic compounds. In the present study, degradation of nonylphenol ethoxylates (NPEOs) was monitored in hybrid treatment systems consisting of ozonation and microbial degradation processes. We found that ozonation of NPEOs decreased, rather t
PMID 25985303

Identification of different species of Bacillus isolated from Nisargruna Biogas Plant by FTIR, UV-Vis and NIR spectroscopy.

Ghosh SB1, Bhattacharya K2, Nayak S3, Mukherjee P1, Salaskar D1, Kale SP4.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2015 Sep 5;148:420-6. doi: 10.1016/j.saa.2015.03.104. Epub 2015 Apr 3.
Definitive identification of microorganisms, including pathogenic and non-pathogenic bacteria, is extremely important for a wide variety of applications including food safety, environmental studies, bio-terrorism threats, microbial forensics, criminal investigations and above all disease diagnosis.
PMID 25930088

Maternal stress, nutrition and physical activity: Impact on immune function, CNS development and psychopathology.

Marques AH1, Bjørke-Monsen AL2, Teixeira AL3, Silverman MN4.
Brain research.Brain Res.2015 Aug 18;1617:28-46. doi: 10.1016/j.brainres.2014.10.051. Epub 2014 Nov 4.
Evidence suggests that maternal and fetal immune dysfunction may impact fetal brain development and could play a role in neurodevelopmental disorders, although the definitive pathophysiological mechanisms are still not completely understood. Stress, malnutrition and physical inactivity are three mat
PMID 25451133

Comparison of acute toxicities associated with cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy for head and neck squamous cell carcinomas: A single-institution retrospective study in Japan.

Sakashita T1, Homma A, Hatakeyama H, Furusawa J, Kano S, Mizumachi T, Iizuka S, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.
Acta oto-laryngologica.Acta Otolaryngol.2015 Aug;135(8):853-8. doi: 10.3109/00016489.2015.1030772. Epub 2015 Mar 26.
CONCLUSION: Grade ≥ 3 mucositis/stomatitis and inability to feed orally were problematic for patients undergoing cetuximab-based bioradiotherapy (BRT) as well as platinum-based chemoradiotherapy (CRT). Severe mucositis/stomatitis and radiation dermatitis should be addressed carefully in patients u
PMID 25814008

Japanese Journal

SLC25A13 Gene Analysis in Citrin Deficiency: Sixteen Novel Mutations in East Asian Patients, and the Mutation Distribution in a Large Pediatric Cohort in China

Song Yuan-Zong,Zhang Zhan-Hui,Lin Wei-Xia,Zhao Xin-Jing,Deng Mei,Ma Yan-Li,Guo Li,Chen Feng-Ping,Long Xiao-Ling,He Xiang-Ling,Sunada Yoshihide,Soneda Shun,Nakatomi Akiko,Dateki Sumito,Ngu Lock-Hock,Kobayashi Keiko,Saheki Takeyori
PLoS ONE 8(9), e74544, 2013-09-19
… analyses of SLC25A13 gene and its protein/mRNA products remain reliable tools for the definitive diagnoses of CD patients, and so far, the SLC25A13 mutation spectrum in Chinese CD patients has not been well-characterized yet.Methods and Results:By means of direct DNA sequencing, cDNA cloning and SNP analyses, 16 novel pathogenic mutations, including 9 missense, 4 nonsense, 1 splice-site, 1 deletion and 1 large transposal insertion IVS4ins6kb (GenBank accession number KF425758), were identified in CTLN2 or NICCD patients from China, Japan and Malaysia, …
NAID 120005343849

脊髄性筋萎縮症の遺伝カウンセリング

浦野真理,齋藤加代子
東京女子医科大学雑誌 83(E3), E651-E655, 2013-07-31
近年、分子遺伝学の進歩により、多くの遺伝性疾患の原因遺伝子が特定されてきた。遺伝学的検査による確定診断は、原因を特定するだけではなく、治療や予防に有用な情報が得られることにつながった。そのため、患者には適切な情報提供が必要となり、遺伝カウンセリングの重要性が増していくと考えられる。本稿では脊髄性筋萎縮症(Spinal Muscular Atrophy)の遺伝カウンセリングについて述べる。,遺伝カウ …
NAID 110009604922

α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells

Michikoshi Hiromitsu,Nakamura Takahiro,Sakai Katsuya,Suzuki Yoshinori,Adachi Eri,Matsugo Seiichi,Matsumoto Kunio
Cancer Letters 335(2), 472-478, 2013-07-28
… In the present study, we investigated the effects of α-LA on the proliferation and activation status of definitive receptor tyrosine kinases, epidermal growth factor receptor (EGFR) and Met/hepatocyte growth factor (HGF) receptor, in gefitinib-sensitive human non-small cell lung cancer cells harboring EGFRs with an activating mutation. …
NAID 120005254051

気管支原発形質細胞腫の1例

丸井努,長谷川貴昭,二村洋平,堀場あかね,石黒崇,吉田勉,澤祥幸
気管支学 : 日本気管支研究会雑誌 35(4), 409-412, 2013-07-25
背景.気管支原発髄外性形質細胞腫は稀である.今回,右下葉支に発生した髄外性形質細胞腫の1手術例を経験したので,報告する.症例. 57歳男性.狭心症の精査中の胸部CT検査で腫瘤を指摘され,精査加療目的に当科紹介された.胸部CTでは右B^9+B^<10>に1.2×0.9cmの腫瘤を認めた.気管支鏡検査ではB^9+B^<10>の入口部にポリープ状の腫瘤を認めた.気管支鏡下生検にて …
NAID 110009635593