WordNet
- limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
- control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
- limit the range or extent of; "Contact between the young was inhibited by strict social customs"
- a substance that retards or stops an activity
- any of a group of proteases that mediate apoptosis
PrepTutorEJDIC
- 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
- 抑制する人(物) / 化学反応抑制剤
UpToDate Contents
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- 1. アポトーシスと自己免疫疾患 apoptosis and autoimmune disease
- 2. 肝線維症の新しい治療法 emerging therapies for hepatic fibrosis
- 3. 複合免疫不全 combined immunodeficiencies
- 4. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
- 5. パーキンソン病の病因および発症機序 etiology and pathogenesis of parkinson disease
English Journal
- Evaluating the Effects of CDK Inhibitors in Ischemia-Reperfusion Injury Models.
- Guevara T1.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1336:111-21. doi: 10.1007/978-1-4939-2926-9_10.
- CDK inhibitors have been used to induce protection in various experimental models. Kidney ischemia-reperfusion (I/R) is a form of acute kidney injury resulting in a cascade of cellular events prompting rapid cellular damage and suppression of kidney function. I/R injury, an inevitable impairment dur
- PMID 26231712
- Inhibition of p38 MAPK activation protects cardiac mitochondria from ischemia/reperfusion injury.
- Kumphune S1, Surinkaew S, Chattipakorn SC, Chattipakorn N.
- Pharmaceutical biology.Pharm Biol.2015 Dec;53(12):1831-41. doi: 10.3109/13880209.2015.1014569. Epub 2015 Apr 16.
- CONTEXT: Cardiac cell death and fatal arrhythmias during myocardial ischemia/reperfusion (I/R) can be reduced by p38 MAPK inhibition. However, the effects of p38 MAPK inhibition on cardiac mitochondria have not been investigated.OBJECTIVE: We tested the hypothesis that p38 MAPK inhibition at differe
- PMID 25880145
- Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells.
- Munoz JL1, Walker ND2, Scotto KW3, Rameshwar P4.
- Cancer letters.Cancer Lett.2015 Oct 10;367(1):69-75. doi: 10.1016/j.canlet.2015.07.013. Epub 2015 Jul 21.
- Chemotherapeutic resistance can occur by P-glycoprotein (P-gp), a 12-transmembrane ATP-dependent drug efflux pump. Glioblastoma (GBM) has poor survival rate and uniformly acquired chemoresistance to its frontline agent, Temozolomide (TMZ). Despite much effort, overcoming TMZ resistance remains a cha
- PMID 26208431
Japanese Journal
- <no title>
- Kim Jin Woo,Gotoh Takafumi,Lim Hyoun–Sub,Song Ki Hak,Sul Chong Koo
- Journal of the Faculty of Agriculture, Kyushu University 59(2), 289-296, 2014-08-29
- … COX–2 has major roles in inflammatory reaction, and COX–2 inhibitor and genistein have a chemopreventive effect on some cancers such as colorectal, breast, and prostate cancer (PCa). … The mRNA expressions of androgen receptor and caspase–3 were detected using reverse transcription polymerase chain reaction in the cells with or without COX–2 siRNA transfection. …
- NAID 120005472175
- Serum Amyloid A Induces NLRP-3-Mediated IL-1β Secretion in Neutrophils
- Migita Kiyoshi,Izumi Yasumori,Jiuchi Yuka,Kozuru Hideko,Kawahara Chieko,Nakamura Minoru,Nakamura Tadashi,Agematsu Kazunaga,Masumoto Junya,Yasunami Michio,Kawakami Atsushi,Eguchi Katsumi
- PLoS ONE 9(5), e96703, 2014-05-20
- … The cellular supernatants were analyzed by western blot using anti-IL-1β or anti-caspase-1 antibodies. … Furthermore, SAA engaged the caspase-1-activating inflammasome, resulting in the production of active IL-1β. … SAA-induced pro-IL-1β expression was marginally suppressed by the Syk specific inhibitor, R406, and SAA-induced pro-IL-1β processing in neutrophils was prevented by R406. …
- NAID 120005447070
- The GANT61, a GLI Inhibitor, Induces Caspase-Independent Apoptosis of SK-N-LO Cells
- Matsumoto Takahiro,Tabata Keiichi,Suzuki Takashi
- Biological & pharmaceutical bulletin 37(4), 633-641, 2014-04
- NAID 40020030210
Related Links
- Caspase Inhibitor. 製品説明. Z-VAD-FMKは細胞透過性の全カスパーゼ阻害剤で カスパーゼの触媒部位に不可逆的に結合し、アポトーシスの誘導を阻害します（1-4）。 20mMのDMSO溶液として供給されるので、培養細胞や細胞抽出液に加える際に便利 です ...
Related Pictures
★リンクテーブル★
| リンク元 | 「カスパーゼ阻害剤」「カスパーゼ阻害薬」 |
| 関連記事 | 「inhibit」「inhibitor」 |
「カスパーゼ阻害剤」
「カスパーゼ阻害薬」
「inhibit」
- v.
- 抑制する、阻害する、阻止する
- 関
- abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression
「inhibitor」
- n.