WordNet

look over, usually with the intention to rob; "They men cased the housed"
the quantity contained in a case (同)caseful
a specific state of mind that is temporary; "a case of the jitters"
(printing) the receptacle in which a compositor has his type, which is divided into compartments for the different letters, spaces, or numbers; "for English, a compositor will ordinarily have two such cases, the upper case containing the capitals and the lower case containing the small letters" (同)compositor''s case, typesetter''s case
a glass container used to store and display items in a shop or museum or home (同)display case, showcase, vitrine
bed linen consisting of a cover for a pillow; "the burglar carried his loot in a pillowcase" (同)pillowcase, slip, pillow slip
a portable container for carrying several objects; "the musicians left their instrument cases backstage"
nouns or pronouns or adjectives (often marked by inflection) related in some way to other words in a sentence (同)grammatical case
an occurrence of something; "it was a case of bad judgment"; "another instance occurred yesterday"; "but there is always the famous example of the Smiths" (同)instance, example
a person requiring professional services; "a typical case was the suburban housewife described by a marriage counselor"
a problem requiring investigation; "Perry Mason solved the case of the missing heir"
a statement of facts and reasons used to support an argument; "he stated his case clearly"
the actual state of things; "that was not the case"
make known to the authorities; "One student reported the other to the principal"
the act of informing by verbal report; "he heard reports that they were causing trouble"; "by all accounts they were a happy couple" (同)account
a short account of the news; "the report of his speech"; "the story was on the 11 oclock news"; "the account of his speech that was given on the evening news made the governor furious" (同)news report, story, account, write_up
a written document describing the findings of some individual or group; "this accords with the recent study by Hill and Dale" (同)study, written report
a sharp explosive sound (especially the sound of a gun firing); "they heard a violent report followed by silence"
be responsible for reporting the details of, as in journalism; "Snow reported on China in the 1950s"; "The cub reporter covered New York City" (同)cover
to give an account or representation of in words; "Discreet Italian police described it in a manner typically continental" (同)describe, account
announce as the result of an investigation or experience or finding; "Dozens of incidents of wife beatings are reported daily in this city"; "The team reported significant advances in their research"
announce ones presence; "I report to work every day at 9 oclock"
complain about; make a charge against; "I reported her to the supervisor"
the enclosing frame around a door or window opening; "the casings had rotted away and had to be replaced" (同)case
the outermost covering of a pneumatic tire
enclosed in a case
covered or protected with or as if with a case; "knights cased in steel"; "products encased in leatherette" (同)encased, incased
made known or told about; especially presented in a formal account; "his reported opinion"; "the reported findings"

PrepTutorEJDIC

〈C〉(…の)『実例』,事例《+『of』+『名』》 / 《the case》『実情』,真相 / 〈C〉〈U〉『場合』,情況,事情,立場 / 〈C〉(…の)(決定すべき)問題,重大事《+『of』+『名』》 / 〈C〉『訴訟』[『事件』],裁判 / 〈C〉(正当な)論拠,弁護;(被告または原告の)主張,申し立て / 〈C〉病状,容態;(症状から見た)患者 / 〈C〉〈U〉格(名詞・代名詞の語形変化)
(運搬・保管用のいろいろな)『箱』,ケース / (各種の)『容器』,筒,さや,袋,おおい / (標本・陳列用の)ガラス箱,戸だな / (戸・窓などの)わく / 活字箱 / …'を'箱(袋,さやなど)に入れる《+『名』+『up,』+『名』+『up』》
〈C〉(…についての(『報告』,『報道』《+『on』(『of』)+『名』》 / 〈C〉銃声,砲声,爆発音 / 〈U〉〈C〉うわさ,評判 / …‘を'『報告する』,『報道する』 / (上役・警察などの…のことで)〈人〉‘を'『言いつける,訴える』《+『名』〈『人』〉+『to』+『名』+『for』+『名』(doing)》 / (…について)『報告する』《+『on』(『upon』)+『名』(do『ing』)》 / (…に)『出頭する』《+『for』(『to』)+『名』》
箱,包装,おおい / (電線・タイヤなどの)被覆,(ソーセージの)皮 / (ドア・窓などの)わく;額縁

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/11/30 08:58:08」(JST)

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In medicine, a case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. Case reports may contain a demographic profile of the patient, but usually describe an unusual or novel occurrence. Some case reports also contain a literature review of other reported cases.

Types of case reports

Most case reports are on one of six topics:^[1]

An unexpected association between diseases or symptoms.
An unexpected event in the course of observing or treating a patient.
Findings that shed new light on the possible pathogenesis of a disease or an adverse effect.
Unique or rare features of a disease.
Unique therapeutic approaches.
A positional or quantitative variation of the anatomical structures.

Roles in research and education

A case report is generally considered a type of anecdotal evidence.^[2] Given their intrinsic methodological limitations, including lack of statistical sampling, case reports are placed at the foot of the hierarchy of clinical evidence, together with case series.^[3] Nevertheless, case reports do have genuinely useful roles in medical research and evidence-based medicine.^[4] In particular, they have facilitated recognition of new diseases and adverse effects of treatments.^[5] (For example, recognition of the link between administration of thalidomide to mothers and malformations in their babies was triggered by the report of a particular case.)^[6] Case reports have a role in in pharmacovigilance.^[5] They can also help understand the clinical spectrum of rare diseases, as well as unusual presentations of common diseases.^[4] They can help generate study hypotheses, including plausible mechanisms of disease.^[4] Case reports may also have a role to play in guiding the personalization of treatments in clinical practice.^[4]

Proponents of case reports have outlined some particular advantages of the format. Case reports and series have a high sensitivity for detecting novelty and therefore remain one of the cornerstones of medical progress; they provide many new ideas in medicine.^[7] Whereas randomized clinical trials usually only inspect one variable or very few variables, rarely reflecting the full picture of a complicated medical situation, the case report can detail many different aspects of the patient’s medical situation (e.g. patient history, physical examination, diagnosis, psychosocial aspects, follow up).^[8]

Because typical, unremarkable cases are less likely to be published, use of case reports as scientific evidence must take into account publication bias. Some case reports also contain an extensive review of the relevant literature on the topic at-hand (and sometimes a systematic review of available evidence). Reports adopting this sort of approach can be identified by terms such as a "case report and review of the literature". Reports containing broader active research such as this might be considered case studies in the true definition of the term.

Case reports can also play a relevant role in medical education, providing a structure for case-based learning.^[4]

A particular attraction of case reports is the possibility of quick publication (with respect to more extensive studies such as randomized control trials), allowing them to act as a kind of rapid short communication between busy clinicians who may not have the time or resources to conduct large scale research.^[8]

Reporting guidelines

The quality of the scientific reporting of case reports is variable, and sub-optimal reporting hinders the use of case reports to inform research design or help guide clinical practice.^[4] In response to these issues, reporting guidelines are under development to facilitate greater transparency and completeness in the provision of relevant information for individual cases.^[4] The CARE (i.e. CAse REport) guidelines include a reporting checklist that is listed on the EQUATOR Network,^[9] an international initiative aimed at promoting transparent and accurate reporting of health research studies to enhance the value and reliability of medical research literature. Case reports are professional narratives that outline the diagnosis, treatment, and outcomes of the medical problems of patients. Information from case reports provide feedback on clinical practice guidelines and offer a framework for early signals of effectiveness adverse events, and cost. They can be shared for medical, scientific, or educational purposes. This 13-item checklist includes indications regarding the title, key words, abstract, introduction, patient information, clinical findings, timeline, diagnostic assessment, therapeutic interventions, follow-up and outcomes, discussion, patient perspective, and informed consent.^[4]

Publishing case reports

Many international journals will publish case reports, but they restrict the number that appear in the print run because this has an adverse effect on the journal's impact factor. Case reports are often put in the internet part of the journal and there is often still a requirement for a subscription to access them. However there are a few that are devoted to publishing case reports alone, and these are all open access. The first of these to start publishing, in 2001, was Grand Rounds.^[10] Other similar journals include Case Reports in Medicine,^[11] Journal of Medical Case Reports, Oncology Reports, Oncology Letters and Cases Journal; all of them publish peer-reviewed case reports in all areas of medicine. Cases Journal recently merged with the Journal of Medical Case Reports but still maintains an independent internet portal. BMJ Case Reports is an online, peer-reviewed journal publishing cases in all disciplines. Radiology Case Reports^[12] and the Journal of Radiology Case Reports^[13] are open-access peer-reviewed journals focusing on medical imaging. Journal Of Surgical Case Reports^[14] is an open access peer-reviewed journal that considers case reports in the field of surgery. Journal of Orthopaedic Case Reports^[15] is an open access, peer-reviewed journal. Oncology Reports and Oncology Letters both publish case reports exclusively as open access, peer-reviewed journals in the field of oncology and cancer medicine.

There are a number of websites that allow patients to submit and share their own case reports with other people. PatientsLikeMe^[16] and Treatment Report^[17] are two such sites.

Use of term outside science

The term is also used to describe non-scientific reports usually prepared for educational reasons.

Famous scientific case reports

Sigmund Freud reported on numerous cases, including Anna O., Dora, Little Hans, Rat Man, and Wolf Man
Frederick Treves reported on "The Elephant Man"
Paul Broca reported on language impairment following left hemisphere lesions in the 1860s.
Joseph Jules Dejerine reported on a case of pure alexia.
William MacIntyre reported on a case of multiple myeloma (described in the 1840s).
Christiaan Barnard described the world's first heart transplant^[18] as a case report
W. G. McBride, Thalidomide Case Report (1961). The Lancet 2:1358.

References

^ Debra Volkland; Robert L. Iles (1997). Guidebook to better medical writing. Washington, DC: Island Press. ISBN 0-9661831-0-X. OCLC 41579709.
^ Aronson JK (June 2003). "Anecdotes as evidence". BMJ 326 (7403): 1346. doi:10.1136/bmj.326.7403.1346. PMC 1126236. PMID 12816800.
^ Greenhalgh T (July 1997). "How to read a paper. Getting your bearings (deciding what the paper is about)". BMJ 315 (7102): 243–6. doi:10.1136/bmj.315.7102.243. PMC 2127173. PMID 9253275.
^ ^a ^b ^c ^d ^e ^f ^g ^h Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D (2013). "The CARE guidelines: consensus-based clinical case reporting guideline development". Headache 53 (10): 1541–7. doi:10.1111/head.12246. PMID 24266334.
^ ^a ^b Aronson JK, Hauben M (December 2006). "Anecdotes that provide definitive evidence". BMJ 333 (7581): 1267–9. doi:10.1136/bmj.39036.666389.94. PMC 1702478. PMID 17170419.
^ "Thalidomide and congenital abnormalities". James Lind Library. Retrieved 28 May 2014.
^ Vandenbroucke JP (February 2001). "In defense of case reports and case series". Ann. Intern. Med. 134 (4): 330–4. doi:10.7326/0003-4819-134-4-200102200-00017. PMID 11182844.
^ ^a ^b Yitschaky O, Yitschaky M, Zadik Y (May 2011). "Case report on trial: Do you, Doctor, swear to tell the truth, the whole truth and nothing but the truth?" (PDF). J Med Case Reports 5 (1): 179. doi:10.1186/1752-1947-5-179. PMC 3113995. PMID 21569508.
^ "The CARE Guidelines: Consensus-based Clinical Case Reporting Guideline Development". The EQUATOR Network. Retrieved 2014-05-28.
^ "Online open peer-reviewed case report journal". Grand Rounds.
^ "Case Reports in Medicine". hindawi.
^ "Radiology Case Reports".
^ "Case Reports". Journal of Radiology Case Reports.
^ "JSCR". Journal of Surgical Case Reports.
^ "Journal of Orthopaedic Case Reports".
^ "Treatment and Side Effect Information". Patients Like You.
^ "Share and Find Treatment Reviews for Medical Conditions". Treatment Report.
^ "Cardiac transplantation: since the first case report". Grand Rounds.

External links

Case reports – The CARE guidelines

UpToDate Contents

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English Journal

Bilateral femoral neck insufficiency fractures secondary to vitamin D deficiency and concurrent corticosteroid use--a case report.

Carter T1, Nutt J, Simons A.Author information 1Department of Orthogeriatrics, Birmingham Heartlands Hospital, Birmingham, UK, tjcarter@doctors.org.uk.AbstractWe present a rare case of a 67-year-old Indian female who was found to have bilateral insufficiency of the neck of femur fractures secondary to osteomalacia from vitamin D deficiency, with her symptoms exacerbated by a course of oral steroids prescribed for suspected polymyalgia rheumatica.
Archives of osteoporosis.Arch Osteoporos.2014 Dec;9(1):172. doi: 10.1007/s11657-014-0172-5. Epub 2014 Feb 11.
We present a rare case of a 67-year-old Indian female who was found to have bilateral insufficiency of the neck of femur fractures secondary to osteomalacia from vitamin D deficiency, with her symptoms exacerbated by a course of oral steroids prescribed for suspected polymyalgia rheumatica.INTRODUCT
PMID 24515953

Effect of vitamin D in fracture healing in a child: case report.

Parchi P1, Andreani L, Piolanti N, Niccolai F, Cervi V, Lisanti M.Author information 11st Orthopedic Division, Department of Traslational Research and New Technology in Medicine and Surgery, University of Pisa, via Paradisa 2, 56125, Pisa, Italy, parchip@tiscali.it.AbstractIn this report, we describe the effect of vitamin D and calcium supplementation on fracture healing in a young boy with a hypovitaminosis D who had a radius refracture. The radiographic evaluation of the callus formation shows a clear effect of vitamin D on fracture healing in absence of additional variables.
Archives of osteoporosis.Arch Osteoporos.2014 Dec;9(1):170. doi: 10.1007/s11657-013-0170-z. Epub 2014 Jan 23.
In this report, we describe the effect of vitamin D and calcium supplementation on fracture healing in a young boy with a hypovitaminosis D who had a radius refracture. The radiographic evaluation of the callus formation shows a clear effect of vitamin D on fracture healing in absence of additional
PMID 24452512

Adult hepatoblastoma: Case report with adrenal recurrence.

Caso-Maestro O, Justo-Alonso I, Cambra-Molero F, Manrique-Municio A, Calvo-Pulido J, Jiménez-Romero C.
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.Rev Esp Enferm Dig.2014 Dec;105(10):638-639.
PMID 24641466