胆管側多選択性有機アニオントランス・ーター、胆管側多選択性有機アニオン輸送体
- 関
- cMOAT
WordNet
- simple and healthful and close to nature; "an organic lifestyle"
- a fertilizer that is derived from animal or vegetable matter (同)organic fertilizer, organic fertiliser
- being or relating to or derived from or having properties characteristic of living organisms; "organic life"; "organic growth"; "organic remains found in rock"
- involving or affecting physiology or bodily organs; "an organic disease"
- of or relating to foodstuff grown or raised without synthetic fertilizers or pesticides or hormones; "organic eggs"; "organic vegetables"; "organic chicken"
- relating or belonging to the class of chemical compounds having a carbon basis; "hydrocarbons are organic compounds"
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
- a fully differentiated structural and functional unit in an animal that is specialized for some particular function
- a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
- a periodical that is published by a special interest group; "the organ of the communist party"
- a long truck for carrying motor vehicles (同)car transporter
- a crane for moving material with dispatch as in loading and unloading ships
- relating to or like or having a canaliculus
PrepTutorEJDIC
- 有機体の,生物の,生物から生じた / (動植物の)器官の / 有機肥料を用いる(を用いて育った)・有機的な,組織的な,系統的な・有機質の
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
- 自動車運搬用大型トラック
UpToDate Contents
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- 1. ビリルビン代謝bilirubin metabolism [show details]
… the multispecific organic anion transporter, also termed multidrug resistance protein 2 or ATP-binding cassette (ABC) C2 (cMOAT/MRP2/ABCC2), appears to be the most important for the canalicular secretion …
- 2. 高抱合型ビリルビン血症関連の遺伝性疾患inherited disorders associated with conjugated hyperbilirubinemia [show details]
…hepatocyte by the multidrug resistance related protein, MRP2 (also known as the canalicular multispecific organic anion transporter, cMOAT), which is encoded by the ABCC2 gene . The transport is ATP-dependent …
- 3. 黄疸または無症候性高ビリルビン血症の分類および原因classification and causes of jaundice or asymptomatic hyperbilirubinemia [show details]
…not increase until canalicular excretion capacity is exceeded. At that point, a disproportionate amount of conjugated bilirubin accumulates. Most liver diseases affect canalicular excretion, resulting …
- 4. まぶた裂傷eyelid lacerations [show details]
… Thus, trauma to the canalicular system should be suspected when a laceration occurs medially to the punctum on the upper or lower eyelid. Definitive determination of canalicular involvement requires ophthalmologic …
- 5. 黄疸または無症候性高ビリルビン血症成人患者に対する診断的アプローチdiagnostic approach to the adult with jaundice or asymptomatic hyperbilirubinemia [show details]
…unconjugated and conjugated (direct) bilirubin. This may be due to hepatocellular disease, impaired canalicular excretion of bilirubin, or biliary obstruction This is often referred to as conjugated hyperbilirubinemia …
English Journal
- Effect of drug efflux transporters on placental transport of antiretroviral agent abacavir.
- Neumanova Z1, Cerveny L1, Greenwood SL2, Ceckova M1, Staud F3.
- Reproductive toxicology (Elmsford, N.Y.).Reprod Toxicol.2015 Nov;57:176-82. doi: 10.1016/j.reprotox.2015.07.070. Epub 2015 Jul 10.
- Abacavir is as a frequent part of combination antiretroviral therapy used in pregnant women. The aim of this study was to investigate, using in vitro, in situ and ex vivo experimental approaches, whether the transplacental pharmacokinetics of abacavir is affected by ATP-binding cassette (ABC) efflux
- PMID 26169552
- Thiomers: Influence of molecular mass and thiol group content of poly(acrylic acid) on efflux pump inhibition.
- Grabovac V1, Laffleur F1, Bernkop-Schnürch A2.
- International journal of pharmaceutics.Int J Pharm.2015 Sep 30;493(1-2):374-9. doi: 10.1016/j.ijpharm.2015.05.079. Epub 2015 Jul 31.
- The aim of the present study was to investigate the influence of molecular mass and thiol group content of poly(acrylic acid)-cysteine conjugates on the permeation of sulforhodamine 101 and penicillin G. acting as substrates for multidrug resistance-associated protein 2 efflux pump. Poly(acrylic aci
- PMID 26238816
- Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro.
- Jia Y1, Liu Z2, Huo X3, Wang C4, Meng Q5, Liu Q6, Sun H7, Sun P8, Yang X9, Shu X10, Liu K11.
- International journal of pharmaceutics.Int J Pharm.2015 Sep 19. pii: S0378-5173(15)30240-4. doi: 10.1016/j.ijpharm.2015.09.042. [Epub ahead of print]
- The purpose of present study was to assess the enhancing effect of resveratrol (Res) on the absorption of bestatin and clarify the related molecular mechanism. Res facilitated bestatin absorption by down-regulating both protein and gene levels of multidrug resistance 1 (Mdr1) and Multidrug resistanc
- PMID 26394120
Japanese Journal
- A new mutation of the ATP-binding cassette, sub-family C, member 2 (ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome
- Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (cMOAT)
- Trandolaprilat, an Angiotensin-Converting Enzyme Inhibitor, Is Not Excreted in Bile via an ATP-Dependent Active Transporter(cMOAT)
- Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 24(3), 235-240, 2001-05-01
- NAID 10008742789
Related Links
- Mediates hepatobiliary excretion of numerous organic anions and conjugated organic anions such as methotrexate, 17beta-estradiol 17-glucosiduronic acid and leukotriene C4. Also transports sulfated bile salt such as ...
- Protein target information for Canalicular multispecific organic anion transporter 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. ... Canalicular multispecific ...
- This entry represents canalicular multispecific organic anion transporter 1 (also known as MRP2 or ABCC2) from animals. It belongs to the MRP (multidrug resistance protein) subfamily of the ATP-binding cassette (ABC) transporter ...
★リンクテーブル★
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- 関
- canalicular multispecific organic anion transporter
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- 英
- canalicular multispecific organic anion transporter、cMOAT
- 関
- 胆管側多選択性有機アニオントランス・ーター
[★]
- 英
- canalicular multispecific organic anion transporter、cMOAT
- 関
- 胆管側多選択性有機アニオン輸送体
[★]
- 関
- bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation
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- 関
- organic compound、organic matter、organized、organo
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- 関
- canaliculi、canaliculus、ductular、tracheary、tubular
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- 関
- anion transport protein
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トランスポーター
- 関
- translocator、transport protein、transporter protein