WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
PrepTutorEJDIC
- carbonの化学記号
- chromiumの化学記号
- case[s]
UpToDate Contents
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English Journal
- Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis.
- Mortazavi F1,2,3, Lu J4, Phan R5, Lewis M6, Trinidad K7, Aljilani A8, Pezeshkpour G9, Tamanoi F10,11.
- BMC cancer.BMC Cancer.2015 May 9;15(1):381. [Epub ahead of print]
- BACKGROUND: Key effector(s) of mutated KRAS in lung cancer progression and metastasis are unknown. Here we investigated the role of PAK1/Crk axis in transduction of the oncogenic KRAS signal in non-small cell lung cancer (NSCLC).METHODS: We used NSCLC clinical specimens to examine the correlation am
- PMID 25956913
- CRK proteins selectively regulate T cell migration into inflamed tissues.
- Huang Y, Clarke F, Karimi M, Roy NH, Williamson EK, Okumura M, Mochizuki K, Chen EJ, Park TJ, Debes GF, Zhang Y, Curran T, Kambayashi T, Burkhardt JK.
- The Journal of clinical investigation.J Clin Invest.2015 Mar 2;125(3):1019-32. doi: 10.1172/JCI77278. Epub 2015 Jan 26.
- Effector T cell migration into inflamed sites greatly exacerbates tissue destruction and disease severity in inflammatory diseases, including graft-versus-host disease (GVHD). T cell migration into such sites depends heavily on regulated adhesion and migration, but the signaling pathways that coordi
- PMID 25621495
- KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction.
- Gill MB1, Turner R2, Stevenson PG2, Way M3.
- The EMBO journal.EMBO J.2015 Feb 12;34(4):448-65. doi: 10.15252/embj.201490358. Epub 2014 Dec 3.
- Paradoxically, the thymidine kinase (TK) encoded by Kaposi sarcoma-associated herpesvirus (KSHV) is an extremely inefficient nucleoside kinase, when compared to TKs from related herpesviruses. We now show that KSHV-TK, in contrast to HSV1-TK, associates with the actin cytoskeleton and induces extens
- PMID 25471072
Japanese Journal
- 0895 血管平滑筋細胞におけるアンジオテンシンIIのシグナル伝達へのp130^<Cas>とc-Crk IIの関与
- 高橋 知三郎,谷口 隆弘,高橋 明広,小田 明彦,河崎 悟,堂本 康治,横山 光宏,石川 雄一
- Japanese circulation journal 62(SupplementI), 329, 1998-02-28
- NAID 110002562274
- The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol3' kinase pathway
- Cellular proteins binding to the first Src homology 3 (SH3) domain of the proto-oncogene product c-Crk indicate Crk specific signaling pathways
Related Links
- トルコの伝統手工芸“オヤ”からインスパイアされてできた“ビーズの縁飾り”。もともとはムスリム女性が被るスカーフの縁飾りです。レース糸にビーズを通して編み、でき上がった縁飾りを、洋服や雑貨などにつけてリメイクを楽しみます。
- ... of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk. (PubMed id 12878163) 1, 2 Lennartsson J....Ronnstrand L. (2003) DOCK4, a GTPase activator, is disrupted 1, 2 ...
Related Pictures
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- 英
- proto-oncogene protein c-Crk
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癌原遺伝子産物c-Crk
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