WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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1. 下肢末梢動脈疾患の症状を治療するための試験的治療 investigational therapies for treating symptoms of lower extremity peripheral artery disease
2. 初期治療に抵抗性を示したレイノー現象の治療 treatment of the raynaud phenomenon resistant to initial therapy
3. 成人における全身性硬化症（強皮症）の治療および予後の概要 overview of the treatment and prognosis of systemic sclerosis scleroderma in adults
4. 跛行のマネージメント management of claudication
5. 間質性肺疾患関連の肺高血圧症 pulmonary hypertension associated with interstitial lung disease

Human follicular dendritic cells promote germinal center B cell survival by providing prostaglandins.

Kim J, Lee S, Kim YM, Jeoung DI, Choe J.SourceDepartment of Microbiology and Immunology, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do, Republic of Korea.
Molecular immunology.Mol Immunol.2013 Oct;55(3-4):418-23. doi: 10.1016/j.molimm.2013.03.019. Epub 2013 Apr 11.
Evidence for the immunoregulatory function of lipid molecules in addition to proteins is accumulating. Based on our previous reports on the production of prostaglandin E₂ (PGE₂) and prostacyclin by human follicular dendritic cells (FDCs), we hypothesized that these prostaglandins (PGs) have a re
PMID 23583086

Right ventricular electrical remodeling and arrhythmogenic substrate in rat pulmonary hypertension.

Tanaka Y, Takase B, Yao T, Ishihara M.Source1 Division of Biomedical Engineering, National Defense Medical College Research Institute, and.
American journal of respiratory cell and molecular biology.Am J Respir Cell Mol Biol.2013 Sep;49(3):426-36. doi: 10.1165/rcmb.2012-0089OC.
Right ventricular (RV) dysfunction, caused by severe pulmonary hypertension (PH), is associated with high mortality because of RV failure. However, some patients can suffer from sudden cardiac death (SCD). We hypothesized that severe PH can cause RV arrhythmogenesis, leading to SCD. We sought to inv
PMID 23600532

Beraprost sodium improves survival rates in anti-glomerular basement membrane glomerulonephritis and 5/6 nephrectomized chronic kidney disease rats.

Yamaguchi S, Inada C, Tamura M, Sato N, Yamada M, Itaba S, Okazaki S, Matsuura H, Fujii S, Matsuda F, Goto Y, Mochizuki H, Kurumatani H, Miyamoto M.SourcePharmacology Laboratory, Pharmaceutical Research Laboratories, Toray Industries, Inc., Kanagawa 248 8555, Japan. Electronic address: Shinichi_Yamaguchi@nts.toray.co.jp.
European journal of pharmacology.Eur J Pharmacol.2013 Aug 15;714(1-3):325-31. doi: 10.1016/j.ejphar.2013.07.032. Epub 2013 Jul 30.
Beraprost sodium, a stable prostacyclin analog, was showed to improve survival rates in two different rat models, anti-glomerular basement membrane (GBM) glomerulonephritis (GN) and 5/6 nephrectomized (Nx) chronic kidney disease (CKD) rats. In the anti-GBM rat, beraprost sodium (0.2 and 0.6mg/kg/day
PMID 23911885

Effects of beraprost sodium, an oral prostacyclin analog, on insulin resistance in patients with type 2 diabetes

Beraprost Sodium Protects Against Diabetic Nephropathy in Patients with Arteriosclerosis Obliterans: A Prospective, Randomized, Open-label Study

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Journal of Nippon Medical School 82(2), 84-91, 2015
… In this study, we evaluated the effect of combining RAS inhibitor treatment with beraprost sodium (BPS), a prostaglandin I2 analog, in diabetic nephropathy with arteriosclerosis obliterans. …
NAID 130005068457

Beraprost Sodium for Chronic Diabetic Foot Ulcer: A Randomized Controlled Trial in Thammasat University Hospital

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Annals of Vascular Diseases 7(1), 40-45, 2014
… Beraprost sodium, oral form of prostaglandin I2 analogue, maybe used for increasing wound healing.Objective: To compare the healing rate of chronic diabetic foot ulcer between Beraprost sodium and control groups.Design: A single blind randomized trial.Materials and Methods: Fifty non-healed chronic diabetic foot ulcer patients were randomized to be the study and control groups. …
NAID 130004713596