basal forebrain

前脳基底核

• (解剖)前脳基底核

WordNet

1. of primary importance (同)primary
2. serving as or forming a base; "the painter applied a base coat followed by two finishing coats" (同)base
3. the anterior portion of the brain; the part of the brain that develops from the anterior part of the neural tube (同)prosencephalon

PrepTutorEJDIC

1. 基底の,基部の / 基礎的な,基本的な

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/06 02:51:18」(JST)

wiki en

[Wiki en表示]

Basal forebrain
The Basal Forebrain
Details
Latin	pars basalis telencephali
Identifiers
NeuroNames	ancil-1997
NeuroLex ID	Basal Forebrain
TA	A14.1.09.401
FMA	77700
Anatomical terms of neuroanatomy

The basal forebrain is a collection of structures located to the front of and below the striatum. It includes the nucleus accumbens, nucleus basalis, diagonal band of Broca, substantia innominata, and medial septal nuclei. These structures are important in the production of acetylcholine, which is then distributed widely throughout the brain. The basal forebrain is considered to be the major cholinergic output of the central nervous system (CNS).

Function

Acetylcholine is known to promote wakefulness in the basal forebrain. Stimulating the basal forebrain gives rise to acetylcoline release, which induces wakefulness and REM sleep, whereas inhibition of acetylcholine release in the basal forebrain by adenosine causes slow wave sleep.

Adenosine acts on A1 receptors of cholinergic neurons in the basal forebrain. This results in hyperpolarization of cholinergic neurons, which inhibits the release of acetylcholine.

The basal forebrain and adjacent areas are a focus for sleep research. Research, conducted by investigators from Children's Hospital Boston and the University of Helsinki, ties together previous observations about sleep and finds that nitric oxide production in the basal forebrain is both necessary and sufficient to produce sleep.

Clinical significance

Acetylcholine affects the ability of brain cells to transmit information to one another, and also encourages neuronal plasticity, or learning. Thus, damage to the basal forebrain can reduce the amount of acetylcholine in the brain and impair learning. This may be one reason why basal forebrain damage can result in memory impairments such as amnesia and confabulation. One common cause of basal forebrain damage is aneurysm of the anterior communicating artery.

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. パーキンソン病の病因および発症機序 etiology and pathogenesis of parkinson disease
• 2. 母斑性基底細胞癌症候群 nevoid basal cell carcinoma syndrome
• 3. 再発リスクの高い基底細胞癌の治療 treatment of basal cell carcinomas at high risk for recurrence
• 4. 基底細胞癌の疫学および臨床的特徴 epidemiology and clinical features of basal cell carcinoma
• 5. 進行した皮膚扁平上皮癌および基底細胞癌の全身療法 systemic treatment of advanced cutaneous squamous and basal cell carcinomas

English Journal

• Characterization of the bed nucleus of the stria terminalis in the forebrain of anuran amphibians.

• Moreno N, Morona R, López JM, Domínguez L, Joven A, Bandín S, González A.SourceDepartment of Cell Biology, Faculty of Biology, University Complutense of Madrid, Madrid, Spain. nerea@bio.ucm.es
• The Journal of comparative neurology.J Comp Neurol.2012 Feb 1;520(2):330-63. doi: 10.1002/cne.22694.
• Major common features have been reported for the organization of the basal telencephalon in amniotes, and most characteristics were thought to be acquired in the transition from anamniotes to amniotes. However, gene expression, neurochemical, and hodological data obtained for the basal ganglia and s
• PMID 21674496

• Integrating perspectives on vocal performance and consistency.

• Sakata JT, Vehrencamp SL.SourceDepartment of Biology, McGill University, Montreal, QC, Canada, H3A 1B1.
• The Journal of experimental biology.J Exp Biol.2012 Jan 15;215(Pt 2):201-9.
• Recent experiments in divergent fields of birdsong have revealed that vocal performance is important for reproductive success and under active control by distinct neural circuits. Vocal consistency, the degree to which the spectral properties (e.g. dominant or fundamental frequency) of song elements
• PMID 22189763

Japanese Journal

• Diabetes-Induced Central Cholinergic Neuronal Loss and Cognitive Deficit Are Attenuated by Tacrine and a Chinese Herbal Prescription, Kangen-Karyu : Elucidation in Type 2 Diabetes db/db Mice

• Zhao Qi,Matsumoto Kinzo,Tsuneyama Koichi [他],TANAKA Ken,LI Feng,SHIBAHARA Naotoshi,MIYATA Takeshi,YOKOZAWA Takako
• Journal of pharmacological sciences 117(4), 230-242, 2011-12-20
• … Expression levels of central cholinergic marker proteins in the hippocampus and the number of cholinergic cells in the medial septum and basal forebrain were also significantly lower in O-<I>db/db</I> …
• NAID 10030453612

• Control of cerebral cortical blood flow by stimulation of basal forebrain cholinergic areas in mice

• Hotta Harumi,Uchida Sae,Kagitani Fusako [他],MARUYAMA Naoki
• The journal of physiological sciences : JPS 61(3), 201-209, 2011-05-01
• NAID 10029050056

• インディアナ便り(9)鼻から脳へのGnRHニューロンの移動

• 小山 幸子
• Aroma research 12(3), 288-291, 2011-00-00
• NAID 40018970775

Related Pictures

---

★リンクテーブル★

拡張検索	「magnocellular basal forebrain nuclei」
関連記事	「basal」

「magnocellular basal forebrain nuclei」

　　[★] 大細胞性基底前脳核群

「basal」

　　[★]

• adj.

• 基礎の、基本の、基底の

関

base、basement、bases、basic、basis、element、elementary、fundamental、fundamentals、fundus、ground