アクアコバラミン
English Journal
- Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.
- Gherasim C1, Ruetz M1, Li Z1, Hudolin S1, Banerjee R2.
- The Journal of biological chemistry.J Biol Chem.2015 May 1;290(18):11393-402. doi: 10.1074/jbc.M115.637132. Epub 2015 Mar 25.
- Human CblC catalyzes the elimination of the upper axial ligand in cobalamin or B12 derivatives entering the cell from circulation. This processing step is critical for assimilation of dietary cobalamin into the active cofactor forms that support the B12-dependent enzymes, methionine synthase and met
- PMID 25809485
- Synthesis and Properties of Formylcobalamin and Propionylcobalamin, Novel Acylcobalamins.
- Toraya T, Ohya Y.
- Journal of nutritional science and vitaminology.J Nutr Sci Vitaminol (Tokyo).2015;61(1):8-13.
- Formylcobalamin (formyl-Cbl), a C1-unit carrying corrinoid, and propionylcobalamin (propionyl-Cbl) were synthesized for the first time, and their properties were compared with those of acetylcobalamin (acetyl-Cbl). Formyl-Cbl, acetyl-Cbl, and propionyl-Cbl were decomposed by a NH2OH treatment, formi
- PMID 25994134
- The extracellular heme-binding protein HbpS from the soil bacterium Streptomyces reticuli is an aquo-cobalamin binder.
- Ortiz de Orué Lucana D1, Fedosov SN2, Wedderhoff I3, Che EN3, Torda AE4.
- The Journal of biological chemistry.J Biol Chem.2014 Dec 5;289(49):34214-28. doi: 10.1074/jbc.M114.585489. Epub 2014 Oct 23.
- The extracellular protein HbpS from Streptomyces reticuli interacts with iron ions and heme. It also acts in concert with the two-component sensing system SenS-SenR in response to oxidative stress. Sequence comparisons suggested that the protein may bind a cobalamin. UV-visible spectroscopy confirme
- PMID 25342754
Japanese Journal
- Synthesis, Properties and Microbiological Activity of Hydrophobic Derivatives of Vitamin B12.
- , , , ,
- Journal of Nutritional Science and Vitaminology 41(5), 515-526, 1995
- … Long chain alkylcobalamins were easily converted to aquacobalamin by photoirradia-tion, but the first-order rate constant of photolysis decreased with the length of an alkyl group. …
- NAID 130001370053
- 4.補酵素型Cobalamin変換欠損Fibloblast細胞のAquacobalamin Reductase活性について : ビタミンB研究委員会 第335回会議研究発表要旨
- 単細胞真核生物におけるビタミンB_<12>の結合タンパク質ならびに還元酵素に関する研究
- 渡辺 文雄
- ビタミン 66(11), 617-625, 1992-11-25
- … Aquacobalamin reductases catalyzing the reduction of aquacobalamin to cob(II)alamin in the synthesis of Cbl coenzymes were purified and characterized from Euglena mitochondria and rat liver. …
- NAID 110002849191
Related Links
- Introduction guidelines Aquacobalamin is one of the major forms of vitamin B(12) isolated from mammalian cells. Aquacobalamin and the thiolate forms of glutathione are the precursors of glutathionylcobalamin (GSCbl, a precursor to ...
- Look at other dictionaries: Aquacobalamin reductase (NADPH) — In enzymology, an aquacobalamin reductase (NADPH) (EC number|1.16.1.5) is an enzyme that catalyzes the chemical reaction:2 cob(II)alamin + NADP+ ...
Related Pictures
★リンクテーブル★
[★]
- 英
- hydroxocobalamin
- ラ
- hydroxocobalaminum
- 同
- アクアコバラミン aquacobalamin、ビタミンB12a vitamin B12a、OHB12
- 化
- 塩酸ヒドロキソコバラミン hydroxocobalamin hydrochloride、酢酸ヒドロキソコバラミン hydroxocobalamin acetate
- 商
- フレスミン、シアノキット、マスブロン、ドセラン、Codroxomin, Hybalamin
- ビタルファ、ビースリミン、ノルニチカミン、ネオラミン・スリービー、ナイロジン、トライビー、ジアイナミックス、コンベルビー(チアミンジスルフィド、ピリドキシン、ヒドロキソコバラミン)
- ビタノイリン(フルスルチアミン、ピリドキサール、ヒドロキソコバラミン)
- トリドセラン(チアミン、ピリドキシン、ヒドロキソコバラミン)
- ビタダン、ビタマル(フルスルチアミン、ピリドキサール、リボフラビン、ヒドロキソコバラミン)
- 関
- ビタミンB12