同: EDA-ID

WordNet

having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
a message whose ingenuity or verbal skill or incongruity has the power to evoke laughter (同)humor, humour, witticism, wittiness
immunological disorder in which some part of the bodys immune system is inadequate and resistance to infectious diseases is reduced
of or relating to the ectoderm (同)ectodermic

PrepTutorEJDIC

〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
《随伴・協調》…『と』,と共に,といっしょに / 《所有・所持》…『を持っている』,がある,の付いた / 《道具・手段》…『で』,を使って / 《財料・供給物》…『で』,を与えて / …を支持して,に賛成して / …『に反対(敵対)して』,を相手として / …『と同時に』,と同様に / …『に比べて』,に比例して / 《様態》《名詞を伴い副詞句として》『…で』,を示して,をもって / 《付帯状競》…『して』,しながら / 《譲歩》…がありながら,にもかかわらず / 『…が原因で』,のために,…で / …に任せて,のもとにあずけて,のところに / …に関して,について / …から離れて / 《連結・混合》…と / 《副詞と共に命令文で》
知る(know)
〈U〉『機知』,機転,ウィット / 〈C〉『機知に富む人』,機転のきく人 / 《複数形で;単数扱い》『理解(表現)力』,知性 / 《複数形で》(物事を見抜いたりもくろんだりする)才覚,才知 / 《複数形で;単数扱い》正気

UpToDate Contents

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1. 遺伝性皮膚症 the genodermatoses
2. 複合免疫不全 combined immunodeficiencies
3. 原発性免疫不全症のための造血細胞移植 hematopoietic cell transplantation for primary immunodeficiency
4. Hyperimmunoglobulin M syndromes
5. NK細胞欠損症候群：臨床症状および診断 nk cell deficiency syndromes clinical manifestations and diagnosis

English Journal

B cells from nuclear factor kB essential modulator deficient patients fail to differentiate to antibody secreting cells in response to TLR9 ligand.

Giardino G1, Cirillo E1, Gallo V1, Esposito T1, Fusco F2, Conte MI2, Quinti I3, Ursini MV2, Carsetti R4, Pignata C5.
Clinical immunology (Orlando, Fla.).Clin Immunol.2015 Aug 22;161(2):131-135. doi: 10.1016/j.clim.2015.08.008. [Epub ahead of print]
Hypohidrotic ectodermal dysplasia (HED) consists of disorders resulting from molecular alterations of ectodysplasin-A (EDA) pathway. Hypomorphic mutations in NF-kB essential modulator, downstream EDA, result in HED with immunodeficiency (HED-ID), characterized by susceptibility to encapsulated pyoge
PMID 26307434

Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies.

D'Assante R1, Fusco A, Palamaro L, Giardino G, Gallo V, Cirillo E, Pignata C.
International reviews of immunology.Int Rev Immunol.2015 Mar 16. [Epub ahead of print]
Primary immunodeficiencies (PIDs) include a heterogeneous group of mostly monogenic diseases characterized by functional/developmental alterations of the immune system. Skin and skin annexa abnormalities may be a warning sign of immunodeficiency, since both epidermal and thymic epithelium have ectod
PMID 25774666

Novel TTC37 Mutations in a Patient with Immunodeficiency without Diarrhea: Extending the Phenotype of Trichohepatoenteric Syndrome.

Rider NL1, Boisson B2, Jyonouchi S3, Hanson EP4, Rosenzweig SD5, Cassanova JL6, Orange JS1.
Frontiers in pediatrics.Front Pediatr.2015 Jan 30;3:2. doi: 10.3389/fped.2015.00002. eCollection 2015.
Unbiased genetic diagnosis has increasingly associated seemingly unrelated somatic and immunological phenotypes. We report a male infant who presented within the first year of life with physical growth impairment, feeding difficulties, hyperemesis without diarrhea, and abnormal hair findings suggest
PMID 25688341

Japanese Journal

Hypercalcemia Following Umbilical Cord Blood Transplantation to Correct Osteopetrosis Associated with the NEMO Mutation [Innovation in Transplant and Regenerative Medicine. The 13th Meeting of Hirosaki International Forum of Medical Science. Communication Center of Hirosaki University School of Medicine. September 9, 2011, Hirosaki, Japan]

Sasaki Shinya,Kamio Takuya,Kudo Ko [他],Sato Tomohiko,Tono Chikako,Takahashi Yoshihiro,Terui Kiminori,Ito Etsuro
弘前醫學 64(Supplement), S86-S89, 2013
… X-linked recessive anhidrotic ectodermal dysplasia with immunodeficiency（ XL-EDA-ID） is a congenital developmental and immunologic disorder, which often causes osteopetrosis. … These individuals are susceptible to infection with various microorganisms, and most patients die of infection before reaching maturity. …
NAID 110009623619

Diagnosis and Treatment in Anhidrotic Ectodermal Dysplasia with Immunodeficiency

Kawai Tomoki,Nishikomori Ryuta,Heike Toshio
Allergology International 61(2), 207-217, 2012
… Anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) is characterized according to its various manifestations, which include ectodermal dysplasia, vascular anomalies, osteopetrosis, and diverse immunological abnormalities such as susceptibility to pathogens, impaired antibody responses to polysaccharides, hypogammaglobulinemia, hyper-IgM syndrome, impaired natural killer cell …
NAID 130004477140

A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and Tumor Necrosis Factor-mediated NF-kappaB activation