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1. 小児や青年への性的虐待の評価evaluation of sexual abuse in children and adolescents [show details]
… Behcet syndrome Perineal hemangiomas (of the labia, hymen, perihymenal area, or urethra) Mongolian spots can look like bruises Anal conditions that may be associated with perianal bleeding or bruising …
2. 肛門そう痒症患者へのアプローチapproach to the patient with anal pruritus [show details]
…flattening internal hemorrhoids. In patients with anal pruritus, initial management consists of improving anal hygiene, avoiding moisture in the anal area, removing offending agents, dietary modification …
3. 裂肛：内科的マネージメントanal fissure medical management [show details]
…hair dryer on low heat setting) the anal area well. Although topical analgesic jelly or creams (eg, 2% lidocaine jelly) are often prescribed for patients with an anal fissure for pain control, their use …
4. クローン病の肛門病変perianal crohns disease [show details]
… similar to that for patients with anal or colorectal malignancies. Perianal abscess should be suspected in patients who present with constant pain in the anal or rectal area, fever or purulent discharge …
5. 痔疾患の外科的治療surgical treatment of hemorrhoidal disease [show details]
…hemorrhoidal tissue (in the absence of a clot). Following excision of an external hemorrhoid, the anal area is covered by a dressing to protect the clothing from soilage. For nonsurgeons who do not feel …

English Journal

Bifunctional S, N-Codoped carbon dots-based novel electrochemiluminescent bioassay for ultrasensitive detection of atrazine using activated mesoporous biocarbon as enzyme nanocarriers.

Wu Y, Chen Y, Zhang S, Zhang L, Gong J.
Analytica chimica acta. 2019 Sep;1073()45-53.
A novel and ultrasensitive electrochemiluminescent (ECL) bioassay has been developed for the detection of atrazine (ATZ), whereby bifunctional S, N-codoped carbon dots (S, N-CDs) and activated mesoporous bicarbons (BCs) have been innovatively integrated to synergistically amplify the ECL signal. Whe
PMID 31146835

A novel on-flow mass spectrometry-based dual enzyme assay.

Seidl C, Vilela AFL, Lima JM, Leme GM, Cardoso CL.
Analytica chimica acta. 2019 Sep;1072()81-86.
This work describes a new simultaneous on-flow dual parallel enzyme assay based on immobilized enzyme reactors (ICERs) with mass spectrometry detection. The novelty of this work relies on the fact that two different enzymes can be screened at the same time with only one single sample injection and i
PMID 31146868

Nanotoxicity assessment: A challenging application for cutting edge electroanalytical tools.

Bettazzi F, Palchetti I.
Analytica chimica acta. 2019 Sep;1072()61-74.
In the recent years, the number of commercial products containing engineered nanomaterials (ENMs) has increased exponentially. Consequently, the toxicological profile of ENMs on the ecosystems as well as on human health has to be carefully evaluated. Nanotoxicology, an interdisciplinary research are
PMID 31146866

Japanese Journal

肛門近傍の創へNPWTを用いる際の一工夫:～殿溝皮弁の有用性～

桒水流健二,櫻井敦,谷口智哉,三谷寛子
創傷 10(1), 1-7, 2019
殿部の創傷に対し，創面環境調整（wound bed preparation，以下WBP）や植皮片固定を目的に，局所陰圧閉鎖療法（Negative Pressure Wound Therapy，以下NPWT）を用いる場合がある。しかし病変が肛門近傍に及ぶ場合，複雑な形状や浸軟でフィルムの固定が不安定となりリークや便汚染が危惧される。今回われわれは，殿部慢性化膿性汗腺炎の治療において殿溝皮 …
NAID 130007542992

Anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease, successfully treated with modified FOLFOX6: a case report

山田武史,森脇俊和,渡邉玲,兵頭一之介
BMC cancer 18(1), 1142, 2018-11
… Anal canal cancer occasionally accompanies extramammary Paget disease. … Although most of themare squamous cell carcinoma, anal canal adenocarcinoma with neuroendocrine features accompanying secondaryextramammary Paget disease has never been reported.Case presentation:Here, we report a 76-year-old man presented with pruritus in the perianal area. … The anal canal tumor was confirmed by digital examinationand endoscopy. …
NAID 120006583028

潰瘍性大腸炎に対し大腸全摘・J型回腸囊肛門吻合術後にileal castを生じた1例

皆川知洋,廣田誠一,内野基,池内浩基,桑原隆一,堀尾勇規,佐々木寛文,蝶野晃弘,坂東俊宏,木原多佳子,井出良浩
日本消化器外科学会雑誌 51(10), 649-655, 2018
… <p>症例は47歳の男性で，潰瘍性大腸炎（ulcerative colitis；以下，UCと略記）に対し，大腸全摘・J型回腸囊肛門吻合術（ileal pouch anal anastomosis；以下，IPAAと略記），回腸人工肛門造設術を施行した．入院中に肛門より膿性粘液の排出を認めたが，抗生剤タゾバクタム／ピペラシリン（tazobactam/piperacillin）投与にて改善した．退院後に肛門からstapleを伴った粘膜の脱出があり来院された．内視鏡検査ではJ型回腸囊（ileal …
NAID 130007502440