WordNet

place signs, as along a road; "sign an intersection"; "This road has been signed"
(medicine) any objective evidence of the presence of a disorder or disease; "there were no signs of asphyxiation"
a perceptible indication of something not immediately apparent (as a visible clue that something has happened); "he showed signs of strain"; "they welcomed the signs of spring" (同)mark
a character indicating a relation between quantities; "dont forget the minus sign"
a fundamental linguistic unit linking a signifier to that which is signified; "The bond between the signifier and the signified is arbitrary"--de Saussure
a gesture that is part of a sign language
a public display of a message; "he posted signs in all the shop windows"
engage by written agreement; "They signed two new pitchers for the next season" (同)contract, sign on, sign_up
approve and express assent, responsibility, or obligation; "All parties ratified the peace treaty"; "Have you signed your contract yet?" (同)ratify
communicate silently and non-verbally by signals or signs; "He signed his disapproval with a dismissive hand gesture"; "The diner signaled the waiters to bring the menu" (同)signal, signalize, signalise
mark with ones signature; write ones name (on); "She signed the letter and sent it off"; "Please sign here" (同)subscribe
be engaged by a written agreement; "He signed to play the casino on Dec. 18"; "The soprano signed to sing the new opera"
communicate in sign language; "I dont know how to sign, so I could not communicate with my deaf cousin"
having a handwritten signature; "a signed letter"

PrepTutorEJDIC

(ある事実・状態・感情などの)『表れ』,印,気配,徴侯(indication);(…の)こん跡,計跡《+『of』+『名』》・『身ぶり』,手まね,合図 / 『標識』,看板 / (数学・音楽などの)記号 / (…の)『象徴』,シンボル(symbol)《+『of』+『名』》・《文》(…の)『前兆』,きざし《+『of』+『名』》・宮(きゅう)(黄道12区分の一つ) ・〈手紙・書類・作品など〉‘に'『署名する』・(…に)〈名前など〉‘を'書く《+『名』+『on』(『to』)+『名』》 / …‘を'雇う契約に署名する・…‘を'合図する,知らせる;…に合図する・署名する・契約書に署名して雇われる
=ti

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/07/18 11:54:26」(JST)

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Kehr's sign is the occurrence of acute pain in the tip of the shoulder due to the presence of blood or other irritants in the peritoneal cavity when a person is lying down and the legs are elevated. Kehr's sign in the left shoulder is considered a classical symptom of a ruptured spleen.^[1] May result from diaphragmatic or peridiaphragmatic lesions, renal calculi, splenic injury or ruptured ectopic pregnancy.

Kehr's sign is a classical example of referred pain: irritation of the diaphragm is signalled by the phrenic nerve as pain in the area above the collarbone. This is because the supraclavicular nerves have the same cervical nerves origin as the phrenic nerve, C3 and C4.

The discovery of this is often attributed to a German gall bladder surgeon named Hans Kehr, but extensive studies into research he conducted during his life shows inconclusive evidence as to whether or not he actually discovered it.^[2]

References

^ Rutkow IM (June 1978). "Rupture of the spleen in infectious mononucleosis: a critical review". Arch Surg 113 (6): 718–20. PMID 655846.
^ Klimpel V (2004). "Does Kehr's sign derive from Hans Kehr? A critical commentary on its documentation?". Chirurg 75 (1): 80–3. doi:10.1007/s00104-003-0796-2. PMID 14740133.

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UpToDate Contents

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1. 救急外来における成人の腹痛の評価 evaluation of the adult with abdominal pain in the emergency department
2. 肩関節の訴えがある患者の評価 evaluation of the patient with shoulder complaints
3. 小児における腹部の鈍的外傷の概要 overview of blunt abdominal trauma in children
4. 鈍的腹部外傷のある子供の肝臓、脾臓、および膵臓の損傷 liver spleen and pancreas injury in children with blunt abdominal trauma
5. Overview of eye injuries in the emergency department

English Journal

Traditional Kehr's sign: Left shoulder pain related to splenic abscess.

Söyüncü S, Bektaş F, Cete Y.SourceDepartment of Emergency Medicine, Akdeniz University, Antalya, Turkey.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES.Ulus Travma Acil Cerrahi Derg.2012 Jan;18(1):87-8. doi: 10.5505/tjtes.2011.04874.
Kehrs sign was originally described by the German surgeon Hans Kehr (1862-1916). It is a classical example of referred pain: irritation of the diaphragm is signaled by the phrenic nerve as pain in the area above the clavicle. We present a case of a 21-year-old woman admitted to the emergency depar
PMID 22290058

Microvirin, a novel alpha(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of cyanovirin-N but a much higher safety profile.

Huskens D, Férir G, Vermeire K, Kehr JC, Balzarini J, Dittmann E, Schols D.SourceRega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
The Journal of biological chemistry.J Biol Chem.2010 Aug 6;285(32):24845-54. Epub 2010 May 27.
Microvirin (MVN), a recently isolated lectin from the cyanobacterium Microcystis aeruginosa PCC7806, shares 33% identity with the potent anti-human immunodeficiency virus (HIV) protein cyanovirin-N (CV-N) isolated from Nostoc ellipsosporum, and both lectins bind to similar carbohydrate structures. M
PMID 20507987