WordNet

limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
limit the range or extent of; "Contact between the young was inhibited by strict social customs"
a substance that retards or stops an activity
of or involving the pancreas; "pancreatic cancer"
an enzyme of pancreatic origin; catalyzes the hydrolysis of proteins to smaller polypeptide units

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1. 小児および思春期における慢性膵炎の原因 causes of chronic pancreatitis in children and adolescents
2. 遺伝性膵炎 hereditary pancreatitis
3. 小児における慢性膵炎の臨床症状および診断 clinical manifestations and diagnosis of chronic pancreatitis in children
4. 急性膵炎の臨床症状および診断 clinical manifestations and diagnosis of acute pancreatitis
5. 成人における慢性膵炎の臨床症状および診断 clinical manifestations and diagnosis of chronic pancreatitis in adults

Heterologous expression of Cenchritis muricatus protease inhibitor II (CmPI-II) in Pichia pastoris system: Purification, isotopic labeling and preliminary characterization.

Cabrera-Muñoz A1, Rojas L2, Gil DF3, González-González Y4, Mansur M5, Camejo A6, Pires JR7, Alonso-Del-Rivero Antigua M8.
Protein expression and purification.Protein Expr Purif.2016 Jun 25;126:127-136. doi: 10.1016/j.pep.2016.06.011. [Epub ahead of print]
Cenchritis muricatus protease inhibitor II (CmPI-II) is a tight-binding serine protease inhibitor of the Kazal family with an atypical broad specificity, being active against several proteases such as bovine pancreatic trypsin, human neutrophil elastase and subtilisin A. CmPI-II 3D structures are ne
PMID 27353494

(1)H, (13)C and (15)N resonance assignments and secondary structure analysis of CmPI-II, a serine protease inhibitor isolated from marine snail Cenchritis muricatus.

Cabrera-Muñoz A1, Rojas L1, Alonso-Del-Rivero Antigua M1, Pires JR2.
Biomolecular NMR assignments.Biomol NMR Assign.2016 Apr;10(1):153-6. doi: 10.1007/s12104-015-9656-5. Epub 2015 Nov 7.
A protease inhibitor (CmPI-II) (UNIPROT: IPK2_CENMR) from the marine mollusc Cenchritis muricatus, has been isolated and characterized. It is the first member of a new group (group 3) of non-classical Kazal-type inhibitors. CmPI-II is a tight-binding inhibitor of serine proteases: trypsin, human neu
PMID 26547437

Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.

Wang G1, Liu X1, Gaertig MA2, Li S3, Li XJ4.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2016 Mar 22;113(12):3359-64. doi: 10.1073/pnas.1524575113. Epub 2016 Mar 7.
The Huntington's disease (HD) protein, huntingtin (HTT), is essential for early development. Because suppressing the expression of mutantHTTis an important approach to treat the disease, we must first understand the normal function of Htt in adults versus younger animals. Using inducibleHttknockout
PMID 26951659

Serine protease inhibitor Kazal type 1 and epidermal growth factor receptor are expressed in pancreatic tubular adenocarcinoma, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia