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1. 非閉塞性腸間膜虚血nonocclusive mesenteric ischemia [show details]
…protein (I-FABP) level. In one review, nonocclusive mesenteric ischemia developed in 29 percent of septic shock patients with elevated I-FABP patients compared with 2 percent of those with normal I-FABP . The…
2. 非ST上昇型心筋梗塞後の有害転帰の危険因子risk factors for adverse outcomes after non st elevation acute coronary syndromes [show details]
…myocardial infarction . The ability of H-FABP to predict cardiovascular outcomes was evaluated in 2287 patients with ACS enrolled in the OPUS-TIMI 16 trial . H-FABP was elevated (>8 ng per mL) in 332 patients …
3. 急性尿細管壊死の研究用バイオマーカーおよび評価investigational biomarkers and the evaluation of acute tubular necrosis [show details]
…urinary IL-18 as a biomarker. Urinary excretion of urinary liver-type fatty acid-binding protein (L-FABP) reflects stress of proximal tubular epithelial cells and correlates with severity of ischemic tubular …
4. 成人における腸虚血の概要overview of intestinal ischemia in adults [show details]
…mesenteric infarction, have been found to have significant elevations in I-FABP . In a prospective study that evaluated 287 patients, I-FABP levels were significantly elevated for vascular (31 versus 2.5 ng/mL) …
5. 先天性肺気道奇形の出生前診断およびマネージメントprenatal diagnosis and management of congenital pulmonary airway malformation [show details]
…of CPAM is not known, and associations with different genes have been suggested, including TTF-1 , FABP-7 , FGF-7, FGF-9, FGF-10, Hoxb-5, and SOX2 . Parents need to be counseled about the possible course…

English Journal

I-FABP, Pig-MAP and TNF-α as biomarkers for monitoring gut-wall integrity in front of Salmonella Typhimurium and ETEC K88 infection in a weaned piglet model.

López-Colom P, Yu K, Barba-Vidal E, Saco Y, Martín-Orúe SM, Castillejos L, Solà-Oriol D, Bassols A.
Research in veterinary science. 2019 May;124()426-432.
Having sensitive serum biomarkers able to determine the structural changes of the small intestine suffering from bacterial digestive diseases could be a valuable tool particularly in piglets at weaning, when intestinal infections are highly prevalent. We evaluated the usefulness of three inflammator
PMID 31082572

Serum Markers Associated with Severity and Outcome of Hantavirus Pulmonary Syndrome.

Maleki KT, García M, Iglesias A, Alonso D, Ciancaglini M, Hammar U, Ljunggren HG, Schierloh P, Martínez VP, Klingström J.
The Journal of infectious diseases. 2019 May;219(11)1832-1840.
Hantavirus pulmonary syndrome (HPS) is caused by Andes virus (ANDV) and related hantaviruses in the Americas. Despite a fatality rate of 40%, the pathogenesis of HPS is poorly understood and factors associated with severity, fatality, and survival remain elusive. Ninety-three ANDV-infected HPS patie
PMID 30698699

Effects of hydroxyethyl starch (HES 130/0.42) on endothelial and epithelial permeability in vitro.

Wong YL, Lautenschläger I, Zitta K, Hummitzsch L, Parczany K, Steinfath M, Weiler N, Albrecht M.
Toxicology in vitro : an international journal published in association with BIBRA. 2019 May;60()36-43.
Hydroxyethyl starch (HES) is employed to sustain normovolemia in patients. Using a perfused organ model, we recently showed that HES impairs the intestinal barrier which is constituted of endothelial and epithelial cell layers. However, the target cells and molecular actions of HES in the intestine
PMID 31059770

Japanese Journal

Evidence for the involvement of FXR signaling in ovarian granulosa cell function

TAKAE Kentaro,NAKATA Mizuho,WATANABE Takafumi,SASADA Hiroshi,FUJII Hiroshi,TOMIOKA Ikuo
家畜繁殖学雑誌 65(1), 47-55, 2019
… Farnesoid X receptor (FXR) is mainly present in enterohepatic tissues and regulates cholesterol, lipid, and glucose homeostasis in coordination with target genes such as SHP … and FABP6. … In situ …
NAID 130007593830

Evidence for the involvement of FXR signaling in ovarian granulosa cell function

TAKAE Kentaro,NAKATA Mizuho,WATANABE Takafumi,SASADA Hiroshi,FUJII Hiroshi,TOMIOKA Ikuo
家畜繁殖学雑誌, 2018
… FXR (farnesoid X receptor) is mainly present in enterohepatic tissues and regulates cholesterol, lipid, and glucose homeostasis in coordination with target genes such as SHP … and FABP6. … In situ …
NAID 130007514194

心的外傷後ストレス症候群（PTSD）の神経機序と治療戦略

福永浩司,矢吹悌,高畑伊吹,松尾和哉
日本薬理学雑誌 152(4), 194-201, 2018
… （FABP7）の遺伝子欠損マウスではPTSD様の不安行動と恐怖記憶の固定が亢進される．私達はFABP3欠損マウスにおいて恐怖記憶消去系が障害されること，多動と認知機能障害がみられPTSD様症状を呈すること見出した．さらに，睡眠障害治療薬でメラトニン受容体作用薬であるラメルテオンの経口投与がFABP3欠損マウスのPTSD様行動を改善することを見出した．FABP3欠 …
NAID 130007495997