WordNet
- first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
- the 1st letter of the Greek alphabet
- the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
- early testing stage of a software or hardware product; "alpha version"
- a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
- the 7th letter of the Roman alphabet (同)g
- any high mountain
PrepTutorEJDIC
- アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
- 高山,高峰
UpToDate Contents
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English Journal
- The hinge region of the scaffolding protein of cell contacts, zonula occludens protein 1, regulates interacting with various signaling proteins.
- Bal MS1, Castro V, Piontek J, Rueckert C, Walter JK, Shymanets A, Kurig B, Haase H, Nürnberg B, Blasig IE.
- Journal of cellular biochemistry.J Cell Biochem.2012 Mar;113(3):934-45.
- Zonula occludens protein 1 (ZO-1) is a ubiquitous scaffolding protein, but it is unknown why it functions in very different cellular contacts. We hypothesized that a specific segment, the unique hinge region, can be bound by very different regulatory proteins. Using surface plasmon resonance spectro
- PMID 22371973
- G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions.
- Kremer KN1, Kumar A, Hedin KE.
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2011 Sep 15;187(6):3177-85. doi: 10.4049/jimmunol.1100206. Epub 2011 Aug 19.
- RasGRP1, a Ras guanine-nucleotide exchange factor, critically mediates T cell development and function and controls immunodeficiency and autoimmunity. In this study, we describe a unique mechanism of mobilization and activation of RasGRP1 in response to SDF-1, a chemokine that signals via the G prot
- PMID 21856938
- RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.
- Talbot JN1, Jutkiewicz EM, Graves SM, Clemans CF, Nicol MR, Mortensen RM, Huang X, Neubig RR, Traynor JR.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2010 Jun 15;107(24):11086-91. doi: 10.1073/pnas.1000003107. Epub 2010 Jun 2.
- Elevating serotonin (5-HT) levels with selective serotonin reuptake inhibitors (SSRIs) is the most widely used treatment for depression. However, current therapies are ineffective, have delayed benefit, or cause side effects in many patients. Here, we define a mechanism downstream of 5-HT1A receptor
- PMID 20534514
Japanese Journal
- Vomeronasal phenotype and behavioral alterations in G alpha i2 mutant mice
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- G-alpha i2 Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit ...
Related Pictures
★リンクテーブル★
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- 英
- G-alpha-i2
- 関
- Gαi2サブユニット
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- 英
- G-alpha-i2
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- Gαi2
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α、アルファ
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- alfa
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ヨウ素
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- I、iodide、iodine
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- 同
- ガドリニウム造影MRI
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グラム
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- gram