Fanconi anemia complementation group protein

ファンコニ貧血相補群タンパク質

WordNet

1. arrange into a group or groups; "Can you group these shapes together?"
2. (chemistry) two or more atoms bound together as a single unit and forming part of a molecule (同)radical, chemical group
3. any number of entities (members) considered as a unit (同)grouping
4. a set that is closed, associative, has an identity element and every element has an inverse (同)mathematical group
5. form a group or group together (同)aggroup
6. the activity of putting things together in groups
7. a system for classifying things into groups (同)pigeonholing
8. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
9. a deficiency of red blood cells (同)anaemia
10. a lack of vitality (同)anaemia
11. the grammatical relation of a word or phrase to a predicate

PrepTutorEJDIC

1. (…の)『群れ』,集まり,小集団《+of+名》 / (主義・系統・種類などを同じくする人・物の)『派』,『団体』 / (ポミュラーソング歌手の)グループ / (動・植物分類上の)群;(化学の)基,原子団;(地質学上の)界;(数学の)群;(言語学上の)語派 / …‘を'一群に集める,一団にする《+『名』+『together』》 / (系統的に)…‘を'分類する,調和よく配合する《+『名』+『together』》 / 集まる,群(集団)をなす
2. グループに分けること;分類法 / (集まった物の)配置,配合
3. 蛋白(たんばく)質

UpToDate Contents

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• 1. 再生不良性貧血：病因、臨床症状および診断 aplastic anemia pathogenesis clinical manifestations and diagnosis
• 2. 小児および思春期における遺伝性再生不良性貧血 inherited aplastic anemia in children and adolescents
• 3. アシュケナージ系ユダヤ人集団における遺伝的疾患の出生前スクリーニング prenatal screening for genetic disease in the ashkenazi jewish population
• 4. 小児および思春期における自己免疫性溶血性貧血 autoimmune hemolytic anemia in children and adolescents
• 5. ナイミーヘン染色体不安定症候群 nijmegen breakage syndrome

English Journal

• A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.

• Voter AF1, Manthei KA2, Keck JL3.
• Journal of biomolecular screening.J Biomol Screen.2016 Jul;21(6):626-33. doi: 10.1177/1087057116635503. Epub 2016 Mar 8.
• Induction of the Fanconi anemia (FA) DNA repair pathway is a common mechanism by which tumors evolve resistance to DNA crosslinking chemotherapies. Proper execution of the FA pathway requires interaction between the FA complementation group M protein (FANCM) and the RecQ-mediated genome instability
• PMID 26962873

• DNA REPAIR. Drugging DNA repair.

• Jackson SP1, Helleday T2.
• Science (New York, N.Y.).Science.2016 Jun 3;352(6290):1178-9. doi: 10.1126/science.aab0958.
• PMID 27257245

• FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice.

• Sun X1, Brieño-Enríquez MA1, Cornelius A1, Modzelewski AJ2, Maley TT1, Campbell-Peterson KM1, Holloway JK1, Cohen PE3.
• Chromosoma.Chromosoma.2016 Jun;125(2):237-52. doi: 10.1007/s00412-015-0549-2. Epub 2015 Oct 21.
• Fancj, the gene associated with Fanconi anemia (FA) Complementation Group J, encodes a DNA helicase involved in homologous recombination repair and the cellular response to replication stress. FANCJ functions in part through its interaction with key DNA repair proteins, including MutL homolog-1 (MLH
• PMID 26490168

Japanese Journal

• A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

• MEETEI AR
• Nat Genet 37, 958-963, 2005
• NAID 80017815909

• SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein

• OTSUKI T.
• Biochem. Biophys. Res. Commun. 265, 630-635, 1999
• NAID 80010789960

Related Links

• Fanconi anemia, complementation groups [FANC] | HUGO Gene ...

Genes encoding proteins that are supposed to function in the FA pathway, but without any patients identified to date who carry mutations in these ... FANCA, Fanconi anemia, complementation group A, FACA, FANCH, FAA, FA-H, FAH, 16q24.3 ...

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★リンクテーブル★

リンク元	「ファンコニ貧血相補群タンパク質」
関連記事	「group」「grouping」「complementation」「Fanconi」「grouped」

「ファンコニ貧血相補群タンパク質」

　　[★]

英

Fanconi anemia complementation group protein

「group」

　　[★]

• n.

• 集団、グループ、(動物)群れ、(分類学)群、(化学)基

• v.

• 分類する、グループ化する

関

assortment、categorization、categorize、category、class、classification、classifier、classify、cluster、collective、grouping、herd、mass、population、sort、swarm、systematization、typing

　 　 　 　 　 　

「grouping」

　　[★]

• n.

• 分類、グルーピング、グループ化、群化

関

assortment、categorization、categorize、category、class、classification、classifier、classify、group、grouped、sort、systematization、typing

　 　 　

「complementation」

　　[★]

• 相補性、補完

関

complement、complementarity、complementary

　

「Fanconi」

　　[★]

ファンコニー、ファンコニ、ファンコーニ

「grouped」

　　[★]

• adj.

• 群化の

関

grouping