CDPジアシルグリセロール・イノシトール-3-ホスファチジルトランスフェラーゼ
- 関
- phosphatidylinositol synthase
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- an optically inactive alcohol that is a component of the vitamin B complex
PrepTutorEJDIC
- carbonの化学記号
- certificate of deposit / (また『C.D.』)Civil Defense民間防衛
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/04 10:11:24」(JST)
[Wiki en表示]
CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
Identifiers |
EC number |
2.7.8.11 |
CAS number |
9027-01-4 |
Databases |
IntEnz |
IntEnz view |
BRENDA |
BRENDA entry |
ExPASy |
NiceZyme view |
KEGG |
KEGG entry |
MetaCyc |
metabolic pathway |
PRIAM |
profile |
PDB structures |
RCSB PDB PDBe PDBsum |
Gene Ontology |
AmiGO / EGO |
Search |
PMC |
articles |
PubMed |
articles |
NCBI |
proteins |
|
In enzymology, a CDP-diacylglycerol—inositol 3-phosphatidyltransferase (EC 2.7.8.11) is an enzyme that catalyzes the chemical reaction
- CDP-diacylglycerol + myo-inositol CMP + phosphatidyl-1D-myo-inositol
Thus, the two substrates of this enzyme are CDP-diacylglycerol and myo-inositol, whereas its two products are CMP and phosphatidyl-1D-myo-inositol.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase. Other names in common use include CDP-diglyceride-inositol phosphatidyltransferase, phosphatidylinositol synthase, CDP-diacylglycerol-inositol phosphatidyltransferase, CDP-diglyceride:inositol transferase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol, 3-phosphatidyltransferase, CDP-DG:inositol transferase, cytidine diphosphodiglyceride-inositol phosphatidyltransferase, CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase, CDP-diglyceride-inositol transferase, cytidine diphosphoglyceride-inositol phosphatidyltransferase, and cytidine diphosphoglyceride-inositol transferase. This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system.
References
- Bleasdale JE, Wallis P, MacDonald PC, Johnston JM (1979). "Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue". Biochim. Biophys. Acta. 575 (1): 135–47. doi:10.1016/0005-2760(79)90139-5. PMID 41587.
- Prottey C, Hawthorne JN (1967). "The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas". Biochem. J. 105 (1): 379–92. PMC 1198310. PMID 4293959.
- Salway JG, Harwood JL, Kai M, White GL, Haworne JN (1968). "Enzymes of phosphoinositide metabolism during rat brain development". J. Neurochem. 15 (3): 221–6. doi:10.1111/j.1471-4159.1968.tb06200.x. PMID 4295616.
- Takenawa T, Egawa K (1977). "CDP-diglyceride:inositol transferase from rat liver. Purification and properties". J. Biol. Chem. 252 (15): 5419–23. PMID 18462.
UpToDate Contents
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English Journal
- Rab10 GTPase regulates ER dynamics and morphology.
- English AR, Voeltz GK.SourceDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, 80309, USA.
- Nature cell biology.Nat Cell Biol.2013 Feb;15(2):169-78. doi: 10.1038/ncb2647. Epub 2012 Dec 23.
- We have identified Rab10 as an ER-specific Rab GTPase that regulates ER structure and dynamics. We show that Rab10 localizes to the ER and to dynamic ER-associated structures that track along microtubules and mark the position of new ER tubule growth. Rab10 depletion or expression of a Rab10 GDP-loc
- PMID 23263280
- Molecular interactions of natural and synthetic steroids in female hamsters' flank organs.
- Cabeza M, Naranjo B, Heuze Y, Sánchez A, Hernández M, Sainz T, Bratoeff E.SourceDepartment of Biological Systems and Animal Production Metropolitan University-Xochimilco, Mexico D.F., Mexico. marisa@correo.xoc.uam.mx
- Journal of dermatological science.J Dermatol Sci.2012 May;66(2):119-26. doi: 10.1016/j.jdermsci.2012.02.014. Epub 2012 Mar 3.
- BACKGROUND: The initial step of steroidal action on target cells is gene activation; therefore, the quantification of mRNA is a direct method for comparing the role of different steroids in the skin.OBJECTIVE: This study demonstrated the role of several steroids on the mRNA expression encoding for d
- PMID 22464229
Related Links
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- EC number 2.7.8.11 Systematic name CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase Recommended name CDP-diacylglycerol-inositol 3-phosphatidyltransferase Synonyms CDP-DG:inositol transferase CDP ...
Related Pictures
![Figure 2: Catalytic reactions of IPCT](https://1mg.info/0/4/p/0613.jpg)
![Phosphatidyl- myo- inositol Metabolism](https://1mg.info/0/4/p/0614.jpg)
![cdp diacylglycerol and inositol by cdp](https://1mg.info/0/4/p/0615.jpg)
![inositol cmp cdp diacylglycerol inositol 3](https://1mg.info/0/4/p/0617.jpg)
![PBB GE CDIPT 201253 s at tn.png](https://1mg.info/0/4/p/0618.jpg)
★リンクテーブル★
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- 関
- CDP-diacylglycerol-inositol 3-phosphatidyltransferase
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- 英
- CDP-diacylglycerol-inositol 3-phosphatidyltransferase
- 関
- ホスファチジルイノシトール合成酵素
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[★]
[★]
- 関
- cytidine diphosphate
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ジアシルグリセロール。DG DAG
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イノシトール
- 関
- myoinositol