頚動脈ステント留置術, carotid angioplasty with stent, carotid artery stenting
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
PrepTutorEJDIC
- Organization of Central American States 米中央州機構
- carbonの化学記号
- California
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/06 21:44:03」(JST)
wiki ja
wiki en
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 頸動脈ステントおよびその合併症 carotid artery stenting and its complications
- 2. 頸動脈内膜剥離術および頸動脈ステント留置術の麻酔 anesthesia for carotid endarterectomy and carotid stenting
- 3. 症候性頸動脈アテローム性動脈硬化症のマネージメント management of symptomatic carotid atherosclerotic disease
- 4. Management of asymptomatic carotid atherosclerotic disease
- 5. 頸動脈内膜剥離術の合併症 complications of carotid endarterectomy
English Journal
- A methylation-blocked cascade amplification strategy for label-free colorimetric detection of DNA methyltransferase activity.
- Zhao Y1, Chen F2, Lin M2, Fan C3.Author information 1Key Laboratory of Biomedical Information Engineering of Education Ministry, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China; Division of Physical Biology, and Bioimaging Center, Shanghai Synchrotron Radiation Facility, CAS Key Laboraotory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, PR China. Electronic address: yxzhao@mail.xjtu.edu.cn.2Key Laboratory of Biomedical Information Engineering of Education Ministry, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China.3Division of Physical Biology, and Bioimaging Center, Shanghai Synchrotron Radiation Facility, CAS Key Laboraotory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, PR China. Electronic address: fchh@sinap.ac.cn.AbstractDNA methyltransferase (MTase), catalyzing DNA methylation in both eukaryotes and prokaryotes, is closely related with cancer and bacterial diseases. Although there are various methods focusing on DNA MTase detection, most of them share common defects such as complicated setup, laborious operation and requirement of expensive analytical instruments. In this work, a simple strategy based on methylation-blocked cascade amplification is developed for label-free colorimetric assay of MTase activity. When DNA adenine methylation (Dam) MTase is introduced, the hairpin probe is methylated. This blocks the amplified generation of G-riched DNAzyme by nicking endonuclease and DNA polymerase, and inhibits the DNAzyme-catalyzed colorimetric reaction. Contrarily, an effective colorimetric reaction is initiated and high color signal is clearly observed by the naked eye in the absence of Dam MTase. A satisfying sensitivity and high selectivity are readily achieved within a short assay time of 77min, which are superior to those of some existing approaches. Additionally, the application of the sensing system in human serum is successfully verified with good recovery and reproducibility, indicating great potential for the practicality in high concentrations of interfering species. By using several anticancer and antimicrobial drugs as model, the inhibition of Dam MTase is well investigated. Therefore, the proposed method is not only promising and convenient in visualized analysis of MTase, but also useful for further application in fundamental biological research, early clinical diagnosis and drug discovery.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Apr 15;54:565-70. doi: 10.1016/j.bios.2013.11.055. Epub 2013 Nov 26.
- DNA methyltransferase (MTase), catalyzing DNA methylation in both eukaryotes and prokaryotes, is closely related with cancer and bacterial diseases. Although there are various methods focusing on DNA MTase detection, most of them share common defects such as complicated setup, laborious operation an
- PMID 24333567
- The unfolding of G-quadruplexes and its adverse effect on DNA-gold nanoparticles-based sensing system.
- Cheng S, Zheng B, Wang M, Ge X, Zhao Q, Liu W, Lam MH.Author information CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China and USTC-CityU Joint Advanced Research Center, Suzhou, PR China; Department of Biology and Chemistry, City University of Hong Kong and USTC-CityU Joint Advanced Research Center, Suzhou, PR China.AbstractThe adsorption of DNAs in G-quadruplex solution onto 13 nm gold nanoparticles (AuNPs) was studied through monitoring of the localized surface plasmon resonance (LSPR) absorbance of 13 nm AuNPs at 520 and 650 nm (A650/A520) in the solutions of three widely studied guanine-rich sequences, TBA(5'-GGTTGGTGTGGTTGG-3'), PW17(5'-GGGTAGGGCGGGTTGGG-3'), and PSO (5'-GGGTTAGGGTTAGGGTTAGGG-3'). It was found that the degree of adsorption of DNAs in Pb(2+) stabilized G-quadruplex (G-Pb(2+)) solutions is up to 93% after more than 5h of incubation. Furthermore, the lead concentrations in the solutions containing G-quadruplex and AuNP were analyzed by an inductively coupled plasma atomic emission spectrometer. The results showed that Pb(2+) had been released from the G-quadruplexes, which means the G-quadruplexes may be unfolded in the presence of AuNP. This interaction between G-quadruplexes and AuNP demonstrated that long time incubation between DNAs and AuNPs would possibly make it unable to distinguish G-quadruplex from ssDNA. Thus, a biosensing system consisting of PW17 and AuNPs was developed to detect Pb(2+). It was found that the LSPR responses at A650/A520 were sensitive to [Pb(2+)]. However, the sensitivity of the system was interfered by the potential unfolding of PW17-Pb(2+) in the presence of AuNPs. This unexpected adverse effect of AuNPs on DNA-based biosensors should be taken into consideration in the future development of biosensing systems that are based on ssDNA aptamers and unmodified AuNPs.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Mar 15;53:479-85. doi: 10.1016/j.bios.2013.10.016. Epub 2013 Oct 24.
- The adsorption of DNAs in G-quadruplex solution onto 13 nm gold nanoparticles (AuNPs) was studied through monitoring of the localized surface plasmon resonance (LSPR) absorbance of 13 nm AuNPs at 520 and 650 nm (A650/A520) in the solutions of three widely studied guanine-rich sequences, TBA(5'-GGTTG
- PMID 24211461
- Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.
- Ge Z1, Chen Q2, Osada K3, Liu X4, Tockary TA2, Uchida S4, Dirisala A5, Ishii T5, Nomoto T5, Toh K4, Matsumoto Y4, Oba M6, Kano MR7, Itaka K4, Kataoka K8.Author information 1Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, China.2Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.3Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan; Japan Science and Technology Agency, PRESTO, Japan. Electronic address: osada@bmw.t.u-tokyo.ac.jp.4Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.5Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.6Department of Molecular Medicinal Sciences, Division of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.7Department of Pharmaceutical Biomedicine, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsuhima-Naka, Kita-ku, Okayama 700-8530, Japan.8Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan; Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan; Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. Electronic address: kataoka@bmw.t.u-tokyo.ac.jp.AbstractAdequate retention in systemic circulation is the preliminary requirement for systemic gene delivery to afford high bioavailability into the targeted site. Polyplex micelle formulated through self-assembly of oppositely-charged poly(ethylene glycol) (PEG)-polycation block copolymer and plasmid DNA has gained tempting perspective upon its advantageous core-shell architecture, where outer hydrophilic PEG shell offers superior stealth behaviors. Aiming to promote these potential characters toward systemic applications, we strategically introduced hydrophobic cholesteryl moiety at the ω-terminus of block copolymer, anticipating to promote not only the stability of polyplex structure but also the tethered PEG crowdedness. Moreover, Mw of PEG in the PEGylated polyplex micelle was elongated up to 20 kDa for expecting further enhancement in PEG crowdedness. Furthermore, cyclic RGD peptide as ligand molecule to integrin receptors was installed at the distal end of PEG in order for facilitating targeted delivery to the tumor site as well as promoting cellular uptake and intracellular trafficking behaviors. Thus constructed cRGD conjugated polyplex micelle with the elevated PEG shielding was challenged to a modeled intractable pancreatic cancer in mice, achieving potent tumor growth suppression by efficient gene expression of antiangiogenic protein (sFlt-1) at the tumor site.
- Biomaterials.Biomaterials.2014 Mar;35(10):3416-26. doi: 10.1016/j.biomaterials.2013.12.086. Epub 2014 Jan 15.
- Adequate retention in systemic circulation is the preliminary requirement for systemic gene delivery to afford high bioavailability into the targeted site. Polyplex micelle formulated through self-assembly of oppositely-charged poly(ethylene glycol) (PEG)-polycation block copolymer and plasmid DNA h
- PMID 24439417
Japanese Journal
- p130Casを介する細胞のメカノ機能と恒常性の制御 (第1土曜特集 メカノバイオロジーからメカノメディシンへ) -- (メカノセンシング/シグナリング機構)
- 医学のあゆみ 257(10), 1031-1036, 2016-06-04
- NAID 40020838646
- NHK文研フォーラム2016 : 「これからのテレビ」を巡る動向を整理するVol.8 : 2016年1月-4月
- 放送研究と調査 66(6), 23-48, 2016-06
- NAID 110010036960
- H∞ Structured Controller Synthesis Applied to Flight Controller of QTW-UAV using Meta-Heuristic Particle Swarm Optimization
- システム制御情報学会研究発表講演会講演論文集 60, 5p, 2016-05-25
- NAID 40020836687
Related Pictures
★リンクテーブル★
| リンク元 | 「頚動脈ステント留置術」「carotid artery stenting」 |
| 拡張検索 | 「CAS protein」「FCAS」「CCAS」「ACAS」 |
| 関連記事 | 「C」「CA」 |
「頚動脈ステント留置術」
適応
- ガイドラインより(参考1)
- 内頚動脈狭窄症において、頚動脈内膜剥離術の危険因子を持つ症例に対して､頚動脈ステント留置術を行うことが奨められる(グレードB)｡(参考1)
SAPPHIRE研究で規定されたCEA危険因子（少なくとも1つが該当）
- 参考1
- 心臓疾患(うっ血性心不全､冠動脈疾患､開胸手術が必要など)
- 重篤な呼吸器疾患
- 対側頚動脈閉塞
- 対側喉頭神経麻痺
- 頚部直達手術､または頚部放射線治療の既往
- CEA再狭窄例
- 80歳以上
参考
- 1. 脳卒中治療ガイドライン2009
「carotid artery stenting」
「CAS protein」
「FCAS」
[★] 家族性感冒自己炎症性症候群 familial cold autoinflammatory syndrome
「CCAS」
[★] 小脳性認知情動症候群 cerebellar cognitive affective syndrome
「ACAS」
「C」
- 炭素 carbon
- シトシン cytosine
- システイン cysteine
- シチジン
- セルシウス度 摂氏 degrees Celsius degree C
- 産婦人科領域で「子宮外頚 子宮外頚部 exocervix」を表現するための略語
「CA」
- カテコールアミン catecholamine
- 癌 cancer carcinoma
- 炭酸脱水酵素 carbonic anhydrase
- 生活年齢 chronological age
- 糖鎖抗原 carbohydrate antigen