細胞アポトーシス感受性タンパク質
- 関
- CAS protein
WordNet
- relating to cells; "cellular walls"; "cellular physiology"
- characterized by or divided into or containing cells or compartments (the smallest organizational or structural unit of an organism or organization); "the cellular construction of a beehive"; "any effective opposition to a totalitarian regime must be secretive and cellular"
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- the state of being susceptible; easily affected (同)susceptibleness
- a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animals survival (同)programmed_cell_death, caspase-mediated cell death
PrepTutorEJDIC
- 蛋白(たんばく)質
- 〈U〉(…に)(感染し)やすいこと,敏感《+to+名》 / 《複数形で》(傷つきやすい)感情
- 細胞の,細胞質の,細胞状の / 小室(小区画)のある / (生地など)目の透いている
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/29 18:11:18」(JST)
[Wiki en表示]
CSE1 chromosome segregation 1-like (yeast) |
Identifiers |
Symbol |
CSE1L |
Entrez |
1434 |
HUGO |
2431 |
OMIM |
601342 |
RefSeq |
NM_001316 |
UniProt |
P55060 |
Other data |
Locus |
Chr. 20 q13 |
The cellular apoptosis susceptibility protein (CAS) is an exportin which in the nucleus is bound to RanGTP.
See also
- Nuclear_pore#Import_of_proteins
External links
- Cellular Apoptosis Susceptibility Protein at the US National Library of Medicine Medical Subject Headings (MeSH)
Cell cycle proteins
|
|
Cyclin |
- A (A1, A2)
- B (B1, B2, B3)
- D (D1, D2, D3)
- E (E1, E2)
|
|
CDK |
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10
- CDK-activating kinase
|
|
CDK inhibitor |
- INK4a/ARF (p14arf/p16, p15, p18, p19)
- cip/kip (p21, p27, p57)
|
|
P53 p63 p73 family |
|
|
Phases and
checkpoints |
Interphase |
- G1 phase
- S phase
- G2 phase
|
|
M phase |
- Mitosis (Preprophase
- Prophase
- Prometaphase
- Metaphase
- Anaphase
- Telophase)
- Cytokinesis
|
|
Cell cycle checkpoints |
- Restriction point
- Spindle checkpoint
- Postreplication checkpoint
|
|
Other cellular phases |
- Apoptosis
- G0 phase
- Meiosis
|
|
|
B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)
|
|
UpToDate Contents
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English Journal
- Signaling the mitochondrial unfolded protein response.
- Pellegrino MW, Nargund AM, Haynes CM.SourceCell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
- Biochimica et biophysica acta.Biochim Biophys Acta.2013 Feb;1833(2):410-6. doi: 10.1016/j.bbamcr.2012.02.019. Epub 2012 Mar 14.
- Mitochondria are compartmentalized organelles essential for numerous cellular functions including ATP generation, iron-sulfur cluster biogenesis, nucleotide and amino acid metabolism as well as apoptosis. To promote biogenesis and proper function, mitochondria have a dedicated repertoire of molecula
- PMID 22445420
- Nrf2-induced anti-apoptotic Bcl-xL protein enhances cell survival and drug resistance.
- Niture SK, Jaiswal AK.SourceDepartment of Pharmacology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201.
- Free radical biology & medicine.Free Radic Biol Med.2012 Dec 27. pii: S0891-5849(12)01864-3. doi: 10.1016/j.freeradbiomed.2012.12.014. [Epub ahead of print]
- Nuclear transcription factor Nrf2, binds with antioxidant response element (ARE) in the promoter regions of cytoprotective genes leading to its increased expression and cellular protection. In the present study, we investigated the role of Nrf2 in the regulation of anti-apoptotic Bcl-xL protein and
- PMID 23275004
- Host Immune Defense Peptide LL-37 Activates Caspase-Independent Apoptosis and Suppresses Colon Cancer.
- Ren SX, Cheng AS, To KF, Tong JH, Li MS, Shen J, Wong CC, Zhang L, Chan RL, Wang XJ, Ng SS, Chiu LC, Marquez VE, Gallo RL, Chan FK, Yu J, Sung JJ, Wu WK, Cho CH.SourceAuthors' Affiliations: School of Biomedical Sciences; Institute of Digestive Disease, LKS Institute of Health and Department of Medicine & Therapeutics; Departments of Anatomical & Cellular Pathology and Surgery; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong; Laboratory of Medicinal Chemistry, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, Maryland; and Division of Dermatology, University of California, San Diego, California.
- Cancer research.Cancer Res.2012 Dec 15;72(24):6512-23. doi: 10.1158/0008-5472.CAN-12-2359. Epub 2012 Oct 24.
- Cathelicidins are a family of bacteriocidal polypeptides secreted by macrophages and polymorphonuclear leukocytes (PMN). LL-37, the only human cathelicidin, has been implicated in tumorigenesis, but there has been limited investigation of its expression and function in cancer. Here, we report that L
- PMID 23100468
Japanese Journal
- The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.
- Increased susceptibility to tumor necrosis factor-α in butyric acid-induced apoptosis is caused by downregulation of cFLIP expression in Jurkat T cells
- 口腔へん平上皮癌細胞のデスレセプター誘導アポトーシス感受性に対する分子標的治療薬の影響
Related Links
- The cellular apoptosis susceptibility (CSE1L/CAS) protein is the human homologue of the yeast chromosome segregation gene product, CSE1. 19 CSE1L (or CAS) can regulate apoptosis induced by interferon-γ, 20 chemotherapeutic drugs, ...
- The cellular apoptosis susceptibility (CAS) protein is regarded as a proliferation-associated protein that associates with tumour proliferation as it associates with microtubule and functions in the mitotic spindle checkpoint. However ...
Related Pictures
★リンクテーブル★
[★]
細胞アポトーシス感受性タンパク質
- 関
- cellular apoptosis susceptibility protein
[★]
- 英
- cellular apoptosis susceptibility protein、CAS protein
[★]
- (~に)感じやすいこと、感受性(to)。(病気などに)罹患しやすいこと(to)
- (傷つきやすい)感情
[★]
- 関
- cell、cell-mediated、cellularity、cyto