WordNet

the act of terminating a project or procedure before it is completed; "I wasted a year of my life working on an abort"; "he sent a short message requesting an abort due to extreme winds in the area"
cease development, die, and be aborted; "an aborting fetus"
terminate a pregnancy by undergoing an abortion
terminate before completion; "abort the mission"; "abort the process running on my computer"
a human fetus whose weight is less than 0.5 kilogram when removed or expelled from the mothers body
an aerobic Gram-negative coccobacillus that causes brucellosis; can be used as a bioweapon

PrepTutorEJDIC

流産する / 〈動植物や器官などが〉十分に発育しない / 〈計画が〉失敗する,中止となる / 〈胎児〉'を'流産させる / 〈計画など〉'を'中止する

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/04/05 21:36:47」(JST)

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Brucella abortus is a Gram-negative proteobacterium in the family Brucellaceae, and is one of the causative agents of brucellosis. The rod-shaped pathogen is classified under the domain Bacteria.^[1] The prokaryotic B. abortus, is spore-forming, nonmotile and aerobic.^[2]

Brucella abortus enters phagocytes that invade human and animal defenses which in turn, cause chronic disease in the host. The liver and spleen are the affected areas of the body.^[3] Farm workers and veterinarians are the highest risk individuals for acquiring the disease. Swine, goats, sheep, and cattle are a few of the reservoirs for the disease.^[4] B. abortus causes abortion and infertility in adult cattle, and is a zoonosis which is present worldwide.^[5] Humans are commonly infected after drinking unpasteurized milk from affected animals.^[6]

The incubation period for the disease can range from 2 weeks to 1 year. Once symptoms begin to show, the host will be sick anywhere from 5 days to 5 months, depending on severity of illness. A few of the symptoms of brucellosis include: fever, chills, headache, backache, and weight loss. As with any disease, there can be serious complications; endocarditis and liver abscess are a couple of complications for brucellosis.^[7]

B. abortus also affects bison.^[8]

References

^ "National Institutes of Health (NIH)". National Institutes of Health (NIH). Retrieved 2017-10-25.
^ "CDC Works 24/7". Centers for Disease Control and Prevention. 2017-10-24. Retrieved 2017-10-25.
^ "CDC Works 24/7". Centers for Disease Control and Prevention. 2017-10-24. Retrieved 2017-10-25.
^ "CDC Works 24/7". Centers for Disease Control and Prevention. 2017-10-24. Retrieved 2017-10-25.
^ Dorneles, EM; Sriranganathan, N; Lage, AP (8 July 2015). "Recent advances in Brucella abortus vaccines". Veterinary research. 46: 76. doi:10.1186/s13567-015-0199-7. PMC 4495609 . PMID 26155935.
^ Scott, PR; Penny, CD; Macrae, A, eds. (2011). "Brucellosis". Cattle Medicine. London: Manson Pub. p. 34. ISBN 978-1840766110.
^ "microbewiki". microbewiki.kenyon.edu. Retrieved 2017-10-25.
^ Lott, Dale F. (2002). American bison: a natural history. Berkeley: University of California Press. p. 109. ISBN 978-0520233386.

External links

UpToDate Contents

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1. ブルセラ菌の微生物学、疫学、および病因 microbiology epidemiology and pathogenesis of brucella
2. 好中球減少症における感染の原因 infectious causes of neutropenia
3. 敗血症性滑液包炎 septic bursitis
4. 慢性疾患／炎症時の貧血 anemia of chronic disease inflammation
5. 犬および猫以外のペットからの人畜共通感染症 zoonoses from pets other than dogs and cats

English Journal

Monocyte-derived macrophages from Zebu (Bos taurus indicus) are more efficient to control Brucella abortus intracellular survival than macrophages from European cattle (Bos taurus taurus).

Macedo AA, Costa EA, Silva AP, Paixão TA, Santos RL.SourceDepartamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Brazil.
Veterinary immunology and immunopathology.Vet Immunol Immunopathol.2013 Feb 15;151(3-4):294-302. doi: 10.1016/j.vetimm.2012.12.001. Epub 2012 Dec 8.
Brucellosis is one of the most important zoonotic diseases in the world. Considering its strict zoonotic nature, understanding of the pathogenesis and immunity of Brucella spp. in natural animal hosts is essential to prevent human infections. Natural resistance against brucellosis has been demonstra
PMID 23270587

Link between Geographical Origin and Occurrence of Brucella abortus Biovars in Cow and Water Buffalo Herds.

Borriello G, Peletto S, Lucibelli MG, Acutis PL, Ercolini D, Galiero G.SourceIstituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Italy.
Applied and environmental microbiology.Appl Environ Microbiol.2013 Feb;79(3):1039-43. doi: 10.1128/AEM.02887-12. Epub 2012 Nov 26.
Sixty-three Brucella isolates from water buffaloes and cattle slaughtered within the Italian national plan for brucellosis control were characterized by multiple-locus variable-number tandem repeat analysis (MLVA). Genotyping indicated a strong influence of geographic origin on the Brucella abortus
PMID 23183984

Intracellularly Induced Cyclophilins Play an Important Role in Stress Adaptation and Virulence of Brucella abortus.

Roset MS, García Fernández L, Delvecchio VG, Briones G.SourceInstituto de Investigaciones Biotecnológicas-Instituto Tecnológico de Chascomús (IIB-INTECH), Universidad Nacional de San Martín (UNSAM)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Infection and immunity.Infect Immun.2013 Feb;81(2):521-30. doi: 10.1128/IAI.01125-12. Epub 2012 Dec 10.
Brucella is an intracellular bacterial pathogen that causes the worldwide zoonotic disease brucellosis. Brucella virulence relies on its ability to transition to an intracellular lifestyle within host cells. Thus, this pathogen must sense its intracellular localization and then reprogram gene expres
PMID 23230297

Japanese Journal

Differential diagnosis of Brucella abortus by real-time PCR based on a single-nucleotide polymorphisms

The journal of veterinary medical science 78(4), 557-562, 2016-04
NAID 40020843371

ブルセラ・アボルタス菌の細胞内増殖を制御する新規宿主因子Yip1A

生化学 88(1), 139-143, 2016-02
NAID 40020753666

Protection efficacy of the Brucella abortus ghost vaccine candidate lysed by the N-terminal 24-amino acid fragment (GI24) of the 36-amino acid peptide PMAP-36 (porcine myeloid antimicrobial peptide 36) in murine models

Journal of Veterinary Medical Science advpub(0), 2016
NAID 130005158320

Related Pictures

★リンクテーブル★

国試過去問	「110A038」
リンク元	「ウシ流産菌」「B. abortus」
関連記事	「abort」

「110A038」

Brucella abortus
Scientific classification
Domain:	Bacteria
Phylum:	Proteobacteria
Class:	Alphaproteobacteria
Order:	Rhizobiales
Family:	Brucellaceae
Genus:	Brucella
Species:	B. abortus
Binomial name
	Brucella abortus; (Schmidt, 1901) Meyer and Shaw, 1920

　　[★]

60歳の男性。左下腿痛を主訴に来院した。2日前から誘因なく左下腿痛が出現した。昨日から悪寒と戦慄が出現したため受診した。既往に左下腿骨骨折があり、糖尿病による慢性腎不全で5年前から透析を受けている。体温 38.5℃。脈拍 84/分、整。血圧 130/70mmHg。左下腿に発赤、熱感および腫脹があり、軟部組織に握雪感を認める。赤沈 70mm/1時間。血液所見：赤血球 294万、Hb 7.7g/dL、白血球 25,100(桿状核好中球7%、分葉核好中球 72%、リンパ球6%、単球14%)。プロカルシトニン 3.0ng/mL(基準 0.05未満)。CRP 31mg/dL。左下腿エックス線写真(別冊No. 11Ａ)と左下腿CT(別冊No. 11Ｂ)とを別に示す。
原因菌として最も考えられるのはどれか。