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1. 造血幹細胞の概要overview of hematopoietic stem cells [show details]
…confers the potential to maintain long-term multilineage hematopoiesis throughout the lifespan of an individual. The concept that sustained hematopoiesis comes from multipotent stem cells derives from the observation …
2. 赤血球産生調節regulation of erythropoiesis [show details]
…disruption of the GATA2 gene leads to reduced primitive hematopoiesis in the yolk sac and embryonic death by day 10 to 11 . Definitive hematopoiesis in liver and bone marrow is profoundly reduced with loss …
3. 骨髄造血の制御regulation of myelopoiesis [show details]
…myeloid cells (granulocytes and monocytes) is a tightly regulated process. During steady-state hematopoiesis, approximately 10⁸ to 10⁹ of these cells are produced per hour in the bone marrow …
4. BおよびTリンパ球の正常な発生normal b and t lymphocyte development [show details]
…mice . Blood forming cells first appear in the yolk sac around day 16 of gestation, but yolk sac hematopoiesis is restricted to the production of primitive red cells, platelets, and monocyte/macrophage-like …
5. 未確定の潜在能をもつクローン性造血（CHIP）とクローン性造血の関連疾患clonal hematopoiesis of indeterminate potential chip and related disorders of clonal hematopoiesis [show details]
…Categories of CH include: Clonal hematopoiesis of indeterminate potential (CHIP) Clonal cytopenia of undetermined significance (CCUS) Aging-related clonal hematopoiesis (ARCH) CHIP, CCUS, and ARCH are …