小胞結合膜タンパク質3
- 関
- synaptobrevin 3、VAMP3
WordNet
- having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
- a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
- a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
- any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
- make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a thin pliable sheet of material
- a pliable sheet of tissue that covers or lines or connects the organs or cells of animals or plants (同)tissue layer
- a small anatomically normal sac or bladderlike structure (especially one containing fluid) (同)cyst
PrepTutorEJDIC
- 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
- 蛋白(たんばく)質
- (生物の)膜,皮膜
- 小嚢,小胞,小水(気)胞,小空胞
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/10/25 02:46:47」(JST)
[Wiki en表示]
Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion.
- VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neuromediator release.
- VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
- VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis.
- VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
- VAMP7 is found both in secretory granules and endosomes.
- VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
- VAMP4 is involved in transport from the Golgi.[1]
References
- ^ Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH (1999). "Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking". Mol. Biol. Cell. 10 (6): 1957–72. PMC 25394 . PMID 10359608. doi:10.1091/mbc.10.6.1957.
External links
- Vesicle-Associated Membrane Protein 1 at the US National Library of Medicine Medical Subject Headings (MeSH)
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Protein: cell membrane proteins (other than Cell surface receptor, enzymes, and cytoskeleton)
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| Arrestin |
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| Membrane-spanning 4A |
- MS4A1
- MS4A2
- MS4A3
- MS4A4A
- MS4A4E
- MS4A5
- MS4A6A
- MS4A6E
- MS4A7
- MS4A8B
- MS4A9
- MS4A10
- MS4A12
- MS4A13
- MS4A14
- MS4A15
- MS4A18
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| Myelin |
- Myelin basic protein
- Myelin proteolipid protein
- Myelin oligodendrocyte glycoprotein
- Myelin-associated glycoprotein
- Myelin protein zero
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| Pulmonary surfactant |
- Pulmonary surfactant-associated protein B
- Pulmonary surfactant-associated protein C
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| Tetraspanin |
- TSPAN1
- TSPAN2
- TSPAN3
- TSPAN4
- TSPAN5
- TSPAN6
- TSPAN7
- TSPAN8
- TSPAN9
- TSPAN10
- TSPAN11
- TSPAN12
- TSPAN13
- TSPAN14
- TSPAN15
- TSPAN16
- TSPAN17
- TSPAN18
- TSPAN19
- TSPAN20
- TSPAN21
- TSPAN22
- TSPAN23
- TSPAN24
- TSPAN25
- TSPAN26
- TSPAN27
- TSPAN28
- TSPAN29
- TSPAN30
- TSPAN31
- TSPAN32
- TSPAN33
- TSPAN34
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| Other/ungrouped |
- Calnexin
- LDL-receptor-related protein-associated protein
- Neurofibromin 2
- Presenilin
- HFE
- Phospholipid transfer proteins
- Dysferlin
- STRC
- OTOF
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|
see also other cell membrane protein disorders
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Membrane protein: vesicular transport proteins (TC 1F)
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| Synaptic vesicle |
| SNARE |
| Q-SNARE |
- Syntaxin
- STX1A
- STX1B
- STX2
- STX3
- STX4
- STX5
- STX6
- STX7
- STX8
- STX10
- STX11
- STX12
- STX16
- STX17
- STX18
- STX19
- Munc-18: STXBP1
- STXBP2
- STXBP3
- STXBP4
- STXBP5
- STXBP6
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| R-SNARE |
- Synaptobrevin/VAMP: VAMP1
- VAMP2
- VAMP3
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|
| Synaptotagmin |
- SYT1
- SYT2
- SYT3
- SYT4
- SYT5
- SYT6
- SYT7
- SYT8
- SYT9
- SYT10
- SYT11
- SYT12
- SYT13
- SYT14
- SYT15
- SYT16
- SYT17
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| Other |
|
|
| COPI |
- Coatomer
- COPA
- COPB1
- COPB2
- COPD/Archain
- COPE
- COPG
- COPG2
- COPZ1
- COPZ2
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| COPII |
- Coatomer
- SEC23A/SEC24A
- SEC13/SEC31
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| RME/Clathrin |
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| Caveolae |
- Caveolin (CAV1
- CAV2
- CAV3)
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| Other/ungrouped |
| Vesicle formation |
| Adaptor protein complex 1: |
- AP1AR
- AP1B1
- AP1G1
- AP1G2
- AP1M1
- AP1M2
- AP1S1
- AP1S2
- AP1S3
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| Adaptor protein complex 2: |
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
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| Adaptor protein complex 3: |
- AP3B1
- AP3B2
- AP3D1
- AP3M1
- AP3M2
- AP3S1
- AP3S2
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| Adaptor protein complex 4: |
|
|
|
|
|
| BLOC-1: |
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| BLOC-2: |
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| BLOC-3: |
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| Coats: |
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| Small GTPase |
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| Other |
- EHD protein family: EHD1
- EHD2
- EHD3
- EHD4
- Vacuolar protein sorting: VPS13B
- VPS33B
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|
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See also vesicular transport protein disorders
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Acetylcholine metabolism and transport modulators
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Enzyme
(modulators) |
| ChAT |
- Inhibitors: 1-(-Benzoylethyl)pyridinium
- 2-(α-Naphthoyl)ethyltrimethylammonium
- 3-Chloro-4-stillbazole
- 4-(1-Naphthylvinyl)pyridine
- Acetylseco hemicholinium-3
- Acryloylcholine
- AF64A
- B115
- BETA
- CM-54,903
- N,N-Dimethylaminoethylacrylate
- N,N-Dimethylaminoethylchloroacetate
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| AChE |
|
| BChE |
- Inhibitors: Affinine
- Affinisine
- Conodurine
- Cymserine
- Ladostigil
- Profenamine (ethopropazine)
- Rivastigmine
- Tacrine
- ZINC-12613047
- Many of the other AChE inhibitors listed above
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|
Transporter
(modulators) |
| CHT |
- Inhibitors: Hemicholinium-3 (hemicholine)
- Triethylcholine
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| VAChT |
|
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Release
(modulators) |
| Inhibitors |
- SNAP-25 inactivators: Botulinum toxin (A, C, E)
- VAMP inactivators: Botulinum toxin (B, D, F, G)
- Others: Bungarotoxins (β-bungarotoxin, γ-bungarotoxin)
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| Enhancers |
- LPHN agonists: α-Latrotoxin
- Others: Atracotoxin (e.g., robustoxin, versutoxin)
- Crotoxin
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|
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See also: Receptor/signaling modulators • Muscarinic acetylcholine receptor modulators • Nicotinic acetylcholine receptor modulators
|
UpToDate Contents
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English Journal
- Human herpesvirus 6 gM/gN complex interacts with v-SNARE in infected cells.
- Kawabata A1, Serada S2, Naka T2, Mori Y3.
- The Journal of general virology.J Gen Virol.2014 Dec;95(Pt 12):2769-77. doi: 10.1099/vir.0.069336-0. Epub 2014 Sep 10.
- Human herpesvirus 6 (HHV-6) glycoprotein M (gM) is an envelope glycoprotein that associates with glycoprotein N (gN), forming the gM/gN protein complex, in a similar manner to the other herpesviruses. Liquid chromatography-MS/MS analysis showed that the HHV-6 gM/gN complex interacts with the v-SNARE
- PMID 25209806
- Endosomal sorting of VAMP3 is regulated by PI4K2A.
- Jović M1, Kean MJ2, Dubankova A3, Boura E3, Gingras AC2, Brill JA4, Balla T5.
- Journal of cell science.J Cell Sci.2014 Sep 1;127(Pt 17):3745-56. doi: 10.1242/jcs.148809. Epub 2014 Jul 7.
- Specificity of membrane fusion in vesicular trafficking is dependent on proper subcellular distribution of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). Although SNARE complexes are fairly promiscuous in vitro, substantial specificity is achieved in cells owing to
- PMID 25002402
- Vesicle-associated membrane protein 2 (VAMP2) but Not VAMP3 mediates cAMP-stimulated trafficking of the renal Na+-K+-2Cl- co-transporter NKCC2 in thick ascending limbs.
- Caceres PS1, Mendez M2, Ortiz PA3.
- The Journal of biological chemistry.J Biol Chem.2014 Aug 22;289(34):23951-62. doi: 10.1074/jbc.M114.589333. Epub 2014 Jul 9.
- In the kidney, epithelial cells of the thick ascending limb (TAL) reabsorb NaCl via the apical Na(+)/K(+)/2Cl(-) co-transporter NKCC2. Steady-state surface NKCC2 levels in the apical membrane are maintained by a balance between exocytic delivery, endocytosis, and recycling. cAMP is the second messen
- PMID 25008321
Japanese Journal
- SNARE dynamics during melanosome maturation
- Ohbayashi Norihiko,Fukuda Mitsunori,大林 典彦
- Biochemical Society transactions 46(4), 911-917, 2018-08
- … During melanosome maturation, melanosome cargoes including melanogenic enzymes (e.g. tyrosinase) are transported from endosomes to immature melanosomes by membrane trafficking, which must require a membrane fusion process likely regulated by SNAREs [soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptors]. …
- NAID 120006542269
- <b>Syntaxin 6 is Involved in the Maintenance of Secretory Granules in Parotid Acinar Cells </b>
- Yokoyama Megumi,Katsumata-Kato Osamu,Fujita-Yoshigaki Junko
- International Journal of Oral-Medical Sciences 15(3-4), 67-73, 2017
- … Syntaxin 6 and vesicle associated membrane protein 4 (VAMP4) are detected in the membrane fractions of immature but not mature SGs, suggesting that syntaxin 6 and VAMP4 are transported from SGs to other organelles during the process of granule maturation. …
- NAID 130006894939
- 精巣上体通過中のマウス精子における細胞滴遊離メカニズムの検討
- 近藤 瑞穂,田島 淳史,石川 尚人,浅野 敦之
- 日本繁殖生物学会 講演要旨集 109(0), OR1-13-OR1-13, 2016
- … 他細胞では，PphnはSNARE複合体の構成因子であるVesicle-associated membrane protein（VAMP） 2と複合体を形成し，Ca<sup>2+</sup>依存性膜融合の制御に関与すると考えられている。 …
- NAID 130007024174
Related Links
- "Identification of a cellubrevin/vesicle associated membrane protein 3 homologue in human platelets." Bernstein A.M., Whiteheart S.W. Blood 93:571-579(1999) [PubMed] [Europe PMC] [Abstract] Cited for: "Cloning of human full , ...
- VAMP3 » Vesicle-associated membrane protein 3 (VAMP favorite label Protein also known as: Synaptobrevin-3. Gene name: VAMP3 Family name: Synaptobrevin Entry whose protein(s) existence is based on evidence at protein ...
★リンクテーブル★
[★]
- 関
- synaptobrevin 3、vesicle-associated membrane protein 3
[★]
- 英
- vesicle-associated membrane protein 3、VAMP3
- 関
- シナプトブレビン3
[★]
シナプトブレビン3
- 関
- VAMP3、vesicle-associated membrane protein 3
[★]
- 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる
- 仲間/友人などとして交際する(with)。一つにまとめる、連合する
- 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
- 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
- 連想によって心に浮かぶ言葉/思い、連想物
- 仲間の、同僚の。製紙機械員に次ぐ資格の
- 付随する、連想される
- 関
- accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union
[★]
- 関
- concomitant、erratic、erratically
- associate
[★]
[★]