- 関
- tumor progression
WordNet
- cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here" (同)raise, farm, produce
- come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts" (同)develop, produce, get, acquire
- become attached by or as if by the process of growth; "The tree trunks had grown together"
- become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"
- cause to grow or develop; "He grows vegetables in his backyard"
- increase in size by natural process; "Corn doesnt grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesnt grow much anymore"
- (biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children" (同)growing, maturation, development, ontogeny, ontogenesis
- (pathology) an abnormal proliferation of tissue (as in a tumor)
- a progression from simpler to more complex forms; "the growth of culture"
- something grown or growing; "a growth of hair"
- vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"
- an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm
PrepTutorEJDIC
- 『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)
- 〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)
UpToDate Contents
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English Journal
- Clinical and Histological Features of Multifocal Canalicular Adenomas of the Upper Lip.
- Siqueira CS, Fernandes KS, Vivas AP, Pinto DD Junior, Sousa SC.AbstractCanalicular adenoma (CA) is an uncommon benign salivary gland tumor that mostly occurs in the upper lip. Despite its benign nature, some patients may present multiple nodules and also microscopic growth that can be multifocal with foci of tumor within the adjacent gland. Microscopically, CA can be mistaken for a polymorphous low-grade adenocarcinoma (PLGA) or basal cell adenoma (BCA), and immunohistochemistry can be helpful in differentiating them. Two cases of canalicular adenoma showing tumor foci within the adjacent gland are described. Both cases occurred in the upper lip of white females aged 72 and 79 years. In addition to the histological multifocal aspect, one of the patients presented bi-lateral nodules. Histological examination of both lesions revealed interconnecting and branching canal-like structures composed by uniform columnar and sometimes cuboidal cells, partially encapsulated. Immunohistochemical analysis showed intense expression of cytokeratins (CK) 7, a weak reaction to CK14 and a negative reaction to vimentin. Upon the diagnosis of CA the lesions were excised. In conclusion, it is important to properly diagnose CA and differentiate its multifocal aspect from a malignant behavior.
- Brazilian dental journal.Braz Dent J.2014 Sep-Oct;24(5):542-546.
- Canalicular adenoma (CA) is an uncommon benign salivary gland tumor that mostly occurs in the upper lip. Despite its benign nature, some patients may present multiple nodules and also microscopic growth that can be multifocal with foci of tumor within the adjacent gland. Microscopically, CA can be m
- PMID 24474301
- Dynamic fluorescent imaging with indocyanine green for monitoring the therapeutic effects of photoimmunotherapy.
- Ali T1, Nakajima T, Sano K, Sato K, Choyke PL, Kobayashi H.Author information 1Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, 20892-1088, USA.AbstractA new type of monoclonal antibody (mAb)-based, highly specific phototherapy (photoimmunotherapy; PIT) that uses a near-infrared (NIR) phthalocyanine dye, IRDye700DX (IR700) conjugated with an mAb, has recently been described. NIR light exposure leads to immediate, target-selective necrotic cell death. However, tumor shrinkage takes several days to occur, making it difficult to detect earlier changes in the tumor. In this study, Panitumumab targeting the epidermal growth factor receptor (EGFR1) conjugated to IR700 was used to treat EGFR-expressing A431 tumor cells and in vivo xenografts. PIT was performed at varying doses of NIR light (10, 30, 50 and 100 J cm(-2) ) in xenograft tumors in mice. Indocyanine green (ICG) dynamic imaging was evaluated for monitoring cytotoxic effects for the first hour after PIT. Our results demonstrated a statistical difference (p < 0.05) in ICG intensity between control and PIT treated tumors in the higher light exposure groups (50 J cm(-2) : 2.94 ± 0.35 vs 5.22 ± 0.92, p = 0.02; and 100 J cm(-2) : 3.56 ± 0.96 vs 5.71 ± 1.43, p = 0.008) as early as 20 min post ICG injection. However, no significant difference (p > 0.05) in ICG intensity between control and PIT treated tumors was evident in the lower light exposure group at any time points up to 60 min (10 J cm(-2) : 1.92 ± 0.49 vs 1.71 ± 0.3, p = 0.44; and 30 J cm(-2) : 1.57 ± 0.35 vs 2.75 ± 0.59, p = 0.07). Similarly, the retention index (background to corrected uptake ratio of ICG) varied with light exposure. In conclusion, ICG may serve as a potential indicator of acute cytotoxic effects of mAb-IR700-induced PIT even before morphological changes can be seen in targeted tumors. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
- Contrast media & molecular imaging.Contrast Media Mol Imaging.2014 Jul;9(4):276-82. doi: 10.1002/cmmi.1570.
- A new type of monoclonal antibody (mAb)-based, highly specific phototherapy (photoimmunotherapy; PIT) that uses a near-infrared (NIR) phthalocyanine dye, IRDye700DX (IR700) conjugated with an mAb, has recently been described. NIR light exposure leads to immediate, target-selective necrotic cell deat
- PMID 24706611
- Design and validation of a fiber optic point probe instrument for therapy guidance and monitoring.
- Xie H1, Xie Z1, Mousavi M1, Bendsoe N2, Brydegaard M1, Axelsson J1, Andersson-Engels S1.Author information 1Lund University, Department of Physics, P.O. Box 118, SE-221 00 Lund, Sweden.2Skåne University Hospital, Department of Dermatology and Venereology, Lasarettsgatan 15, SE-221 85 Lund, Sweden.AbstractABSTRACT. Optical techniques for tissue diagnostics currently are experiencing tremendous growth in biomedical applications, mainly due to their noninvasive, inexpensive, and real-time functionality. Here, we demonstrate a hand-held fiber optic probe instrument based on fluorescence/reflectance spectroscopy for precise tumor delineation. It is mainly aimed for brain tumor resection guidance with clinical adaptation to minimize the disruption of the standard surgical workflow and is meant as a complement to the state-of-the-art fluorescence surgical microscopy technique. Multiple light sources with fast pulse modulation and detection enable precise quantification of protoporphyrin IX (PpIX), tissue optical properties, and ambient light suppression. Laboratory measurements show the system is insensitive to strong ambient light. Validation measurements of tissue phantoms using nonlinear least squares support vector machines (LS-SVM) regression analysis demonstrate an error of <5% for PpIX concentration ranging from 400 to 1000 nM, even in the presence of large variations in phantom optical properties. The mean error is 3% for reduced scattering coefficient and 5% for blood concentration. Diagnostic precision of 100% was obtained by LS-SVM classification for in vivo skin tumors with topically applied 5-aminolevulinic acid during photodynamic therapy. The probe could easily be generalized to other tissue types and fluorophores for therapy guidance and monitoring.
- Journal of biomedical optics.J Biomed Opt.2014 Jul 1;19(7):71408. doi: 10.1117/1.JBO.19.7.071408.
- ABSTRACT. Optical techniques for tissue diagnostics currently are experiencing tremendous growth in biomedical applications, mainly due to their noninvasive, inexpensive, and real-time functionality. Here, we demonstrate a hand-held fiber optic probe instrument based on fluorescence/reflectance spec
- PMID 24623193
Japanese Journal
- 福井 崇将,若月 悠祐,豊 洋次郎 [他]
- 胸部外科 = The Japanese journal of thoracic surgery 68(3), 193-196, 2015-03
- NAID 40020369008
- Mechanism responsible for the antitumor effect of BCG-CWS using the LEEL method in a mouse bladder cancer model
- Nakamura Takashi,Fukiage Masafumi,Suzuki Yoshiteru,Yano Ikuya,Miyazaki Jun,Nishiyama Hiroyuki,Akaza Hideyuki,Harashima Hideyoshi
- Journal of controlled release 196, 161-167, 2014-12-28
- … The CWS-NP allowed us to clarify the machinery associated with the BCG mediated anti-bladder tumor effect, especially the roles of bladder cancer cells and dendritic cells (DCs) in the initial step, which remains poorly understood. … Tumor growth was significantly inhibited in mice that had been inoculated with mouse bladder cancer (MBT-2) cells containing internalized BCG-CWS. …
- NAID 120005537473
- TRC法による大腸癌術中腹腔洗浄液CEA-mRNA測定の意義
- 平野 あづさ,瀬下 明良,亀岡 信悟
- 東京女子医科大学雑誌 84(6), 181-186, 2014-12-25
- 大腸癌術中腹腔洗浄液の微小癌細胞を検出し、その臨床的意義を検討するため、TRC法を用いたCEA-mRNAの測定と、腹腔内洗浄細胞診を行った。対象は初発大腸癌開腹手術症例80例(開腹時測定)とした。同症例中、病変切除再建後の骨盤内洗浄液を、直腸癌14例(直腸再建後測定)で採取した。開腹時測定TRCと臨床病理学的因子を検討し、単変量解析で病変部位(p=0.0035)、浸潤増殖様式(p=0.0230)、 …
- NAID 110009871954
Related Links
- Cancer Growth Animation, Tumor Growth, 3D Medical Animation - What is Cancer?, Cancer: Unregulated Cell Division, Important factors in cancer cell growth, Tumor or Growth on a Dog, Treatment accelerates tumor growth-2
- Cell division is essential for healthy growth of an organism. Cancer happens when cells divide uncontrollably and produce a growing lump or tumor. Originally created for DNA Interactive ( http://www.dnai ...
Related Pictures
★リンクテーブル★
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- 英
- tumor growth、tumor progression
- 関
- 腫瘍成長、腫瘍進行
[★]
- 英
- tumor growth
- 関
- 腫瘍増殖
[★]
- (過去: grew-過去分詞: grown)
- 関
- extend、growth、outgrow、outgrowth、stretch
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