WordNet

act so as to bring into existence; "effect a change"
a symptom caused by an illness or a drug; "the effects of sleep loss"; "the effect of the anesthetic"
(of a law) having legal validity; "the law is still in effect" (同)force
the central meaning or theme of a speech or literary work (同)essence, burden, core, gist
an impression (especially one that is artificial or contrived); "he just did it for effect"
produce; "The scientists set up a shock wave" (同)effectuate, set_up
any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects
property of a personal character that is portable but not used in business; "she left some of her personal effects in the house"; "I watched over their effects until they returned" (同)personal_effects

PrepTutorEJDIC

〈C〉〈U〉『結果』 / 〈C〉〈U〉(…への)『効果』,効きめ,影響《+『on』(『upon』)+『名』》 / 〈C〉(色・音・形などの)印象,感銘 / 《複数形で》品物;身の回り品;動産,財産 / (結果として)…‘を'『もたらす』;〈目的など〉‘を'果たす,遂行する
ステロイド(脂肪溶解性の有機化合物の総称)
禁約な,つましい,控え目な

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1. ステロイドの中断 glucocorticoid withdrawal
2. ステロイドの全身投与の主な副作用 major side effects of systemic glucocorticoids
3. ステロイドの薬理学的使用 pharmacologic use of glucocorticoids
4. ステロイド服用中の外科患者 the surgical patient taking glucocorticoids
5. 早産による新生児の罹病および死亡を減少させるための出産前ステロイド療法 antenatal corticosteroid therapy for reduction of neonatal morbidity and mortality from preterm delivery

Brief Report: A Prospective Open-Label Phase IIa Trial of Tocilizumab in the Treatment of Polymyalgia Rheumatica.

Lally L1, Forbess L2, Hatzis C3, Spiera R3.
Arthritis & rheumatology (Hoboken, N.J.).Arthritis Rheumatol.2016 Oct;68(10):2550-4. doi: 10.1002/art.39740.
OBJECTIVE: Interleukin-6 (IL-6) is a pivotal cytokine in the pathogenesis of polymyalgia rheumatica (PMR), yet the efficacy of IL-6 blockade with tocilizumab (TCZ) for the treatment of PMR is unknown. The aim of this study was to assess the efficacy and safety of TCZ in newly diagnosed PMR.METHODS:
PMID 27159185

Efficacy and safety of rituximab therapy in patients with pemphigus vulgaris: first report from Turkey.

Uzun S1, Bilgiç Temel A2, Akman Karakaş A2, Ergün E2, Özkesici B2, Eskiocak AH2, Erat A2, Uğurlu N2, Nazlım B2, Koç S2, Bozkurt S3, Dicle Ö2, Alpsoy E2, Yılmaz E2.
International journal of dermatology.Int J Dermatol.2016 Sep 22. doi: 10.1111/ijd.13400. [Epub ahead of print]
BACKGROUND: Pemphigus vulgaris (PV) is a severe, chronic, and potentially life-threatening autoimmune blistering disease that affects the skin and mucous membranes. Rituximab is a monoclonal anti-CD20 antibody which has been used increasingly in the therapy of PV.METHODS: The present study sought to
PMID 27653507

Rapid reduction of antibodies and improvement of disease activity by immunoadsorption in Chinese patients with severe systemic lupus erythematosus.

Huang J1,2, Song G3, Yin Z4, He W4, Zhang L5, Kong W4, Ye Z4.
Clinical rheumatology.Clin Rheumatol.2016 Sep;35(9):2211-8. doi: 10.1007/s10067-016-3354-2. Epub 2016 Aug 3.
This was an exploratory analysis comparing the safety and efficacy of immunoadsorption (IAS) combination therapy in severe systemic lupus erythematosus (SLE) receiving corticosteroid pulse and immunosuppressant treatment. Patients enrolled all had predominant organ involvement including proteinuria,
PMID 27488202

Steroid-sparing Effects of Etanercept in a Patient with Steroid-dependent Adult-onset Still's Disease

, , , , ,
Internal Medicine 53(11), 1209-1213, 2014
… We herein report the case of an 84-year-old man with steroid-dependent adult-onset Still's disease (AOSD) whose daily steroid dose was successfully tapered after etanercept treatment. … however, he suffered a relapse due to steroid tapering. … Because treatment with cyclosporine and methotrexate was ineffective, reducing the steroid dose was difficult, and the corticosteroids induced myopathy and diabetes. …
NAID 130004466324

Superiority of Nebulized Corticosteroids over Dry Powder Inhalers in Certain Patients with Cough Variant Asthma or Cough-Predominant Asthma

, , , , , ,
Allergology International 61(3), 411-417, 2012
… In patients receiving high-dose ICS by MDI or DPI (ICS-MDI/DPI), steroid therapy was switched to 1,320μg/day of nebulized dexamethasone (1,600μg as dexamethasone sodium phosphate) (chronic steroid-independent group). …
NAID 130004477143

山口哲生
日本サルコイドーシス／肉芽腫性疾患学会雑誌 32(1), 83-84, 2012
… MTXは，一般に"steroid sparing effect"があるとされ，副腎皮質ステロイドホルモン薬と併用して用いることは海外では多く行われているが単剤での有効性は明らかではない．また，ステロイドとの併用で効果があるといわれても「明らかなevidence 」とは言い難く，それゆえ日本ではあまり用いられておらず，またガイドラインにも掲載されない．これは，サルコイドーシスの多様性（個 …
NAID 130003379770