small G-protein

• 低分子量Gタンパク質、低分子量GTP結合タンパク質

関

monomeric GTP-binding protein、small GTP-binding protein、small GTPase

WordNet

1. slight or limited; especially in degree or intensity or scope; "a series of death struggles with small time in between"
2. a garment size for a small person
3. the slender part of the back
4. limited or below average in number or quantity or magnitude or extent; "a little dining room"; "a little house"; "a small car"; "a little (or small) group" (同)little
5. have fine or very small constituent particles; "a small misty rain"
6. on a small scale; "think small"
7. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
8. a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
9. the 7th letter of the Roman alphabet (同)g

PrepTutorEJDIC

1. (大きさが)『小さい』,小形の;(量が)『少ない』,わずかな / 『取るに足りない』,ささいな(trivial) / 《名詞の前にのみ用いて》(仕事・活動などが)『小規模の』,ささやかな / 心が狭い,利己的な / (音・声が)弱い,小さい / (文字が)小型の,小文字の / 《the~》小さいもの;(…の)細い部分《+『of』+『名』》 / 《複数形で》《英》(衣類・ハンカチなどの)小物,小間物 / 小さく,細かく / (声などが)低く,弱く / 小規模に,こぢんまりと
2. 蛋白(たんばく)質

UpToDate Contents

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• 1. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
• 2. 先天性性腺刺激ホルモン放出ホルモン欠乏症（特発性低ゴナドトロピン性性腺機能低下） congenital gonadotropin releasing hormone deficiency idiopathic hypogonadotropic hypogonadism
• 3. Chapter 6A：ホルモンの作用機序 chapter 6a mechanisms of hormone action
• 4. 正常思春期 normal puberty
• 5. セクレチン secretin

English Journal

• Synergistic antitumor efficacy of sequentially combined paclitaxel with sorafenib in vitro and in vivo NSCLC models harboring KRAS or BRAF mutations.

• Zhang XH, Shin JY, Kim JO, Oh JE, Yoon SA, Jung CK, Kang JH.SourceThe Catholic University of Korea, Seoul, Republic of Korea. xhzn2007@gmail.com
• Cancer letters.Cancer Lett.2012 Sep 28;322(2):213-22. Epub 2012 Mar 17.
• Studies on non-small cell lung cancer (NSCLC) patients with KRAS or BRAF mutations are urgently needed to improve clinical outcomes. We evaluated the cytotoxicities of paclitaxel and sorafenib alone and in combination in NSCLC cell lines with KRAS or BRAF mutations and investigated the mechanism of
• PMID 22433711

• K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.

• Wei F, Liu Y, Bellail AC, Olson JJ, Sun SY, Lu G, Ding L, Yuan C, Wang G, Hao C.SourceDepartment of Hepatobiliary & Pancreas Surgery and Hematology & Oncology, The First Hospital, Jilin University, China.
• Cancer letters.Cancer Lett.2012 Sep 1;322(1):58-69. Epub 2012 Feb 14.
• Mammalian target of rapamycin complex 1 (mTORC1) is frequently activated in human cancers; however, clinical trials of rapalog (the mTORC1 inhibitors) have shown that pancreatic ductal adenocarcinomas (PDACs) resist to the treatment. Rapalog treatment activated the extracellular signal-regulated kin
• PMID 22342683

Japanese Journal

• Opposing Roles of Nitric Oxide and Rho-Kinase in Lipid Metabolism in Mice

• , , , ,
• The Tohoku Journal of Experimental Medicine 235(3), 171-183, 2015
• … Nitric oxide (NO) exerts beneficial effects on lipid metabolism through activation of hepatic sterol regulatory element-binding protein (SREBP)-2, a transcriptional factor for cholesterol metabolism and expression of LDL receptor, while Rho-kinase, an effecter protein of small G protein, RhoA, contributes to the pathogenesis of metabolic syndrome through suppressing the whole body energy consumption. …
• NAID 130004822441

• Role of extracellular proton-sensing OGR1 in regulation of insulin secretion and pancreatic β-cell functions

• , ,
• Endocrine Journal 61(2), 101-110, 2014
• … In addition to ionotropic ion channels, such as transient receptor potential V1 (TRPV1) and acid-sensing ion channels (ASICs), metabotropic proton-sensing G protein-coupled receptors (GPCRs) have also been identified recently as proton-sensing machineries. …
• NAID 130004718264

• 抗がん剤エトポシドの反復経口投与による腸管P-glycoproteinの発現と経口モルヒネの鎮痛効果に及ぼす影響

• 小堀 宅郎,原田 慎一,中本 賀寿夫,徳山 尚吾
• 薬学雑誌. 乙号 134(6), 689-699, 2014
• … RhoA, a small G-protein, and ROCK, an effector of RhoA, pathway has been attracted attention with regard to their involvement in the regulatory mechanism of the expression and activity of P-gp. …
• NAID 130004427992

Related Links

• G protein - Wikipedia, the free encyclopedia

Main article: Small GTPases. Small GTPases also bind GTP and GDP and are involved in signal transduction. ... They are small (20-kDa to 25-kDa) proteins that bind to guanosine triphosphate (GTP). This family ...

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★リンクテーブル★

リンク元	「small GTPase」「small GTP-binding protein」「低分子量GTP結合タンパク質」「monomeric GTP-binding protein」
関連記事	「G」「small」「G protein」「Gd」「g」

「small GTPase」

　　[★]

低分子量GTPase、低分子GTPase、低分子GTPアーゼ、低分子量GTP分解酵素

関

monomeric GTP-binding protein、small G-protein、small guanosine triphosphatase

「small GTP-binding protein」

　　[★]

• 低分子量GTP結合タンパク質、低分子量Gタンパク質

関

small G-protein

「低分子量GTP結合タンパク質」

　　[★]

英

small GTP-binding protein、small G-protein

関

低分子量Gタンパク質

「monomeric GTP-binding protein」

　　[★]

• 単量体GTP結合タンパク質

関

small G-protein、small GTPase

「G」

　　[★]

• グアニン guanine
• グアノシン guanosine
• グリシン glycine

　

「small」

　　[★]

• adj.

• 小さい

関

little、petit、tiny

　 　 　 　 　 　 　

「G protein」

　　[★]

同

G proteins

同

G proteins

「Gd」

　　[★]

同

ガドリニウム造影MRI

「g」

　　[★] グラム

関

gram