WordNet
- undergo a test; "She doesnt test well"
- any standardized procedure for measuring sensitivity or memory or intelligence or aptitude or personality etc; "the test was standardized on a large sample of students" (同)mental test, mental testing, psychometric test
- the act of undergoing testing; "he survived the great test of battle"; "candidates must compete in a trial of skill" (同)trial
- the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial" (同)trial, run
- a hard outer covering as of some amoebas and sea urchins
- put to the test, as for its quality, or give experimental use to; "This approach has been tried with good results"; "Test this recipe" (同)prove, try, try out, examine, essay
- achieve a certain score or rating on a test; "She tested high on the LSAT and was admitted to all the good law schools"
- determine the presence or properties of (a substance)
- show a certain characteristic when tested; "He tested positive for HIV"
- an examination of the characteristics of something; "there are laboratories for commercial testing"; "it involved testing thousands of children for smallpox"
- the act of subjecting to experimental test in order to determine how well something works; "they agreed to end the testing of atomic weapons"
- tested and proved useful or correct; "a tested method" (同)tried, well-tried
- tested and proved to be reliable (同)time-tested, tried, tried and true
- of or relating to serology (同)serological
PrepTutorEJDIC
- (人の能力などの)『試験』,考査,テスト / (物事の)『試験』,検済,試錬,実験《+of+名》 / 化学分析;試薬 / =test match / …‘を'『試験する』,検査する / …‘を'化学分析する / (…の)試験を受ける,試験をする《+for+名》
- testis の複数形
UpToDate Contents
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- 1. サイトメガロウイルス感染の診断検査の概要 overview of diagnostic tests for cytomegalovirus infection
- 2. 国際養子縁組：予防接種に関する懸念事項 international adoption immunization considerations
- 3. Healthcare for adult immigrants and refugees
- 4. 性器潰瘍患者へのアプローチ approach to the patient with genital ulcers
- 5. 性感染症：思春期特有の問題の概要 sexually transmitted diseases overview of issues specific to adolescents
English Journal
- Direct biosensor detection of botulinum neurotoxin endopeptidase activity in sera from patients with type A botulism.
- Lévêque C1, Ferracci G2, Maulet Y3, Mazuet C4, Popoff M4, Seagar M3, El Far O3.Author information 1INSERM, UMR_S 1072, 13015 Marseille, France; Aix-Marseille Université, 13015 Marseille, France. Electronic address: christian.leveque@univ-amu.fr.2CNRS, UMR 7286, Plate-Forme de Recherche en Neurosciences PFRN, 13015 Marseille, France; Aix-Marseille Université, 13015 Marseille, France.3INSERM, UMR_S 1072, 13015 Marseille, France; Aix-Marseille Université, 13015 Marseille, France.4CNR Anaérobies et botulisme, Unité Bactéries anaérobies et toxines. Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France.AbstractBotulinum neurotoxin A (BoNT/A) has intrinsic endoprotease activity specific for SNAP-25, a key protein for presynaptic neurotransmitter release. The inactivation of SNAP-25 by BoNT/A underlies botulism, a rare but potentially fatal disease. There is a crucial need for a rapid and sensitive in vitro serological test for BoNT/A to replace the current in vivo mouse bioassay. Cleavage of SNAP-25 by BoNT/A generates neo-epitopes which can be detected by binding of a monoclonal antibody (mAb10F12) and thus measured by surface plasmon resonance (SPR). We have explored two SPR assay formats, with either mAb10F12 or His6-SNAP-25 coupled to the biosensor chip. When BoNT/A was incubated with SNAP-25 in solution and the reaction products were captured on a mAb-coated chip, a sensitivity of 5fM (0.1LD50/ml serum) was obtained. However, this configuration required prior immunoprecipitation of BoNT/A. A sensitivity of 0.5fM in 10% serum (0.1 LD50/ml serum) was attained when SNAP-25 was coupled directly to the chip, followed by sequential injection of BoNT/A samples and mAb10F12 into the flow system to achieve on-chip cleavage and detection, respectively. This latter format detected BoNT/A endoprotease activity in 50-100µl serum samples from all patients (11/11) with type A botulism within 5h. No false positives occurred in sera from healthy subjects or patients with other neurological diseases. The automated chip-based procedure has excellent specificity and sensitivity, with significant advantages over the mouse bioassay in terms of rapidity, required sample volume and animal ethics.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Jul 15;57:207-12. doi: 10.1016/j.bios.2014.02.015. Epub 2014 Feb 18.
- Botulinum neurotoxin A (BoNT/A) has intrinsic endoprotease activity specific for SNAP-25, a key protein for presynaptic neurotransmitter release. The inactivation of SNAP-25 by BoNT/A underlies botulism, a rare but potentially fatal disease. There is a crucial need for a rapid and sensitive in vitro
- PMID 24583693
- Production of equine herpesvirus 1 recombinant glycoprotein D and development of an agar gel immunodiffusion test for serological diagnosis.
- Fuentealba N1, Sguazza G2, Scrochi M3, Bravi M4, Zanuzzi C5, Corva S6, Gimeno E7, Pecoraro M8, Galosi C9.Author information 1Department of Virology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; National Research Council (CCT-CONICET-La Plata), Argentina. Electronic address: nadiafuentealba@fcv.unlp.edu.ar.2Department of Virology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina. Electronic address: sguazza@fcv.unlp.edu.ar.3Department of Virology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; National Research Council (CCT-CONICET-La Plata), Argentina. Electronic address: scrochimariela@gmail.com.4Department of Virology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; Argentine Agency for the Promotion of Science and Technology (ANPCyT), Argentina. Electronic address: murguita_@hotmail.com.5Department of Histology and Embryology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; Department of Pathology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; National Research Council (CCT-CONICET-La Plata), Argentina. Electronic address: carozanuzzi@gmail.com.6Department of Epidemiology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina. Electronic address: sgcorva@fcv.unlp.edu.ar.7Department of Pathology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; National Research Council (CCT-CONICET-La Plata), Argentina. Electronic address: ejgimeno@gmail.com.8Department of Virology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina. Electronic address: peco@fcv.unlp.edu.ar.9Department of Virology, School of Veterinary Sciences, National University of La Plata, 60 & 118, P.O. Box 296, 1900 La Plata, Buenos Aires, Argentina; Scientific Research Commission of the Province of Buenos Aires (CIC-PBA), Argentina. Electronic address: cmgalosi@fcv.unlp.edu.ar.AbstractEquine herpesvirus 1 and 4 (EHV-1 and 4) infect most of the world's horses, causing serious clinical illness. Viral glycoproteins have been identified as the immunodominant antigens that generate the antiviral serological responses to EHV-1 and EHV-4 in infected horses. Here, glycoprotein D of EHV-1 was expressed by a recombinant baculovirus, purified and evaluated by a simple agar gel immunodiffusion test (AGID). Compared with virus neutralization, serological analysis by AGID showed good specificity (100%) and sensitivity (99.5%). The estimated Kappa values for repeatability and reproducibility were satisfactory. Thus, this rapid, inexpensive, simple and highly specific AGID test seems to be a valuable alternative tool for serological detection of antibodies against both EHV-1 and EHV-4.
- Journal of virological methods.J Virol Methods.2014 Jun 15;202:15-8. doi: 10.1016/j.jviromet.2014.02.025. Epub 2014 Mar 11.
- Equine herpesvirus 1 and 4 (EHV-1 and 4) infect most of the world's horses, causing serious clinical illness. Viral glycoproteins have been identified as the immunodominant antigens that generate the antiviral serological responses to EHV-1 and EHV-4 in infected horses. Here, glycoprotein D of EHV-1
- PMID 24631347
- Strategic use of serology for the diagnosis of bovine tuberculosis after intradermal skin testing.
- Casal C1, Díez-Guerrier A2, Alvarez J3, Rodriguez-Campos S4, Mateos A2, Linscott R5, Martel E5, Lawrence JC5, Whelan C6, Clarke J6, O'Brien A6, Domínguez L4, Aranaz A7.Author information 1Centro VISAVET, Universidad Complutense de Madrid, Av. Puerta de Hierro s/n, 28040 Madrid, Spain.2Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Av. Puerta de Hierro s/n, 28040 Madrid, Spain.3Centro VISAVET, Universidad Complutense de Madrid, Av. Puerta de Hierro s/n, 28040 Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ctra. Colmenar Viejo, Km. 9100, 28034 Madrid, Spain.4Centro VISAVET, Universidad Complutense de Madrid, Av. Puerta de Hierro s/n, 28040 Madrid, Spain; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Av. Puerta de Hierro s/n, 28040 Madrid, Spain.5IDEXX Livestock and Poultry Diagnostics, 1 Idexx Dr., Westbrook, ME 04092, USA.6Enfer Scientific, Unit T, M7 Business Park, Newhall, Naas, Kildare, Ireland.7Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Av. Puerta de Hierro s/n, 28040 Madrid, Spain. Electronic address: alaranaz@ucm.es.AbstractDiagnostic tests based on cell-mediated immunity are used in programmes for eradication of bovine tuberculosis (Mycobacterium bovis). Serological assays could be applied as ancillary methods to detect infected animals. Our objective was to evaluate two serological techniques: M. bovis Ab Test (IDEXX, USA) and Enferplex™ TB assay (Enfer, Ireland) in animals tested simultaneously with the single and comparative intradermal tests and the interferon-gamma assay. This work was performed at two stages. First, a preliminary panel of samples collected prior to intradermal tests from tuberculosis-free (n=60) and M. bovis-infected herds (n=78) was assayed, obtaining high specificity: 100% (M. bovis Ab Test) and 98.3% (Enferplex TB assay) but low sensitivity (detection of M. bovis infected animals): 23.9% (M. bovis Ab Test) and 32.6% (Enferplex TB assay). Subsequently, the use of serological techniques was further studied in two herds with M. bovis infection (n=77) using samples collected prior to, and 72h and 15 days after PPD inoculation. The highest level of detection of infected animals for serology was achieved at 15 days post-intradermal tests taking advantage of the anamnestic effect: 70.4% and 85.2% in herd A, and 66.7% and 83.3% in herd B, using M. bovis Ab Test and Enferplex TB assay, respectively. Quantitative results (average values obtained with M. bovis Ab Test ELISA and degree of positivity obtained with Enferplex TB assay) were higher in animals showing lesions compatible with tuberculosis. No significant differences were observed in the number of confirmed infected animals detected with either serological technique.
- Veterinary microbiology.Vet Microbiol.2014 Jun 4;170(3-4):342-51. doi: 10.1016/j.vetmic.2014.02.036. Epub 2014 Mar 2.
- Diagnostic tests based on cell-mediated immunity are used in programmes for eradication of bovine tuberculosis (Mycobacterium bovis). Serological assays could be applied as ancillary methods to detect infected animals. Our objective was to evaluate two serological techniques: M. bovis Ab Test (IDEXX
- PMID 24679958
Japanese Journal
- Neurosyphilis Is a Long-forgotten Disease but Still a Possible Etiology for Dementia
- Internal Medicine 54(21), 2769-2773, 2015
- NAID 130005106612
- 慢性肝炎における肝線維化マーカーELFスコアの有用性
- 肝臓 56(10), 543-545, 2015
- NAID 130005106527
- Comparison of Direct Culture, Immunomagnetic Separation/culture, and Multiplex PCR Methods for Detection of Salmonella in Food
- Food Science and Technology Research 21(5), 671-675, 2015
- NAID 130005106153
Related Links
- MLA style: "serological test". Encyclopædia Britannica. Encyclopædia Britannica Online. Encyclopædia Britannica Inc., 2015. Web. 07 Dec. 2015 < http://www.britannica.com/topic/serological-test >. APA style: serological test.
- serologic test [sēr″o-loj´ik] any laboratory test involving serologic reactions, such as precipitin reaction, agglutination, or complement fixation, especially any such test measuring serum antibody titer. serologic test for syphilis (STS ...
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★リンクテーブル★
| リンク元 | 「serologic test」「serodiagnosis」「免疫血清検査」「血清学的試験」 |
| 関連記事 | 「testing」「serologic」「serological」「test」 |
「serologic test」
「serodiagnosis」
「免疫血清検査」
「血清学的試験」
- 英
- serological test
- 関
- 血清診断、血清試験
「testing」
- n.
- 関
- assessment、data quality、exam、examination、examine、experimental design、matched group、measurement、research design、scoring method、test、trial
「serologic」
- 血清学的な、血清学の
「serological」
- 血清学的な、血清学の