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the branch of medical science that deals with serums; especially with blood serums and disease
of or relating to serology (同)serological

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/07 10:53:41」(JST)

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Serology is the scientific study of serum and other bodily fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum.^[1] Such antibodies are typically formed in response to an infection (against a given microorganism),^[2] against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease).

Serological tests may be performed for diagnostic purposes when an infection is suspected, in rheumatic illnesses, and in many other situations, such as checking an individual's blood type.^[1] Serology blood tests help to diagnose patients with certain immune deficiencies associated with the lack of antibodies, such as X-linked agammaglobulinemia. In such cases, tests for antibodies will be consistently negative.

There are several serology techniques that can be used depending on the antibodies being studied. These include: ELISA, agglutination, precipitation, complement-fixation, and fluorescent antibodies.

Some serological tests are not limited to blood serum, but can also be performed on other bodily fluids such as semen and saliva, which have (roughly) similar properties to serum.

Serological tests may also be used in forensic serology, specifically for a piece of evidence (e.g., linking a rapist to a semen sample).

Serological surveys

Serological surveys are often used by epidemiologists to determine the prevalence of a disease in a population. Such surveys are sometimes performed by random, anonymous sampling from samples taken for other medical tests.

Notes and references

^ ^a ^b Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 247–9. ISBN 0-8385-8529-9.
^ Washington JA (1996). Principles of Diagnosis: Serodiagnosis. in: Baron's Medical Microbiology (Baron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. ISBN 0-9631172-1-1.

External links

Serology (archived) – MedlinePlus Medical Encyclopedia
Serologic Tests at the US National Library of Medicine Medical Subject Headings (MeSH)

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English Journal

Immunological challenges for peptide-based immunotherapy in glioblastoma.

Mohme M, Neidert MC, Regli L, Weller M, Martin R.SourceDepartment of Neurosurgery, University Hospital Zurich, 8091 Zurich, Switzerland; Center for Molecular Neurobiology Hamburg, University Medical Center Eppendorf, 20251 Hamburg, Germany. Electronic address: malte.mohme@zmnh.uni-hamburg.de.
Cancer treatment reviews.Cancer Treat Rev.2014 Mar;40(2):248-58. doi: 10.1016/j.ctrv.2013.08.008. Epub 2013 Sep 8.
Glioblastoma is the most aggressive primary tumor of the central nervous system with a medium overall survival of 7-15months after diagnosis. Since tumor cells penetrate the surrounding brain tissue, complete surgical resection is impossible and tumor recurrence is almost a certainty. New treatment
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Advanced Motion Compensation Methods for Intravital Optical Microscopy.

Vinegoni C, Lee S, Feruglio PF, Weissleder R.SourceCenter for System Biology, Massachusetts General Hospital and Harvard Medical School, Richard B. Simches Research Center, 185 Cambridge Street, Boston 02114, USA.
IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society.IEEE J Sel Top Quantum Electron.2014 Mar;20(2). doi: 10.1109/JSTQE.2013.2279314.
Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for the study of the micro-dynamics of biological processes in live animals. Technical advancements in imaging techniques and hardware components, combined with the development of novel targeted probes and ne
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IgA deficiency and autoimmunity.

Singh K, Chang C, Gershwin ME.Source451 E. Health Sciences Drive, Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616, United States.
Autoimmunity reviews.Autoimmun Rev.2014 Feb;13(2):163-77. doi: 10.1016/j.autrev.2013.10.005. Epub 2013 Oct 21.
IgA is the most abundant immunoglobulin in the human body, and performs a very specialized role which involves mucosal immunity, development of tolerance and protection against infection. IgA is the key immunoglobulin in the respiratory and gastrointestinal tracts, which provide the most intimate in
PMID 24157629

Japanese Journal

Seroprevalence of Toxoplasma gondii in Donkeys (Equus asinus) in Italy

MACHACOVA Tereza,BARTOVA Eva,DI LORIA Antonio [他]
The journal of veterinary medical science 76(2), 265-267, 2014-02
NAID 40019993389

Microbiological survey of mice (Mus musculus) purchased from commercial pet shops in Kanagawa and Tokyo, Japan

HAYASHIMOTO Nobuhito,MORITA Hanako,ISHIDA Tomoko,UCHIDA Ritsuki,TANAKA Mai,OZAWA Midori,YASUDA Masahiko,ITOH Toshio
Experimental Animals, 2014
… The survey was conducted in 28 mice from 5 pet shops to screen for 47 items (17 viruses, 22 bacteria and fungi, 10 parasites) using culture tests, serology, PCR, and microscopy. …
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A Case Series of Possibly Recrudescent Orientia tsutsugamushi Infection Presenting as Pneumonia

Im Jae-Hyoung,Baek Ji Hyeon,Lee Jin-Soo,Chung Moon-Hyun,Lee Sun Myoung,Kang Jae-Seung
Japanese Journal of Infectious Diseases 67(2), 122-126, 2014
… tsutsugamushi infection by serology, nested polymerase chain reaction (PCR), and cell culture. …
NAID 130003399246