- Positive quellung reaction: if encapsulated bug is present, capsule swells when specific anticapsular antisera are added.
WordNet
- (mechanics) the equal and opposite force that is produced when any force is applied to a body; "every action has an equal and opposite reaction"
- a response that reveals a persons feelings or attitude; "he was pleased by the audiences reaction to his performance"; "John feared his mothers reaction when she saw the broken lamp"
- a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age" (同)response
- doing something in opposition to another way of doing it that you dont like; "his style of painting was a reaction against cubism"
- an idea evoked by some experience; "his reaction to the news was to start planning what to do"
- extreme conservatism in political or social matters; "the forces of reaction carried the election"
- the swelling of the capsule surrounding a microorganism after reaction with an antibody; the basis of certain tests for identifying microorganisms; "pneumococcus quellung" (同)quellung_reaction
PrepTutorEJDIC
- {名}(…に対する)『反応』《+『to』+『名』》 / 〈U〉(…に対する)(政治的・社会的な)『反動』,逆コース《+『against』+『名』》 / 〈U〉〈C〉化学反応,化学変化 / 〈U〉〈C〉(物理学で)反作用
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/19 16:10:40」(JST)
[Wiki en表示]
The Quellung reaction is a biochemical reaction in which antibodies bind to the bacterial capsule of Streptococcus pneumoniae, Klebsiella pneumoniae, Neisseria meningitidis, Haemophilus influenzae,[1] Escherichia coli, and Salmonella. The antibody reaction allows these species to be visualized under a microscope. If the reaction is positive, the capsule becomes opaque and appears to enlarge.
Quellung is the German word for "swelling" and describes the microscopic appearance of pneumococcal or other bacterial capsules after their polysaccharide antigen has combined with a specific antibody. The antibody usually comes from a bit of serum taken from an immunized laboratory animal. As a result of this combination, and precipitation of the large, complex molecule formed, the capsule appears to swell, because of increased surface tension, and its outlines become clearly demarcated.
The pneumococcal Quellung reaction was first described in 1902 [2] by the scientist Fred Neufeld, both as microscopic capsular swelling and macroscopic agglutination (clumping visible with the naked eye). It has been used to identify the 93 known capsular serotypes of Streptococcus pneumoniae in a diagnostic setting, but in recent years has been challenged by molecular typing techniques which target genetic differences.[3]
References
- ^ Fisher, Bruce; Harvey, Richard P.; Champe, Pamela C. Lippincott's Illustrated Reviews: Microbiology (Lippincott's Illustrated Reviews Series). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-8215-5. Page 340
- ^ Neufeld, F (1902). "Ueber die Agglutination der Pneumokokken und uber die Theorien der Agglutination.". Zeitschrift fur Hygiene Infektionskrankheiten. pp. 54–72.
- ^ PCR Deduction of Pneumococcal Serotypes. Center for Disease Control. Retrieved October 22, 2010.
Further reading
- Park, I. H., Pritchard, D., Cartee, R., Brandao, A., Brandileone, M. & Nahm, M. (2007). Discovery of a new capsular serotype (6C) within serogroup 6 of Streptococcus pneumoniae. J Clin Microbiol 45, 1225–1233.
- Pai R, R. E. Gertz, B. Beall. 2006. Sequential multiplex PCR approach for determining capsular serotypes of Streptococcus pneumoniae isolates. J. Clin. Microbiol. 44:124-31.
UpToDate Contents
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English Journal
- Evolution and molecular characterization of macrolide-resistant Streptococcus pneumoniae in Canada between 1998 and 2008.
- Wierzbowski AK, Karlowsky JA, Adam HJ, Nichol KA, Hoban DJ, Zhanel GG; Canadian Antimicrobial Resistance Alliance (CARA).Author information Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba R3E 0J9, Canada.AbstractOBJECTIVES: Studies were performed to assess resistance mechanisms, multidrug resistance (MDR), genetic relatedness, serotype distribution, heptavalent pneumococcal conjugate vaccine (PCV7) coverage and pili virulence factors among macrolide-resistant Streptococcus pneumoniae (MRSP) isolated from respiratory samples submitted to hospital laboratories across Canada from 1998 to 2008.
- The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2014 Jan;69(1):59-66. doi: 10.1093/jac/dkt332. Epub 2013 Aug 22.
- OBJECTIVES: Studies were performed to assess resistance mechanisms, multidrug resistance (MDR), genetic relatedness, serotype distribution, heptavalent pneumococcal conjugate vaccine (PCV7) coverage and pili virulence factors among macrolide-resistant Streptococcus pneumoniae (MRSP) isolated from re
- PMID 23970485
- Susceptibility profiles and correlation with pneumococcal serotypes soon after implementation of the 10-valent pneumococcal conjugate vaccine in Brazil.
- Mott M1, Caierão J2, Rosa da Cunha G1, Rodrigues Perez LR3, Matusiak R4, Pilger de Oliveira KR5, d'Azevedo PA1, Dias C6.Author information 1Universidade Federal de Ciências da Saúde de Porto Alegre, Sarmento Leite, 245, Porto Alegre, Rio Grande do Sul, Brazil.2Universidade Federal de Ciências da Saúde de Porto Alegre, Sarmento Leite, 245, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address: julianaca@ufcspa.edu.br.3Hospital Mãe de Deus, Porto Alegre, Rio Grande do Sul, Brazil.4Grupo Hospitalar Conceição, Porto Alegre, Rio Grande do Sul, Brazil.5Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.6Universidade Federal de Ciências da Saúde de Porto Alegre, Sarmento Leite, 245, Porto Alegre, Rio Grande do Sul, Brazil; Hospital Mãe de Deus, Porto Alegre, Rio Grande do Sul, Brazil.AbstractOBJECTIVES: To evaluate the susceptibility patterns among Streptococcus pneumoniae recovered during the years 2010-2012 and to correlate these with serotypes.
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.Int J Infect Dis.2013 Dec 31. pii: S1201-9712(13)00372-X. doi: 10.1016/j.ijid.2013.11.009. [Epub ahead of print]
- OBJECTIVES: To evaluate the susceptibility patterns among Streptococcus pneumoniae recovered during the years 2010-2012 and to correlate these with serotypes.METHODS: Pneumococci from invasive sites were serotyped by sequential multiplex PCR and/or Quellung reaction. Etest strips were used to determ
- PMID 24389158
- Recurrent pneumococcal invasive disease in the Region of Madrid during a five-year period.
- Sanz JC, Rodríguez-Avial I, Ríos E, Ramos B, Cercenado E.Author information Unidad de Microbiología Clínica, Laboratorio Regional de Salud Pública, Comunidad de Madrid, C/Sierra de Alquife 8, 28053, Madrid, Spain, juan.sanz@salud.madrid.org.AbstractPURPOSE: The aim of this study was to describe the clinical and microbiological characteristics of recurrent invasive pneumococcal disease (RIPD) cases identified in the Region of Madrid between January 2007 and December 2011.
- Infection.Infection.2013 Dec 22. [Epub ahead of print]
- PURPOSE: The aim of this study was to describe the clinical and microbiological characteristics of recurrent invasive pneumococcal disease (RIPD) cases identified in the Region of Madrid between January 2007 and December 2011.METHODS: Streptococcus pneumoniae serotyping was performed by Pneumotest-L
- PMID 24363222
Related Links
- The Quellung reaction is a biochemical reaction in which antibodies bind to the bacterial capsule of Streptococcus pneumoniae, Klebsiella pneumoniae, Neisseria meningitidis, Haemophilus influenzae, Salmonella, and group B Strep ...
★リンクテーブル★
[★]
- 英
- capsule
- 関
機能
- 抗体を介した貪食による (SMB.43)
- 抗体の産生には1週間ていどかかるらしい
- 補体は無効
- 補体が莢膜に接着しない
- 膜攻撃複合体が細胞膜に達しない
莢膜を有する病原体
莢膜を有する病原体(First Aid 2006 p.137)
- SHNK
検査
- if encapsulated bug is present, capsule swells when specific anticapsular antisera are added.
[★]
- 関
- react、respond、response、responsive