pyrimidine dimer DNA glycosylase

ピリミジン二量体DNAグリコシラーゼ

WordNet

1. lacking in light; not bright or harsh; "a dim light beside the bed"; "subdued lights and soft music" (同)subdued
2. become dim or lusterless; "the lights dimmed and the curtain rose"
3. make dim or lusterless; "Time had dimmed the silver"
4. switch (a cars headlights) from a higher to a lower beam (同)dip
5. lacking clarity or distinctness; "a dim figure in the distance"; "only a faint recollection"; "shadowy figures in the gloom"; "saw a vague outline of a building through the fog"; "a few wispy memories of childhood" (同)faint, shadowy, vague, wispy
6. the 4th letter of the Roman alphabet (同)d
7. a heterocyclic organic compound with a penetrating odor
8. any of several basic compounds derived from pyrimidine
9. a United States coin worth one tenth of a dollar

PrepTutorEJDIC

1. 『薄暗い』,ほの暗い / はっきり見えない(聞こえない,理解できない) / (考え・記憶などが)はっきりしない,ぼんやりした / (色などが)くすんだ,光沢のない / 批判的な,悲観的な / 《話》(人が)ばかな,愚かな / (目が)かすんだ / …‘を'『薄暗くする』,ぼんやりさせる / 『薄暗くなる』,かすかになる
2. deuteriumの化学記号
3. ダイム(米国およびカナダの10セント銀貨)
4. deoxyribonucleic acidディオキシリボ核酸

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/18 23:23:03」(JST)

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Deoxyribodipyrimidine endonucleosidase
Identifiers
EC number	3.2.2.17
CAS number	75302-33-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Deoxyribodipyrimidine endonucleosidase (EC 3.2.2.17, pyrimidine dimer DNA-glycosylase, endonuclease V, deoxyribonucleate pyrimidine dimer glycosidase, pyrimidine dimer DNA glycosylase, T4-induced UV endonuclease, PD-DNA glycosylase) is an enzyme with system name deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase. This enzyme catalyses the following chemical reaction

Cleaves the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue

References

External links

• Deoxyribodipyrimidine endonucleosidase at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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English Journal

• Visualization of UV-induced damage on single DNA molecules.

• Lee J1, Park HS, Lim S, Jo K.
• Chemical communications (Cambridge, England).Chem Commun (Camb).2013 May 25;49(42):4740-2. doi: 10.1039/c3cc38884k.
• Ultraviolet radiation induced DNA damage such as double stranded breaks and single stranded breaks is visualized at the level of single DNA molecules. Molecular observations provide a map of DNA radiation-mediated breakages, revealing the sequence dependency of DNA damage rather than random occurren
• PMID 23369943

• Carbinolamine formation and dehydration in a DNA repair enzyme active site.

• Dodson ML1, Walker RC, Lloyd RS.
• PloS one.PLoS One.2012;7(2):e31377. doi: 10.1371/journal.pone.0031377. Epub 2012 Feb 22.
• In order to suggest detailed mechanistic hypotheses for the formation and dehydration of a key carbinolamine intermediate in the T4 pyrimidine dimer glycosylase (T4PDG) reaction, we have investigated these reactions using steered molecular dynamics with a coupled quantum mechanics-molecular mechanic
• PMID 22384015

• Modulation of the processive abasic site lyase activity of a pyrimidine dimer glycosylase.

• Ryabinina OP1, Minko IG, Lasarev MR, McCullough AK, Lloyd RS.
• DNA repair.DNA Repair (Amst).2011 Oct 10;10(10):1014-22. doi: 10.1016/j.dnarep.2011.07.015. Epub 2011 Sep 1.
• The repair of cis-syn cyclobutane pyrimidine dimers (CPDs) can be initiated via the base excision repair (BER) pathway, utilizing pyrimidine dimer-specific DNA glycosylase/lyase enzymes (pdgs). However, prior to incision at lesion sites, these enzymes bind to non-damaged DNAs through charge-charge i
• PMID 21889915

Japanese Journal

• A pyrimidine dimer-DNA glycosylase activity associated with the v gene product of bacteriophase T4

• Nature 286, 182-185, 1984
• NAID 30013927796

• Physical association of pyrimidine dimer DNA glycosylase and apruinic/apyrimidinic DNA endonuclease essential for repair for repair of ultraviolet-damaged DNA.

• Proc. Natl. Acad. Sci. USA 78, 2742-2746, 1981
• NAID 80000904833

• Cleavage of pyrimidine dimers in specific DNA sequences by a pyrimidine dimer DNA-glycosylase of M. luteus

• Nature 285, 634-641, 1980
• NAID 30013927350

Related Links

• Pyrimidine dimer DNA-glycosylase | Online references ...

References for "Pyrimidine dimer DNA-glycosylase" im Internet, an Universitäten und in der Literatur... cyclopaedia.net ... An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important ...

• Pyrimidine dimer DNA glycosylase | Online references ...

References for "Pyrimidine dimer DNA glycosylase" im Internet, an Universitäten und in der Literatur... cyclopaedia.net ... An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important ...

Related Pictures

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★リンクテーブル★

リンク元	「UVエンドヌクレアーゼ」「ピリミジン二量体DNAグリコシラーゼ」
関連記事	「D」「dim」「DNA」

「UVエンドヌクレアーゼ」

　　[★]

英

UV-endonuclease

同

紫外線エンドヌクレアーゼ、UV-DNAグリコシラーゼ UV-DNA glycosylase、ピリミジン二量体DNAグリコシラーゼ pyrimidine dimer DNA glycosylase

「ピリミジン二量体DNAグリコシラーゼ」

　　[★]

英

pyrimidine dimer DNA glycosylase

関

UVエンドヌクレアーゼ、ピリミジン

「D」

　　[★]

• アスパラギン酸
• ジヒドロウリジン
• 遠位の distal,
• うつ病 depression
• 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)

　 　

「dim」

　　[★]

• adj.

• 薄暗い、(音が)かすかな

関

faint、faintly、subtle、subtly

　 　 　 　 　 　

「DNA」

　　[★]

英

deoxyribonucleic acid

同

デオキシリボ核酸

関

リボ核酸 RNA