多形日光疹 polymorphous light eruption

WordNet

very thin and insubstantial; "thin paper"; "light summer dresses"
make lighter or brighter; "This lamp lightens the room a bit" (同)illume, illumine, light_up, illuminate
a condition of spiritual awareness; divine illumination; "follow Gods light" (同)illumination
having abundant light or illumination; "they played as long as it was light"; "as long as the lighting was good" (同)lighting
(physics) electromagnetic radiation that can produce a visual sensation; "the light was filtered through a soft glass window" (同)visible_light, visible_radiation
any device serving as a source of illumination; "he stopped the car and turned off the lights" (同)light_source
the visual effect of illumination on objects or scenes as created in pictures; "he could paint the lightest light and the darkest dark" (同)lightness
a particular perspective or aspect of a situation; "although he saw it in a different light, he still did not understand"
a person regarded very fondly; "the light of my life"
a visual warning signal; "they saw the light of the beacon"; "there was a light at every corner"
an illuminated area; "he stepped into the light"
mental understanding as an enlightening experience; "he finally saw the light"; "can you shed light on this problem?"
public awareness; "it brought the scandal to light"
(used of color) having a relatively small amount of coloring agent; "light blue"; "light colors such as pastels"; "a light-colored powder" (同)light-colored
moving easily and quickly; nimble; "the dancer was light and graceful"; "a lightsome buoyant step"; "walked with a light tripping step" (同)lightsome, tripping
having relatively few calories; "diet cola"; "light (or lite) beer"; "lite (or light) mayonnaise"; "a low-cal diet" (同)lite, low-cal, calorie-free
less than the correct or legal or full amount often deliberately so; "a light pound"; "a scant cup of sugar"; "regularly gives short weight" (同)scant, short
(of sleep) easily disturbed; "in a light doze"; "a light sleeper"; "a restless wakeful night" (同)wakeful
(physics, chemistry) not having atomic weight greater than average; "light water is ordinary water"
(used of soil) loose and large-grained in consistency; "light soil"
characterized by or emitting light; "a room that is light when the shutters are open"; "the inside of the house was airy and light"
demanding little effort; not burdensome; "light housework"; "light exercise"
designed for ease of movement or to carry little weight; "light aircraft"; "a light truck"
easily assimilated in the alimentary canal; not rich or heavily seasoned; "a light diet"
having little importance; "losing his job was no light matter"
intended primarily as entertainment; not serious or profound; "light verse"; "a light comedy"
not great in degree or quantity or number; "a light sentence"; "a light accent"; "casualties were light"; "light snow was falling"; "light misty rain"; "light smoke from the chimney"
of comparatively little physical weight or density; "a light load"; "magnesium is a light metal--having a specific gravity of 1.74 at 20 degrees C"
of little intensity or power or force; "the light touch of her fingers"; "a light breeze"
of the military or industry; using (or being) relatively small or light arms or equipment; "light infantry"; "light cavalry"; "light industry"; "light weapons"
psychologically light; especially free from sadness or troubles; "a light heart"
(of volcanos) pouring out fumes or lava (or a deposit so formed) (同)eructation, extravasation
symptom consisting of a breaking out and becoming visible
the emergence of a tooth as it breaks through the gum
relating to the occurrence of more than one kind of individual (independent of sexual differences) in an interbreeding population; "a polymorphic species" (同)polymorphous
having or occurring in several distinct forms; "man is both polymorphic and polytypic"; "a polymorphous god" (同)polymorphous
apparatus for supplying artificial light effects for the stage or a film
the craft of providing artificial light; "an interior decorator must understand lighting"
an organism that can assume more than one adult form as in the castes of ants or termites

PrepTutorEJDIC

〈U〉『光,光線』;明るさ / 〈U〉夜明け;日中;日光 / 〈C〉『明かり』(太陽・灯火など光を出すもの) / 〈U〉《時にa~》光輝(brightness),(目などの)輝き / 〈C〉(点火するための)火,火花 / 〈C〉明かり採り,採光窓 / 〈C〉《通例単数形で》(絵などの)明るい部分 / 〈U〉(…についての)知識,情報,理解《+『on』+『名』》 / 〈C〉(ものを見る)観点,見地;相 / 〈C〉この世に光を与える人;指導的な人物 / …‘に'『火をつける』《+『up』+『名』+『名』+『up』》 / …‘に'『明かりをつける』,‘を'照らす《+『up』+『名,』+『名』+『up』》 / 〈人〉‘を'明かりをつけて案内する / 〈表情など〉‘を'明るくする《+『up』+『名,』+『名』+『up』》 / 〈物が〉火がつく,点火する;明かりがつく《+『up』》 / 明るくなる,晴れ晴れする《+『up』》 / 『明るい』 / (色が)『薄い』
(重量が)『軽い』 / (いろいろな事について,その程座・量が)軽い,小さい / 『軽快な』 / 軽装の / 肩のこらない;気軽な / 手軽な,骨の折れなし / (食べ物が)消化のよい,もたれない / ふらふらする,目まいのする / アルコール分の少ない / (パンなどが)ふんわりした / (重量が)軽く / (程度が)軽く,容易に;軽装で
(車・馬などから)降りる《+『from』+『名』》(alight) / (木などに)〈鳥などが〉止まる《+『on』(『upon』)+『名』》 / (…に)〈打撃・運などが〉突然ふりかかる《+『on』(『upon』)+『名』》
(病気・災害などの)『突発』,(戦争などの)勃(ぼっ)発;(怒り・笑いの)爆発《+『of』+『名』》 / (溶岩・熱湯などの)『噴出』;(火山の)『噴出』;(火山の)『噴火』《+『of』+『名』》;(火山・間欠泉などからの)噴出物
照明,点火 / 照明方法(装置)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/03/05 12:08:56」(JST)

wiki en

Polymorphous light eruption (PLE), or polymorphic light eruption (PMLE), is a skin condition caused by sunlight.

Types

Two subtypes have been described:^[1]

Juvenile spring eruption
Benign summer light eruption

Presentation

Symptoms include skin irritations, which may be itchy or painful, and are sometimes confused with hives. These irritations appear upon exposure to sunlight—sometimes only hours after exposure^[2]—and may last from 1 to 7 days.

Epidemiology

The cases of this condition are most common between the spring and autumn months in the northern hemisphere.

Typically, 5-20% of fair skinned populations are affected, but it can occur in any skin type.^[3] It is more common in females than in males. The condition can affect all ethnic groups and research suggests that 20% of patients have a family history of the complaint.^{[citation needed]} Those suffering from PLE usually do so by age 30.

Causes and prevention

It has been noted that PMLE is caused by an immune reaction to a compound in the skin which is altered by exposure to ultraviolet light. It can be provoked by UVA or UVB rays.

The cause of PLE is not yet understood. It is thought to be due to a type IV delayed-type hypersensitivity to an allergen produced in the body following sunlight exposure.^[3]

One may also purchase clothing that has been tested for its protective qualities.

Some progression to autoimmune disease has been observed.^[4]

Prognosis

Generally, PLE resolves without treatment; also, PLE irritations generally leave no scar.

References

^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
^ Schornagel IJ, Sigurdsson V, Nijhuis EH, Bruijnzeel-Koomen CA, Knol EF (July 2004). "Decreased neutrophil skin infiltration after UVB exposure in patients with polymorphous light eruption". J. Invest. Dermatol. 123 (1): 202–6. doi:10.1111/j.0022-202X.2004.22734.x. PMID 15191561.
^ ^a ^b http://www.clinuvel.com/skin-conditions/common-skin-conditions/polymorphous-light-eruption-ple
^ Hasan T, Ranki A, Jansen CT, Karvonen J (September 1998). "Disease associations in polymorphous light eruption. A long-term follow-up study of 94 patients". Arch Dermatol 134 (9): 1081–5. doi:10.1001/archderm.134.9.1081. PMID 9762018. http://archderm.ama-assn.org/cgi/pmidlookup?view=long&pmid=9762018.

External links

DermAtlas -820033183
www.mayoclinic.com
www.emedicine.com
www.netdoctor.co.uk
www.dermadoctor.com
dermnetnz.org

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UpToDate Contents

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1. 多形日光疹 polymorphous light eruption
2. 光線過敏症（光線皮膚症）：臨床症状、診断、および治療 photosensitivity disorders photodermatoses clinical manifestations diagnosis and treatment
3. 日焼け sunburn
4. 斑状の皮膚病変を有する患者へのアプローチ approach to the patient with macular skin lesions
5. 皮膚光線過敏症の概要：光生物学、患者評価、および光保護 overview of cutaneous photosensitivity photobiology patient evaluation and photoprotection

English Journal

T regulatory cells and related immunoregulatory factors in polymorphic light eruption following ultraviolet A1 challenge.

Gambichler T1, Terras S, Kampilafkos P, Kreuter A, Skrygan M.Author information 1Department of Dermatology, Ruhr-University Bochum, Gudrunstraße 56, 44791, Bochum, Germany.AbstractBACKGROUND: Polymorphic light eruption (PLE) is considered to be an autoimmune-mediated skin condition in which the normal ultraviolet (UV)-induced local immunosuppression appears to be absent, leading to recognition of photoinduced autoantigens and subsequent inflammation.
The British journal of dermatology.Br J Dermatol.2013 Dec;169(6):1288-94. doi: 10.1111/bjd.12608.
BACKGROUND: Polymorphic light eruption (PLE) is considered to be an autoimmune-mediated skin condition in which the normal ultraviolet (UV)-induced local immunosuppression appears to be absent, leading to recognition of photoinduced autoantigens and subsequent inflammation.OBJECTIVES: To investigate
PMID 24032533

A clinical study of the spectrum of photodermatoses in dark-skinned populations.

Wadhwani AR1, Sharma VK, Ramam M, Khaitan BK.Author information 1Department of Dermatology and Venereology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.AbstractBACKGROUND: Photodermatoses are characterized by an abnormal cutaneous response to 'ordinary' light exposure.
Clinical and experimental dermatology.Clin Exp Dermatol.2013 Dec;38(8):823-9. doi: 10.1111/ced.12098. Epub 2013 Jun 13.
BACKGROUND: Photodermatoses are characterized by an abnormal cutaneous response to 'ordinary' light exposure.AIM: To study the spectrum of photodermatoses in populations with dark skin (skin types IV-VI) at a tertiary referral centre.METHODS: Consecutive patients with skin lesions confined to or pre
PMID 23758593

Prevention of polymorphic light eruption by oral administration of a nutritional supplement containing lycopene, β-carotene, and Lactobacillus johnsonii: results from a randomized, placebo-controlled, double-blinded study.

Marini A1, Jaenicke T, Grether-Beck S, Le Floc'h C, Cheniti A, Piccardi N, Krutmann J.Author information 1IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.AbstractBACKGROUND: Polymorphic light eruption (PLE) is the most common photodermatosis. Little is known about the efficacy of systemic photoprotection provided by nutritional supplements in PLE patients.
Photodermatology, photoimmunology & photomedicine.Photodermatol Photoimmunol Photomed.2013 Nov 28. doi: 10.1111/phpp.12093. [Epub ahead of print]
BACKGROUND: Polymorphic light eruption (PLE) is the most common photodermatosis. Little is known about the efficacy of systemic photoprotection provided by nutritional supplements in PLE patients.PURPOSE: The purpose of this study was to assess efficacy of nutritional supplement containing lycopene,
PMID 24283388