WordNet

the amount by which the cost of a business exceeds its revenue; "the company operated at a loss last year"; "the company operated in the red last year" (同)red ink, red
gradual decline in amount or activity; "weight loss"; "a serious loss of business"
something that is lost; "the car was a total loss"; "loss of livestock left the rancher bankrupt"
the disadvantage that results from losing something; "his loss of credibility led to his resignation"; "losing him is no great deprivation" (同)deprivation
the act of losing someone or something; "everyone expected him to win so his loss was a shock"
the experience of losing a loved one; "he sympathized on the loss of their grandfather"
remove the bones from; "bone the turkey before roasting it" (同)debone
the porous calcified substance from which bones are made (同)osseous_tissue
consisting of or made up of bone; "a bony substance"; "the bony framework of the body"
a shade of white the color of bleached bones (同)ivory, pearl, off-white
rigid connective tissue that makes up the skeleton of vertebrates (同)os
having bones as specified; "his lanky long-boned body"
having had the bones removed; "a boneless rib roast"; "a boned (or deboned) fish" (同)deboned
a percussion instrument consisting of a pair of hollow pieces of wood or bone (usually held between the thumb and fingers) that are made to click together (as by Spanish dancers) in rhythm with the dance (同)castanets, clappers, finger cymbals
cell that functions in the breakdown and resorption of bone tissue

PrepTutorEJDIC

〈U〉(…を)『失うこと』,紛失《+『of』+『名』》 / 〈C〉(…の)『損害』,損失;損失額《+『of』+『名』》 / 〈U〉〈C〉(…に)『負けること』,(…の)敗北;失敗《+『of』+『名』》 / 〈U〉(状態・程度の)『減少』,低下 / 《複数形で》(戦場における)(人の)損害,此傷者数
〈C〉骨 / 〈U〉骨を作っている物質,骨質 / 《複数形で》骨格;死骸(がい) / 〈魚など〉‘の'骨を取る
(魚など)骨を取り除いた / (衣服が)(コルセットなどで)骨で張りをつけた[ような]

UpToDate Contents

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1. 閉経前の骨粗鬆症の疫学および病因 epidemiology and etiology of premenopausal osteoporosis
2. 閉経後の女性における骨粗鬆症のマネージメントの概要 overview of the management of osteoporosis in postmenopausal women
3. 男性における骨粗鬆症の疫学および病因 epidemiology and etiology of osteoporosis in men
4. アロマターゼ阻害剤による骨量減少の評価およびマネージメント evaluation and management of aromatase inhibitor induced bone loss
5. ステロイド誘発性骨粗鬆症の予防および治療 prevention and treatment of glucocorticoid induced osteoporosis

English Journal

Effects of developmental exposure to perfluorooctanoic acid (PFOA) on long bone morphology and bone cell differentiation.

Koskela A1, Finnilä MA2, Korkalainen M3, Spulber S4, Koponen J3, Håkansson H5, Tuukkanen J6, Viluksela M7.
Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2016 Jun 15;301:14-21. doi: 10.1016/j.taap.2016.04.002. Epub 2016 Apr 9.
Perfluorooctanoic acid (PFOA) is a ubiquitous and persistent environmental chemical, which has been used extensively due to its stability and surface tension-lowering properties. Toxicological effects include induction of neonatal mortality and reproductive toxicity. In this study, pregnant C57BL/6
PMID 27068293

The in vivo effects of a fraction from Dioscorea spongiosa on glucocorticoid-induced osteoporosis.

Han N1, Xu J2, Xu F2, Liu Z1, Yin J3.
Journal of ethnopharmacology.J Ethnopharmacol.2016 Jun 5;185:53-9. doi: 10.1016/j.jep.2016.03.033. Epub 2016 Mar 12.
ETHNOPHARMACOLOGICAL RELEVANCE: In traditional Chinese medicines, osteoporosis was considered to be induced by the deficiency of kidney's function. The Rhizoma of Dioscorea spongiosa was one of the kidney tonifying and bone strengthening agent in the traditional usage and previous study had shown th
PMID 26979338

Hyperocclusion stimulates the expression of collagen type XII in periodontal ligament.

Tsuzuki T1, Kajiya H2, T-Goto K3, Tsutsumi T1, Nemoto T1, Okabe K4, Takahashi Y1.
Archives of oral biology.Arch Oral Biol.2016 Jun;66:86-91. doi: 10.1016/j.archoralbio.2016.02.009. Epub 2016 Feb 18.
OBJECTIVES: It is known that excessive mechanical force exerted by hyperocclusion induces occlusal trauma. However, the mechanism of the process remains unclear. In the present study, we employed an in vivo hyperocclusion rodent model to examine morphological and biological mechanisms of occlusal tr
PMID 26930474

Japanese Journal

Prevention of Bone Loss after Ovariectomy in Mice with Preferential Overexpression of the Transcription Factor Paired Box-5 in Osteoblasts

Fujita Hiroyuki,Hinoi Eiichi,Watanabe Takumi [他],Iezaki Takashi,Takamori Misa,Ogawa Shinya,Yoneda Yukio
Biological and Pharmaceutical Bulletin 36(3), 481-484, 2013
… We have recently shown that the transcription factor Paired box-5 (Pax5) promotes bone formation in vivo and osteoblastogenesis in vitro. … Here, we demonstrated the involvement of Pax5 in bone remodeling after ovariectomy (OVX). …
NAID 130003382084

Chlorogenic Acid Inhibits Osteoclast Differentiation and Bone Resorption by Down-Regulation of Receptor Activator of Nuclear Factor Kappa-B Ligand-Induced Nuclear Factor of Activated T Cells c1 Expression

Kwak Sung Chul,Lee Cheol,Kim Ju-Young [他],Oh Hyun Mee,So Hong-Seob,Lee Myeung Su,Rho Mun Chual,Oh Jaemin
Biological and Pharmaceutical Bulletin 36(11), 1779-1786, 2013
… Excessive osteoclastic bone resorption plays a critical role in inflammation-induced bone loss such as rheumatoid arthritis and periodontal bone erosion. … Therefore, identification of osteoclast targeted-agents may be a therapeutic approach to the treatment of pathological bone loss. …
NAID 130003361551

運動刺激による骨組織の形成と吸収

田巻弘之
日本運動生理学雑誌 19(2), 53-57, 2012-07-20
… Bone mass is controlled by the balance between bone formation and bone resorption. … In bone remodeling process, bone metabolism is achieved by the co-ordinated actions of osteoclasts, osteoblasts, osteocytes within the bone matrix and lining cells that cover the surface of bone. …
NAID 110009479351