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1. 骨格の正常な発達および骨形成ならびに骨吸収の調節 normal skeletal development and regulation of bone formation and resorption
2. ビスホスホネートの薬理学 pharmacology of bisphosphonates
3. 甲状腺機能亢進症および甲状腺ホルモン療法による骨疾患 bone disease with hyperthyroidism and thyroid hormone therapy
4. 骨転移の機序 mechanisms of bone metastases
5. 骨の巨大細胞腫瘍 giant cell tumor of bone

Is there a relationship between solubility and resorbability of different calcium phosphate phases in vitro?

Wu VM1, Uskoković V1.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Oct;1860(10):2157-68. doi: 10.1016/j.bbagen.2016.05.022. Epub 2016 May 19.
BACKGROUND: Does chemistry govern biology or it is the other way around - that is a broad connotation of the question that this study attempted to answer.METHOD: Comparison was made between the solubility and osteoclastic resorbability of four fundamentally different monophasic calcium phosphate (CP
PMID 27212690

Mechanical stress regulates osteogenic differentiation and RANKL/OPG ratio in periodontal ligament stem cells by the Wnt/β-catenin pathway.

Zhang L1, Liu W1, Zhao J2, Ma X3, Shen L3, Zhang Y1, Jin F4, Jin Y5.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Oct;1860(10):2211-9. doi: 10.1016/j.bbagen.2016.05.003. Epub 2016 May 3.
BACKGROUND: The balance between osteoblastic and osteoclastic activity is critical in orthodontic tooth movement (OTM). Mesenchymal stem cells (MSCs) play an important role in maintaining bone homeostasis, and periodontal ligament stem cells (PDLSCs) are tissue-specific MSCs in the periodontal ligam
PMID 27154288

Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases.

Watanabe K1, Tominari T2, Hirata M3, Matsumoto C3, Maruyama T4, Murphy G5, Nagase H6, Miyaura C7, Inada M8.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Sep 9;478(1):154-61. doi: 10.1016/j.bbrc.2016.07.075. Epub 2016 Jul 19.
The metastasis of tumors to bone is known to be promoted by prostaglandin E2 (PGE2) produced by the tumor host stromal tissue. Although bone metastases frequently occur in prostate cancer patients, the significance of PGE2 in stromal responses to the tumor is not known. In this study, we report that
PMID 27450806

Comparative study on the resorbability and dissolution behavior of octacalcium phosphate, β-tricalcium phosphate, and hydroxyapatite under physiological conditions

Accumulation and washout of 99mTc-sestamibi in osteoarthritic subchondral bone may indicate increased osteoclastic activity accompanying microfractures: a case study