癌遺伝子産物v-Cbl
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- the 22nd letter of the Roman alphabet (同)v
- a gene that disposes normal cells to change into cancerous tumor cells (同)transforming_gene
PrepTutorEJDIC
- carbonの化学記号
- 蛋白(たんばく)質
- vanadium の化学記号
- verb / verso / 《話》very / velocity / volt[s] / volume / vide
UpToDate Contents
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English Journal
- Methylation of TET2, CBL and CEBPA in Ph-negative myeloproliferative neoplasms.
- Chim CS, Wan TS, Fung TK, Wong KF.SourceDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong. jcschim@hku.hk
- Journal of clinical pathology.J Clin Pathol.2010 Oct;63(10):942-6. Epub 2010 Jul 29.
- A loss-of-function mutation of TET2, CBL and CEBPA has been implicated in the pathogenesis or leukaemic transformation of myeloproliferative neoplasm. As tumour suppressor genes may potentially be inactivated by promoter hypermethylation, the authors studied the methylation status of these genes in
- PMID 20671051
- Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.
- Kales SC, Ryan PE, Nau MM, Lipkowitz S.SourceLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4256, USA.
- Cancer research.Cancer Res.2010 Jun 15;70(12):4789-94. Epub 2010 May 25.
- Cbl was originally discovered in 1989 as the cellular homolog of the v-Cbl oncogene, the transforming gene of the Cas NS-1 murine retrovirus that causes myeloid leukemia and lymphomas in mice. Cbl is a member of a family of RING finger ubiquitin ligases that negatively regulate signaling by tyrosine
- PMID 20501843
Related Links
- The v-cbl oncogene is the transforming gene of the murine Cas NS-1 retrovirus which induces pre-B cell lymphomas and ... that v-cbl was generated by a large truncation that removed 60% of the C-terminus of the corresponding protein. ...
★リンクテーブル★
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- 英
- oncogene protein v-Cbl
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- 関
- oncogene product、oncoprotein
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対
- 関
- pair、paired、pairwise、versus