nicomol

ニコモール

English Journal

  • [Niceritrol decreases serum phosphate levels in chronic hemodialysis patients].
  • Shimoda K, Akiba T, Matsushima T, Rai T, Abe K, Hoshino M.SourceSeisyokai Hijiribashi Clinic, Tokyo, Japan.
  • Nihon Jinzo Gakkai shi.Nihon Jinzo Gakkai Shi.1998 Jan;40(1):1-7.
  • Since phosphorus retention in hemodialysis (HD) patients is known to be an important factor in the development of secondary hyperparathyroidism and renal osteodystrophy, phosphate binders have been needed for the control of serum phosphate levels (P). However, the calcium-containing phosphate binder
  • PMID 9513376
  • Protective effects of various drugs on adriamycin (doxorubicin)-induced toxicity and microsomal lipid peroxidation in mice and rats.
  • Shinozawa S, Gomita Y, Araki Y.SourceDepartment of Hospital Pharmacy, Okayama University Medical School, Japan.
  • Biological & pharmaceutical bulletin.Biol Pharm Bull.1993 Nov;16(11):1114-7.
  • The protective effects of clinically used drugs on the toxicity and microsomal lipid peroxidation induced by doxorubicin (adriamycin, ADM), an anthracycline type antitumor agent, were studied in mice and rats. Regarding the effects of anthracyclines (aclarubicin, ACL; daunorubicin, DAU; ADM; epirubi
  • PMID 8312867

Japanese Journal

  • Niceritrolは慢性維持血液透析患者において血清無機リン濃度を低下させる
  • 下田 研二,秋葉 隆,松島 照彦,頼 建光,阿部 薫,星野 正信
  • The Japanese journal of nephrology = / 日本腎臓学会 [編集] 40(1), 1-7, 1998-01-25
  • NAID 10008361959
  • Niceritrolは慢性維持血液透析患者において血清無機リン濃度を低下させる
  • 下田 研二,秋葉 隆,松島 照彦,頼 建光,阿部 薫,星野 正信
  • 日本腎臓学会誌 40(1), 1-7, 1998
  • … The aim of the present study was to assess the mechanism of the P-lowering effect of NT in comparison with nicomol (NC), another prodrug of nicotinic acid. …
  • NAID 130004170428
  • Protective Effects of Various Drugs on Adriamycin (Doxorubicin)-Induced Toxicity and Microsomal Lipid Peroxidation in Mice and Rats
  • 篠沢 真哉,五味田 裕,荒木 泰典
  • Biological and Pharmaceutical Bulletin 16(11), 1114-1117, 1993-11-15
  • … (Co Q), 235% for dextran sulfate (DS), 123% for dipyridamole, 121% for flavin adenine dinucleotide, 213% for reduced glutathion, 155% for inositol nicotinate, 157% for nicardipin and 297% for nicomol. …
  • NAID 110003663257

Related Links

Nicomol is a medicine available in a number of countries worldwide. A list of US medications equivalent to Nicomol is available on the Drugs.com website. ... Scheme Rec.INN CAS registry number (Chemical Abstracts Service)
脂質代謝・末梢血行改善剤コレキサミン錠 (製薬会社:杏林製薬株式会社)脂質代謝改善作用があり、消化管からのコレステロール、中性脂肪の吸収を抑制し、血中脂質を低下させます。また、手足の末梢血管を拡張させるとともに血小板 ...



★リンクテーブル★
リンク元ニコチン酸系薬」「ニコモール

ニコチン酸系薬」

  [★]

  • あまり使われないらしい

ニコチン酸系薬

特徴

  • 肝臓からのVLDL分泌を抑制しLDLの血中濃度を減少させる (SPC.353)
  • 血管拡張作用を持つ

構造

作用機序

  • 遊離脂肪酸の動員↓。肝でのVLDL合成↓。→LPL↑→VLDL-TG分解↑→TG↓ Cho排泄↑ LP(a)
  • コレステロール排泄促進作用

薬理作用

  • 血清TG:低下
  • Cho排泄:促進
  • 血清LP(a):低下

動態

適応

注意

禁忌

副作用

  • 皮膚障害(発赤(顔面紅潮←アスピリンで軽減)、かゆみ)

相互作用

ニコモール」

  [★]

nicomol
コレキサミンアトミラートコトモール