niceritrol


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/26 01:52:37」(JST)

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English Journal

  • A novel method aimed at counteracting the side effects caused by prostaglandin e2 deficiency during non-steroidal anti-inflammatory drug therapy.
  • Gargaun S, Gargaun L1.
  • Anti-inflammatory & anti-allergy agents in medicinal chemistry.Antiinflamm Antiallergy Agents Med Chem.2014;13(2):121-7.
  • BACKGROUND: Prostaglandin E2 (PGE2) plays key physiological roles within the body's organs and the systemic environment. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the biosynthesis of PGE2, which can lead to global PGE2 deficiency, resulting in serious side effects in the gastrointestina
  • PMID 24383936
  • Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol.
  • Hamatani H1, Hiromura K, Kobatake K, Yoshida H, Kobayashi S, Yoneda N, Kayakabe K, Matsumoto T, Kuroiwa T, Ueki K, Nojima Y.
  • Clinical and experimental nephrology.Clin Exp Nephrol.2010 Dec;14(6):619-24. doi: 10.1007/s10157-010-0333-9. Epub 2010 Sep 15.
  • We report two patients, a daughter and a mother, with lipoprotein glomerulopathy (LPG) who were successfully treated with niceritrol. Both patients carried a mutation in the apolipoprotein E (apoE) gene known as ApoE Tokyo/Maebashi. The daughter was found to have proteinuria at the age of 4 years. F
  • PMID 20842518
  • Binder blinders-niacin of omission?
  • Bostom AG.
  • American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2010 Apr;55(4):628-30. doi: 10.1053/j.ajkd.2009.12.015. Epub 2010 Jan 15.
  • PMID 20079958

Japanese Journal

  • Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol
  • HAMATANI Hiroko,HIROMURA Keiju,KOBATAKE Keiko,YOSHIDA Hiroaki,KOBAYASHI Satsuki,YONEDA Naohiro,KAYAKABE Ken,MATSUMOTO Takayuki,KUROIWA Takashi,UEKI Kazue,NOJIMA Yoshihisa
  • Clinical and experimental nephrology 14(6), 619-624, 2010-12-01
  • NAID 10029321422
  • Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia : a randomized trial
  • 血液透析患者におけるニセリトロール服用時の血中ニコチン酸濃度
  • 雑賀 保至,児玉 直也,木村 圭吾,藤井 良一,大谷 晴久,宗 正敏,味村 啓司,前田 孝夫,湯川 進
  • The Japanese journal of nephrology = / 日本腎臓学会 [編集] 41(4), 430-435, 1999-06-25
  • NAID 10005248201

Related Links

Niceritrol. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Niceritrol. Systematic (IUPAC) name ... Niceritrol is a niacin derivative used as a hypolipidemic agent. v · t · e · Lipid modifying agents (C10). GI tract · Cholesterol ...
Scand J Clin Lab Invest. 1996 Jul;56(4):359-65. Dose-dependent effect of niceritrol on plasma lipoprotein-a. Teramoto T, Yamada N, Shimano H, Oka Y, Itakura H, Saito Y, Morisaki N, Shirai K, Ishikawa T, Tada N, Ito H, Yamanouchi T, ...


Related Pictures

 名:ニセリトロール (NiceritrolNiceritrol - Wikipedia, the free  Niceritrol; Perycit; SK 1; SK 1酯 niceritrol 烟 酸 肌 醇 酯 ペリシット錠250mg 一般名:ニ Niceritrol; Tetranicotinato de



★リンクテーブル★
リンク元ニコチン酸系薬」「ニセリトロール

ニコチン酸系薬」

  [★]

  • あまり使われないらしい

ニコチン酸系薬

特徴

  • 肝臓からのVLDL分泌を抑制しLDLの血中濃度を減少させる (SPC.353)
  • 血管拡張作用を持つ

構造

作用機序

  • 遊離脂肪酸の動員↓。肝でのVLDL合成↓。→LPL↑→VLDL-TG分解↑→TG↓ Cho排泄↑ LP(a)
  • コレステロール排泄促進作用

薬理作用

  • 血清TG:低下
  • Cho排泄:促進
  • 血清LP(a):低下

動態

適応

注意

禁忌

副作用

  • 皮膚障害(発赤(顔面紅潮←アスピリンで軽減)、かゆみ)

相互作用

ニセリトロール」

  [★]

niceritrol
ペリシット