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1. 慢性肝疾患に対する組織学的スコアリングシステムhistologic scoring systems for chronic liver disease [show details]
… The histologic grading systems for chronic hepatitis are also applied to autoimmune hepatitis because, as of yet, there is no formal histological classification system available specifically for autoimmune …
2. 肝疾患患者における手術リスクの評価assessing surgical risk in patients with liver disease [show details]
… patients with chronic hepatitis correlates with the clinical, biochemical, and histologic severity of disease. Patients with symptomatic and histologically severe chronic hepatitis have increased… correlate well with the Child-Turcotte and the CP classifications of cirrhosis: In one study from 1984,…
3. 成人における肝硬変：病態、臨床症状、および診断cirrhosis in adults etiologies clinical manifestations and diagnosis [show details]
…larger than 3 mm, was believed to be secondary to chronic viral hepatitis. Although important from a historic perspective, the morphological classification system has a number of limitations and has thus …
4. 胆管癌の疫学、病因、および分類epidemiology pathogenesis and classification of cholangiocarcinoma [show details]
…changes in ICD (International Classification of Disease) classification . In addition, at least some of the increase in intrahepatic cholangiocarcinomas may be attributable to new diagnostic methods for obstructive …
5. 慢性C型肝炎ウイルス感染への抗ウイルス療法における患者の評価および選択patient evaluation and selection for antiviral therapy for chronic hepatitis c virus infection [show details]
…inflection point in our long term effort to control the silent epidemic of chronic hepatitis C virus infection (HCV). With the advent of new medicines, the vast majority of patients with HCV infection who have …

English Journal

Complement Component 3 as a Surrogate Hallmark for Metabolic Abnormalities in Patients with Chronic Hepatitis C.

Himoto T, Hirakawa E, Fujita K, Sakamoto T, Nomura T, Morishita A, Yoneyama H, Haba R, Masaki T.
Annals of clinical and laboratory science. 2019 Jan;49(1)79-88.
We investigated the correlation between serum complement component 3 (C3) levels and metabolic and histological abnormalities in patients with chronic hepatitis C (CH-C). Obesity and insulin resistance were estimated by calculating body mass index (BMI) and the values of the homeostasis model for as
PMID 30814081

Development of a hepatocellular carcinoma in a chronic hepatitis C patient 18 years after achieving a sustained virological response to interferon therapy: case report and literature review.

Saito M, Seo Y, Yano Y, Miki A, Morinaga Y, Itoh T, Yoshida M, Azuma T.
Clinical journal of gastroenterology. 2012 Apr;5(2)119-26.
We report on a chronic hepatitis C patient who developed hepatocellular carcinoma (HCC) 18 years after achieving a sustained virological response (SVR) to interferon therapy. We also review other reports of patients who developed HCC a long time after interferon therapy. The patient was a 67-year-o
PMID 26182154

Selenium deficiency is associated with insulin resistance in patients with hepatitis C virus-related chronic liver disease.

Himoto T, Yoneyama H, Kurokohchi K, Inukai M, Masugata H, Goda F, Haba R, Watababe S, Kubota S, Senda S, Masaki T.
Nutrition research (New York, N.Y.). 2011 Nov;31(11)829-35.
The relationship between selenium (Se) deficiency and insulin resistance has not much been established in persistent hepatitis C virus (HCV) infection, although Se deficiency is often observed in patients with liver cirrhosis. We hypothesized that the decreased serum Se levels were associated with t
PMID 22118753

Japanese Journal

インターフェロン治療後８年目に診断された肝細胞癌の１例

飯田拓,世古口務,山本敏雄,中村菊洋,櫻井洋至,伊藤史人
日本臨床外科学会雑誌 62(6), 1492-1496, 2001
症例は69歳男性. 1992年C型慢性肝炎に対しインターフェロン (IFN) 治療を施行され,トランスアミナーゼは持続正常化,血中HCV-RNAも持続陰性化し,著効した.治療前後の肝組織像も新犬山分類F3A2からF2A1に改善した. 1995年までの画像検査では異常を認めず,以後患者の自己判断にて診察が中断されていた. 2000年著効8年後肺気腫にて他院通院中,軽度の肝機能障害を指摘.各種検査にて …
NAID 130003602518

New Inuyama classification; new criteria for histological assessment of chronic hepatitis^1

ICHIDA Fumihiro,TSUJI Takao,OMATA Masao,ICHIDA Takafumi,INOUE Kyouichi,KAMIMURA Tomoteru,YAMADA Goutarou,HINO Kunihiko,YOKOSUKA Osamu,SUZUKI Hiroshi
International hepatology communications 6(2), 112-119, 1996-12
NAID 10005908563

「新犬山分類」

　　[★]

英: new Inuyama classification of chronic hepatitis
同: 慢性肝炎

1

線維化の程度	壊死・炎症所見の程度
F0 ：線維化なし	A0 ：壊死・炎症所見なし
F1 ：門脈域の線維性拡大	A1 ：軽度の壊死・炎症所見
F2 ：線維性架橋形成	A2 ：中等度の壊死・炎症所見
F3 ：小葉のひずみを伴う線維性架橋形成	A3 ：高度の壊死・炎症所見
F4 ：肝硬変