WordNet

act so as to bring into existence; "effect a change"
a symptom caused by an illness or a drug; "the effects of sleep loss"; "the effect of the anesthetic"
(of a law) having legal validity; "the law is still in effect" (同)force
the central meaning or theme of a speech or literary work (同)essence, burden, core, gist
an impression (especially one that is artificial or contrived); "he just did it for effect"
produce; "The scientists set up a shock wave" (同)effectuate, set_up
property of a personal character that is portable but not used in business; "she left some of her personal effects in the house"; "I watched over their effects until they returned" (同)personal_effects

PrepTutorEJDIC

〈C〉〈U〉『結果』 / 〈C〉〈U〉(…への)『効果』,効きめ,影響《+『on』(『upon』)+『名』》 / 〈C〉(色・音・形などの)印象,感銘 / 《複数形で》品物;身の回り品;動産,財産 / (結果として)…‘を'『もたらす』;〈目的など〉‘を'果たす,遂行する

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Deng A1, Liang X1, Sun Y2, Xiang Y1, Yang J1, Yan J1, Sun W2.
Acta oto-laryngologica.Acta Otolaryngol.2015 Nov;135(11):1132-7. doi: 10.3109/00016489.2015.1064996. Epub 2015 Jul 4.
CONCLUSION: Scopolamine, a tropane alkaloid drug that mainly acts as an antagonist of muscarinic acetylcholine receptors, was found to reduce the local field potentials (LFP) of auditory cortex (AC) evoked by tone and gap-offsets whose effects may compensate the cortical hyperexcitability related to
PMID 26144861

New multifunctional melatonin-derived benzylpyridinium bromides with potent cholinergic, antioxidant, and neuroprotective properties as innovative drugs for Alzheimer's disease.

Luo XT1, Wang CM2, Liu Y3, Huang ZG4.
European journal of medicinal chemistry.Eur J Med Chem.2015 Oct 20;103:302-11. doi: 10.1016/j.ejmech.2015.08.052. Epub 2015 Sep 5.
A novel series of melatonin-derived benzylpyridinium bromides have been designed, synthesized, and evaluated as multi-functional anti-AD agents with cholinesterase inhibitory, antioxidant, and neuroprotective activities. In vitro studies showed that most of these compounds exhibited potent inhibito
PMID 26363866

Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders.

Terry AV Jr1, Callahan PM2, Hernandez CM2.
Biochemical pharmacology.Biochem Pharmacol.2015 Oct 15;97(4):388-98. doi: 10.1016/j.bcp.2015.07.027. Epub 2015 Jul 29.
The challenges associated with developing more effective treatments for neurologic and psychiatric illness such as Alzheimer's disease and schizophrenia are considerable. Both the symptoms and the pathophysiology of these conditions are complex and poorly understood and the clinical presentations ac
PMID 26231940

佐藤しづ子,笹野高嗣
薬学雑誌. 乙号 135(6), 783-787, 2015
… Drugs for dry mouth such as M3, a muscarinic agonist, have been widely used: however, these drugs have serious side effects, such as vomiting, sweating and/or digestive disorders. … We have demonstrated that umami stimulation increases saliva from both minor- and major salivary-glands, and that the effect is longer-lasting than with the other four basic tastes. …
NAID 130005071783

Force-inhibiting effect of Ser/Thr protein phosphatase 2A inhibitors on bovine ciliary muscle

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Journal of Smooth Muscle Research 51(0), 10-21, 2015
… Ciliary muscle is a smooth muscle characterized by a rapid response to muscarinic receptor stimulation and sustained contraction. …
NAID 130005071307

Nicotinic Acetylcholine Receptors Mediate the Suppressive Effect of an Injection of Diluted Bee Venom into the GV3 Acupoint on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats

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Biological and Pharmaceutical Bulletin 38(5), 710-714, 2015
… Although we previously demonstrated the suppressive effect of BV injection on oxaliplatin-induced cold allodynia in rats, its neurochemical mechanism remained unclear. … This study investigates whether and how the cholinergic system mediates the relieving effect of BV injection on cold allodynia in oxaliplatin-administered rats. …
NAID 130005068084