- 同
- MCT8
WordNet
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- a long truck for carrying motor vehicles (同)car transporter
- a crane for moving material with dispatch as in loading and unloading ships
PrepTutorEJDIC
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 自動車運搬用大型トラック
UpToDate Contents
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English Journal
- Iodine deficiency up-regulates monocarboxylate transporter 8 expression of mouse thyroid gland.
- Hu Z1, Zhuo X2, Shi Y2, Liu X2, Yuan J2, Li L2, Sun Y3.
- Chinese medical journal.Chin Med J (Engl).2014 Dec;127(23):4071-6.
- BACKGROUND: Iodine deficiency is a major factor affecting thyroid auto-regulation, the quantity of iodine may greatly influence the synthesis of thyroid hormones (THs). It has long been believed that TH enters the cell through passive diffusion. Recent studies have suggested that several transporter
- PMID 25430451
- Endurance Training Alters Skeletal Muscle MCT Contents in T2DM Men.
- Opitz D1, Lenzen E1, Schiffer T2, Hermann R1, Hellmich M3, Bloch W1, Brixius K1, Brinkmann C1.
- International journal of sports medicine.Int J Sports Med.2014 Dec;35(13):1065-1071. Epub 2014 Jul 10.
- Patients suffering from type 2 diabetes mellitus (T2DM) often exhibit chronic elevated lactate levels which can promote peripheral insulin resistance by disturbing skeletal muscle insulin-signaling. Monocarboxylate transporter (MCT) proteins transfer lactate molecules through cellular membranes. MCT
- PMID 25009968
- In Vitro and Mouse Studies Supporting Therapeutic Utility of Triiodothyroacetic Acid in MCT8 Deficiency.
- Kersseboom S1, Horn S, Visser WE, Chen J, Friesema EC, Vaurs-Barrière C, Peeters RP, Heuer H, Visser TJ.
- Molecular endocrinology (Baltimore, Md.).Mol Endocrinol.2014 Nov 12:me20141135. [Epub ahead of print]
- Monocarboxylate transporter 8 (MCT8) transports thyroid hormone (TH) across the plasma membrane. Mutations in MCT8 result in the Allan-Herndon-Dudley syndrome, comprising severe psychomotor retardation and elevated serum T3 levels. Because the neurological symptoms are most likely caused by a lack o
- PMID 25389909
Japanese Journal
- Regulation of the Expression and Activity of Glucose and Lactic Acid Metabolism-Related Genes by Protein Kinase C in Skeletal Muscle Cells
- Otake Sho,Kobayashi Masaki,Narumi Katsuya,Sasaki Shotaro,Kikutani Yurika,Furugen Ayako,Watanabe Meguho,Takahashi Natsuko,Ogura Jiro,Yamaguchi Hiroaki,Iseki Ken
- Biological and Pharmaceutical Bulletin 36(9), 1435-1439, 2013
- … Furthermore, chetomin, a hypoxia-inducible factor 1 (HIF-1) inhibitor, completely abrogated the increment of LDH mRNA level and activity as well as monocarboxylate transporter (MCT) 4, a lactic acid efflux transporter. …
- NAID 130003361512
- Monocarboxylate transporter and lactate metabolism
- Kitaoka Yu,Hoshino Daisuke,Hatta Hideo
- The Journal of Physical Fitness and Sports Medicine 1(2), 247-252, 2012
- … The movement of lactate across the plasma membrane is facilitated by a family of monocarboxylate transporters (MCTs). …
- NAID 130001930864
- Possible Pathway of Na+ Flux into Mitochondria in Ischemic Heart
- Tanonaka Kouichi,Motegi Kanataka,Arino Toru [他],Marunouchi Tetsuro,Takagi Norio,Takeo Satoshi
- Biological and Pharmaceutical Bulletin 35(10), 1661-1668, 2012
- … To mimic induction of mitochondrial Na+ overload in vitro, isolated mitochondria were incubated with 6.25 to 50 mM NaCl or sodium lactate, a metabolite of anaerobic glycolysis, in the presence and absence of a mitochondrial Na+/Ca2+ exchanger inhibitor CGP37157 and a monocarboxylate transporter (MCT) inhibitor α-cyano-4-hydroxy cinnamic acid (CHCA). …
- NAID 130001872354
Related Links
- MCT8(Monocarboxylate transporter 8) 異常症における乳児期のアシドーシス 野口 篤子 秋田大学 医学部 生殖発達医学講座 小児科学分野 高橋 郁子 秋田大学 医学部 生殖発達医学講座 小児科学分野 小山田 美香 秋田大学 医学部 ...
- Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and ... Monocarboxylate transporter 8 deficiency (MCT8 deficiency) [MIM: 300523] ...
★リンクテーブル★
[★]
- 同
- monocarboxylate transporter 8
[★]
- 関
- bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation
[★]
トランスポーター
- 関
- translocator、transport protein、transporter protein