lactate dehydrogenase isozymes

乳酸脱水素酵素アイソザイム

WordNet

1. a salt or ester of lactic acid

PrepTutorEJDIC

1. 乳を出す

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• 1. 乳酸脱水素酵素欠損症 lactate dehydrogenase deficiency
• 2. びまん性大細胞型B細胞性リンパ腫の予後 prognosis of diffuse large b cell lymphoma
• 3. 新生児における胸水の病因、臨床症状、診断および評価 etiology clinical manifestations diagnosis and evaluation of pleural effusions in the neonate
• 4. 進行期（III/IV）濾胞性リンパ腫の初期治療 initial treatment of advanced stage iii iv follicular lymphoma
• 5. 移植後リンパ球増殖性疾患の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of post transplant lymphoproliferative disorders

English Journal

• HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition.

• Ekman M1, Uvelius B2, Albinsson S3, Swärd K3.
• Laboratory investigation; a journal of technical methods and pathology.Lab Invest.2014 May;94(5):557-68. doi: 10.1038/labinvest.2014.48. Epub 2014 Mar 3.
• Prior work demonstrated increased levels of hypoxia-inducible factor-1α (HIF-1α) in the bladder following outlet obstruction, associated with bladder growth and fibrosis. Here we hypothesized that HIF induction in outlet obstruction also switches energetic support of contraction from mitochondrial
• PMID 24589856

• NMR-based evaluation of the metabolic profile and response to dichloroacetate of human prostate cancer cells.

• Kailavasan M1, Rehman I, Reynolds S, Bucur A, Tozer G, Paley M.
• NMR in biomedicine.NMR Biomed.2014 May;27(5):610-6. doi: 10.1002/nbm.3101. Epub 2014 Mar 17.
• The aim of this study was to evaluate the metabolic profile of human prostate cancer cells that have different metastatic potential and to determine their response to dichloroacetate (DCA) using NMR technology. Two isogenic human prostate cancer cell lines, differing in their metastatic potential [L
• PMID 24639007

• The Adaptive Cline at LDH (Lactate Dehydrogenase) in Killifish Fundulus heteroclitus Remains Stationary After 40 Years of Warming Estuaries.

• Bell TM1, Strand AE, Sotka EE.
• The Journal of heredity.J Hered.2014 Mar 11. [Epub ahead of print]
• Since the 1970s, water temperatures along the Atlantic seaboard of the United States have risen by an average of 0.5 °C in summer months and 2.2 °C in winter months. In response, the distribution and abundance of several nearshore species have changed dramatically, but no study has attempted to do
• PMID 24620002

Japanese Journal

• Nudix Hydrolase Controls Nucleotides and Glycolytic Mechanisms in Hypoxic Aspergillus nidulans

• SHIMIZU Motoyuki,TAKAYA Naoki
• Bioscience, biotechnology, and biochemistry 77(9), 1888-1893, 2013-09-23
• … Among three nudix hydrolase isozymes, NdxA transcription was up-regulated under oxygen (O2)-limited conditions. … Under O2-limited conditions, NdxAΔ decreased glucose consumption, the production of ethanol and lactate, cellular ATP levels, and growth as compared with WT. … Steady-state kinetics indicated that NADH and ADP-ribose competitively inhibited fungal GAP dehydrogenase (GAPDH) with Ki values of 34- and 55-µM, respectively. …
• NAID 10031202740

• Overexpression of Interleukin 2 Receptor, Thymidine Kinase and Immunoglobulin-Associated Alpha-1 Messenger RNA in a Clinical Case of Enzootic Bovine Leukosis

• TAWFEEQ Mohammad Monir,TAGAWA Michihito,ITOH Yuuki [他],SUGIMOTO Kazuya,KOBAYASHI Yoshiyasu,INOKUMA Hisashi
• Journal of Veterinary Medical Science 74(9), 1203-1206, 2012
• … Increased total lactate dehydrogenase (LDH) activity, isozymes of LDH-2 and LDH-3 activities and thymidine kinase activity were observed. …
• NAID 130001879756

• Overexpression of Interleukin 2 Receptor, Thymidine Kinase and Immunoglobulin-Associated Alpha-1 Messenger RNA in a Clinical Case of Enzootic Bovine Leukosis

• TAWFEEQ Mohammad Monir,TAGAWA Michihito,ITOH Yuuki,SUGIMOTO Kazuya,KOBAYASHI Yoshiyasu,INOKUMA Hisashi,古林 与志安,猪熊 壽
• Journal of Veterinary Medical Science 74(9), 1203-1206, 2012
• … Increased total lactate dehydrogenase (LDH) activity, isozymes of LDH-2 and LDH-3 activities and thymidine kinase activity were observed. …
• NAID 120005609031

Related Links

• Structural adaptations of lactate dehydrogenase isozymes.

Evolutionary relationships of vertebrate lactate dehydrogenase isozymes A4 (muscle), B4 (heart), and C4 (testis). J Biol Chem. 1983 Jun 10; 258(11):7029-32. [J Biol Chem. 1983] Evolution of lactate dehydrogenase-A homologs of ...

• Early diagnosis of radiodermatitis using lactate ...

Native-polyacrylamide gel electrophoresis zymograms (a-g) and western blot analysis (h, i) of the lactate dehydrogenase (LDH) isozymes of SKH1-hr mice. Electrophoretic patterns of the skeletal muscle (a), heart (b), kidney (c...

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★リンクテーブル★

リンク元	「乳酸脱水素酵素アイソザイム」「LDH」
関連記事	「isozyme」「lactating」「dehydrogenase」「dehydrogenases」「lactate dehydrogenase」

「乳酸脱水素酵素アイソザイム」

　　[★]

英

lactate dehydrogenase isozyme, lactate dehydrogenase isozymes

同

LDアイソザイム

関

乳酸脱水素酵素 LDH

OLM.257改変

• LDH1,LDH2の上昇：溶血、心筋障害、骨格筋(変性)、代謝亢進・代謝低下

• 心筋梗塞、巨赤芽球性貧血、溶血性貧血、筋ジストロフィー、クッシング病、甲状腺機能低下症

• LDH2,LDH3の上昇：血液疾患、悪性腫瘍、膵臓(炎症)

• 白血病、リンパ腫、膵炎、進行癌

• LDH4,LDH5の上昇：血液うっ滞、肝障害、骨格筋(炎症)

• うっ血性心不全、ウイルス性肝炎、中毒性肝炎、肝硬変、尿毒症、多発性筋炎

「LDH」

　　[★]

• 乳酸脱水素酵素 lactate dehydrogenase
• 乳酸脱水素酵素アイソザイム lactate dehydrogenase isozymes
• 腰椎椎間板ヘルニア lumbar disc herniation

「isozyme」

　　[★]

アイソザイム、イソ酵素

関

isoenzyme、isozymic

「lactating」

　　[★]

• n.

• 授乳中、泌乳

関

lactation

「dehydrogenase」

　　[★] 脱水素酵素 デヒドロゲナーゼ

「dehydrogenases」

　　[★] 脱水素酵素 デヒドロゲナーゼ

「lactate dehydrogenase」

　　[★] 乳酸脱水素酵素 LDH