腸上皮化生
WordNet
- of or relating to or inside the intestines; "intestinal disease" (同)enteric, enteral
PrepTutorEJDIC
- 腸[内]の
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/05/14 13:27:52」(JST)
[Wiki en表示]
Intestinal metaplasia (top middle of image) of the gastric antrum and adenocarcinoma of the stomach (left/centre of image). H&E stain.
Intestinal metaplasia is the transformation (metaplasia) of epithelium, usually of the stomach or the esophagus , to a type that bears some resemblance to the intestine as seen in Barrett's esophagus. Chronic infection caused by H. pylori infection in the stomach and GERD in the esophagus are seen as the primary instigators of metaplasia and subsequent adenocarcinoma formation. Initially, the transformed eptithelium bears resemblance to the small intestine; in the later stages, the epithelium resembles the colon. It is characterized by the appearance of goblet cells and expression of intestinal cell markers such as Cdx2.
External links [edit]
- Intestinal metaplasia (definition) - mondofacto.com.
UpToDate Contents
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- 1. 化生(慢性)萎縮性胃炎 metaplastic chronic atrophic gastritis
- 2. バレット食道およびその癌化の病因 pathogenesis of barretts esophagus and its malignant transformation
- 3. 胃癌の危険因子 risk factors for gastric cancer
- 4. 胃癌スクリーニングおよび予防 screening and prevention of gastric cancer
- 5. バレット食道の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of barretts esophagus
English Journal
- Interobserver variation in assessment of gastric premalignant lesions: higher agreement for intestinal metaplasia than for atrophy.
- Leja M, Funka K, Janciauskas D, Putnins V, Ruskule A, Kikuste I, Kojalo U, Tolmanis I, Misins J, Purmalis K, Pimanov S, Makarenko J, Kupcinskas L, Vikmanis U.SourceaFaculty of Medicine, University of Latvia, Riga, Latvia bDigestive Diseases Centre GASTRO, Riga, Latvia cDepartment of Research, Riga East University hospital, Riga, Latvia dFaculty of Medicine, University of Latvia, Riga, Latvia eDepartment of Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania fFaculty of Medicine, University of Latvia, Riga, Latvia gAcademic Histology laboratory, SIA, Riga, Latvia hDepartment of Endoscopy and Gastroenterology, Digestive Diseases Centre GASTRO, Riga, Latvia iFaculty of Economics and Management, University of Latvia, Riga, Latvia jDepartment of Internal Medicine, Vitebsk State Medical University, Vitebsk, Belarus kGastroenterology Research Institute, Lithuanian University of Health Sciences, Kaunas, Lithuania.
- European journal of gastroenterology & hepatology.Eur J Gastroenterol Hepatol.2013 Jun;25(6):694-699.
- BACKGROUND: Either atrophy or intestinal metaplasia of the gastric mucosa are considered premalignant lesions. The new operative link for gastritis assessment staging system is based on the detection of atrophy, and the operative link for assessment of intestinal metaplasia staging system is based o
- PMID 23337173
- Pathology of gastric cancer and its precursor lesions.
- Yakirevich E, Resnick MB.SourceDepartment of Pathology, Rhode Island Hospital, APC-12, 593 Eddy Street, Providence, RI 02903, USA.
- Gastroenterology clinics of North America.Gastroenterol Clin North Am.2013 Jun;42(2):261-84. doi: 10.1016/j.gtc.2013.01.004. Epub 2013 Mar 1.
- Gastric cancers are a histologically heterogenous group of neoplasms arising from unique epidemiologic and molecular backgrounds. There is accumulating evidence that the intestinal type of gastric adenocarcinoma develops through a multistep process beginning with chronic gastritis triggered primaril
- PMID 23639640
- The corpus-predominant gastritis index may serve as an early marker of Helicobacter pylori-infected patients at risk of gastric cancer.
- Tsai YC, Hsiao WH, Yang HB, Cheng HC, Chang WL, Lu CC, Sheu BS.SourceInstitute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
- Alimentary pharmacology & therapeutics.Aliment Pharmacol Ther.2013 May;37(10):969-78. doi: 10.1111/apt.12291. Epub 2013 Apr 2.
- BACKGROUND: To eradicate Helicobacter pylori before the occurrence of precancerous changes is important to prevent gastric carcinogenesis.AIM: To validate whether the corpus-predominant gastritis index (CGI) can serve as an early marker to identify the H. pylori-infected patients at risk of gastric
- PMID 23550594
Japanese Journal
- Helicobacter pylori感染性胃炎により惹起される胃粘膜上皮のActivation-induced cytidine deaminase(AID)発現 : 胃癌ハイリスク群との関連 (特集 炎症と消化器癌)
- 胃癌ハイリスク群に対するH.pylori除菌治療 (特集 H.pyloriと胃癌の基礎と臨床)
Related Links
- Intestinal metaplasia is the transformation (metaplasia) of epithelium, usually of the stomach or the esophagus , to a type that bears some resemblance to the intestine as seen in Barrett's esophagus. Chronic infection caused by H. pylori ...
- 1 Jul 2010 ... Intestinal metaplasia (IM) of the gastric mucosa is a relatively frequent precancerous lesion (1). The inclusion of IM in a gastric biopsy pathology report often creates uncertainty for the gastroenterologist about the appropriate ...
Related Pictures
★リンクテーブル★
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- 英
- intestinal metaplasia
- 関
- 化生、胃腺、消化器系#上皮の移行
- Stomach intestinal_metaplasia_CBT_QB_vol2.jpg:胞体が白く抜けているのが杯細胞。腺の基底には赤色で染まるパネート細胞が存在する。
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- 関
- alimentary system、bowel、digestive system、enteric、enteric canal、entero、gastrointestinal、gastrointestinal system、GI、gut、intestinal tract、intestine
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- Reversible change in which one adult cell type (epithelial or mesenchymal) is replaced by another adult cell type