新生児低血糖症
WordNet
- abnormally low blood sugar usually resulting from excessive insulin or a poor diet (同)hypoglycaemia
PrepTutorEJDIC
- 低血糖症,血糖減少症
UpToDate Contents
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English Journal
- Association of adiponectin gene polymorphism 45TG with gestational diabetes mellitus diagnosed on the new IADPSG criteria, plasma adiponectin levels and adverse pregnancy outcomes.
- Han Y1, Zheng YL, Fan YP, Liu MH, Lu XY, Tao Q.
- Clinical and experimental medicine.Clin Exp Med.2015 Feb;15(1):47-53. doi: 10.1007/s10238-014-0275-8. Epub 2014 Mar 25.
- The aim of this study was to identify the association of adiponectin gene single nucleotide polymorphism (SNP) 45TG with gestational diabetes mellitus (GDM) diagnosed on the new International Diabetes in Pregnancy Consensus Group (IADPSG) criteria, plasma adiponectin levels and adverse pregnancy out
- PMID 24664457
- Risk factors for intraventricular hemorrhage in term asphyxiated newborns treated with hypothermia.
- Al Yazidi G1, Srour M1, Wintermark P2.
- Pediatric neurology.Pediatr Neurol.2014 Jun;50(6):630-5. doi: 10.1016/j.pediatrneurol.2014.01.054. Epub 2014 Feb 10.
- BACKGROUND: Intraventricular hemorrhage is rare in term newborns. Severe asphyxia is recognized as one of the risk factors of intraventricular hemorrhage in these newborns. Therapeutic hypothermia, which is the only available treatment for the limitation of brain injury in term asphyxiated newborns,
- PMID 24731482
- A systematic review of risk factors for cerebral palsy in children born at term in developed countries.
- McIntyre S1, Taitz D, Keogh J, Goldsmith S, Badawi N, Blair E.
- Developmental medicine and child neurology.Dev Med Child Neurol.2013 Jun;55(6):499-508. doi: 10.1111/dmcn.12017. Epub 2012 Nov 26.
- AIM: The aim of this study was to conduct a systematic review in order to identify the risk factors for cerebral palsy (CP) in children born at term. The secondary aim was to ascertain if the potential for prevention of these risk factors has been adequately explored.METHOD: A MEDLINE search up to 3
- PMID 23181910
Related Links
- Asphyxia Neonatorum / complications Humans Hyperinsulinism / etiology Hypoglycemia / diagnosis
- Prevalence of neonatal hypoglycemia was 0.4% (52 newborns). Underlying causes of hypoglycemia were prematurity (61.5%), diabetic mother (13.6%), septicemia (9.6%), perinatal asphyxia (9.6%), stress (3.8%) and neonatal hyperinsulinism (1.9%). The mortality rate was 53.8%, with prematurity as the leading cause of death.
- Neonatal hyperinsulinemic hypoglycemia must be suddenly and appropriately diagnosed and treated to prevent any further neurological dysfunction and damage. Therefore, we report two cases of our observation. Case 1: birth asphyxia, episodes of hypoglycemia after delivery, hyperinsulinism and reduced IGFBP1 blood concentration.
★リンクテーブル★
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- 英
- neonatal hypoglycemia, hypoglycemia of the newborn
- ラ
- hypoglycemia neonatorum
概念
- 新生児の血糖値が下記にあてはまる場合。
- 生後72時間以内：低出生体重児で20mg/dl以下、成熟児で30mg/dl以下
- 72時間以後 ：体重に関係なく40mg/dl以下
- 正常な児では出生直後に血糖値80-100mg/dlを示す。
- 臨床的には全血血糖値が40mg/dL未満で処置を開始。最近は60mg/dL未満で治療を開始する施設もある。
原因
- SPE.127
-
症状
- SPE.128
- けいれん、易刺激性(振戦)、異常啼泣(甲高い鳴き声 high-pitched cry)、嗜眠、筋緊張低下、哺乳力低下、嘔吐、無呼吸発作、チアノーゼ、活動性低下、徐脈、心停止
- → 成人で見られる頻脈とか発汗は見られないみたい。自律神経が十分に発達していないせい？
- ↑
- ｜-矛盾している？
- ↓
- SPE.210
- 定義：血糖40mg/dLの児(SPE.210)。(成熟新生児)生後72時間以内30mg/dL以下、以降40mg/dL以下(QB.O-105)。
- 血糖40mg/dLの児を治療対象。40-50mg/dLは要注意 (SPE.210)
- 症状：初期には交感神経亢進による症状(不安、苦悶、発汗、心悸亢進、顔面蒼白、振戦、脱力、空腹感、嘔気・嘔吐)、進行すると中枢神経症状(頭痛、めまい、視力障害、複視、構音障害、失語症、健忘症、集中力低下、運動失調、片麻痺、知覚障害、傾眠、嗜眠、昏睡、除脳硬直) (SPE.210)
脈拍数について
- 参考1に記載無し。
参考
- 1. [charged]Neonatal hypoglycemia - uptodate[1]