WordNet

almost not; "he hardly ever goes fishing"; "he was hardly more than sixteen years old"; "they scarcely ever used the emergency generator" (同)scarcely
very few; "hardly a man is now alive who remembers that famous date and year"
with pain or distress or bitterness; "he took the rejection very hard"
(of light) transmitted directly from a pointed light source (同)concentrated
with firmness; "held hard to the railing" (同)firmly
very strong or vigorous; "strong winds"; "a hard left to the chin"; "a knockout punch"; "a severe blow" (同)knockout, severe
causing great damage or hardship; "industries hit hard by the depression"; "she was severely affected by the banks failure" (同)severely
being distilled rather than fermented; having a high alcoholic content; "hard liquor" (同)strong
unfortunate or hard to bear; "had hard luck"; "a tough break" (同)tough
(of speech sounds); produced with the back of the tongue raised toward or touching the velum; "Russian distinguished between hard consonants and palatalized or soft consonants"
dispassionate; "took a hard look"; "a hard bargainer";
dried out; "hard dry rolls left over from the day before"
earnestly or intently; "thought hard about it"; "stared hard at the accused"
into a solid condition; "concrete that sets hard within a few hours"
resisting weight or pressure
slowly and with difficulty; "prejudices die hard"
to the full extent possible; all the way; "hard alee"; "the ship went hard astern"; "swung the wheel hard left"
very near or close in space or time; "it stands hard by the railroad tracks"; "they were hard on his heels"; "a strike followed hard upon the plants opening"
with effort or force or vigor; "the team played hard"; "worked hard all day"; "pressed hard on the lever"; "hit the ball hard"; "slammed the door hard"

PrepTutorEJDIC

『ほとんど』…『ない』,おそらく…ない;《遠回しに》少しも(全く)…ない
『ほとんど』…『ない』 / 『かろうじて』,やっと(barely) / 《not の遠回しな表現として》まさか(とうてい,おそらく)…ない
(物体が)『堅い』,(手触りが)堅固な,しっかりした / 『難しい』,努力を要する / 《名詞の前にのみ用いて》(人が)『精力的な』,勤勉な / 激しい,猛烈な / (生活などが)耐え難い,つらい / (季節・天候などが)厳しい;(雨・風などが)激しい / (人が)厳格な;(行為などが)容赦しない,無情な / (方針・条件などが)妥協(譲歩)しない,厳しい / (感情が)うらみを含む,憤然とした / (体が)筋肉質の,がんじょうな / (紙幣に対して)硬貨の,(小切手などに対して)現金の;(貨幣が)容易に兌換(だかん)できる / (子音が)硬音の(c,gがcome, goのように[k],[g]と発音される) / アルコール分の多い / (水が)硬質の / (エックス線が)透過能力が大きい / 一生懸命に,『熱心に』 / 『強く』,激しく,大いに / やっと,かろうじて / 『堅く』 / ひどく悲んで / 接近して

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English Journal

Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion.

Rashid R1, Kim DW1, Din FU1, Mustapha O1, Yousaf AM1, Park JH1, Kim JO2, Yong CS3, Choi HG4.
Carbohydrate polymers.Carbohydr Polym.2015 Oct 5;130:26-31. doi: 10.1016/j.carbpol.2015.04.071. Epub 2015 May 12.
The purpose of this research was to evaluate the effect of the HPC (hydroxypropylcellulose) and Tween 80 on the physicochemical properties and oral bioavailability of ezetimibe-loaded solid dispersions. The binary solid dispersions were prepared with drug and various amounts of HPC. Likewise, ternar
PMID 26076597

Smart design of fiber optic surfaces for improved plasmonic biosensing.

Arghir I1, Delport F1, Spasic D1, Lammertyn J2.
New biotechnology.N Biotechnol.2015 Sep 25;32(5):473-484. doi: 10.1016/j.nbt.2015.03.012. Epub 2015 Apr 6.
Although the phenomenon of surface plasmon resonance (SPR) is known for more than a century now, traditional prism-based SPR platforms have hardly escaped the research laboratories despite being recognized for the sensitive and specific performance. Significant efforts have been made over the last y
PMID 25858811

Purification and characterization of a novel antibacterial peptide from black soldier fly (Hermetia illucens) larvae.

Park SI1, Kim JW2, Yoe SM3.
Developmental and comparative immunology.Dev Comp Immunol.2015 Sep;52(1):98-106. doi: 10.1016/j.dci.2015.04.018. Epub 2015 May 5.
In this study, we induced and purified a novel antimicrobial peptide exhibiting activity against Gram-positive bacteria from the immunized hemolymph of Hermetia illucens larvae. The immunized hemolymph was extracted, and the novel defensin-like peptide 4 (DLP4) was purified using solid-phase extract
PMID 25956195

Effect of operational conditions on sonoluminescence and kinetics of H2O2 formation during the sonolysis of water in the presence of Ar/O2 gas mixture.

Pflieger R1, Chave T1, Vite G1, Jouve L1, Nikitenko SI2.
Ultrasonics sonochemistry.Ultrason Sonochem.2015 Sep;26:169-75. doi: 10.1016/j.ultsonch.2015.02.005. Epub 2015 Feb 14.
Ultrasonic frequency is a key parameter determining multibubble sonoluminescence (MBSL) spectra of water saturated with Ar/O2 gas mixtures. At 20kHz, the MBSL is quenched by oxygen. By contrast, at high-frequency ultrasound the maximal MBSL intensity is observed in the presence of Ar/20%O2 gas mixtu
PMID 25703641