haematological disease

血液病

関

blood disease、hematologic disorder、hematological disease

WordNet

1. an impairment of health or a condition of abnormal functioning
2. caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological

PrepTutorEJDIC

1. (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
2. 女性の話術芸人 =diseur
3. 病気にかかった / 病的な,不健全な(morbid)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/02 00:05:23」(JST)

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Hematologic disease
Classification and external resources
MeSH	D006402

Hematologic diseases are disorders which primarily affect the blood. Hematology includes the study of these disorders.

Myeloid

• Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
  • Sickle-cell disease
  • Thalassemia
  • Methemoglobinemia
• Anemias (lack of red blood cells or hemoglobin)
  • Iron deficiency anemia
  • Megaloblastic anemia
    • Vitamin B₁₂ deficiency
      • Pernicious anemia
    • Folate deficiency
  • Hemolytic anemias (destruction of red blood cells)
    • Genetic disorders of RBC membrane
      • Hereditary spherocytosis
      • Hereditary elliptocytosis
      • Congenital dyserythropoietic anemia
    • Genetic disorders of RBC metabolism
      • Glucose-6-phosphate dehydrogenase deficiency (G6PD)
      • Pyruvate kinase deficiency
    • Immune mediated hemolytic anemia (direct Coombs test is positive)
      • Autoimmune hemolytic anemia
        • Warm antibody autoimmune hemolytic anemia
          • Idiopathic
          • Systemic lupus erythematosus (SLE)
          • Evans' syndrome (antiplatelet antibodies and hemolytic antibodies)
        • Cold autoimmune hemolytic anemia
          • Cold agglutinin disease
          • Paroxysmal cold hemoglobinuria (rare)
          • Infectious mononucleosis
      • Alloimmune hemolytic anemia
        • Hemolytic disease of the newborn (HDN)
          • Rh disease (Rh D)
          • ABO hemolytic disease of the newborn
          • Anti-Kell hemolytic disease of the newborn
          • Rhesus c hemolytic disease of the newborn
          • Rhesus E hemolytic disease of the newborn
          • Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
      • Drug induced immune mediated hemolytic anemia
        • Penicillin (high dose)
        • Methyldopa
    • Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
    • Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
    • Direct physical damage to RBCs
      • Microangiopathic hemolytic anemia
      • Secondary to artificial heart valve(s)
  • Aplastic anemia
    • Fanconi anemia
    • Diamond-Blackfan anemia (inherited pure red cell aplasia)
    • Acquired pure red cell aplasia
• Decreased numbers of cells
  • Myelodysplastic syndrome
  • Myelofibrosis
  • Neutropenia (decrease in the number of neutrophils)
  • Agranulocytosis
  • Glanzmann's thrombasthenia
  • Thrombocytopenia (decrease in the number of platelets)
    • Idiopathic thrombocytopenic purpura (ITP)
    • Thrombotic thrombocytopenic purpura (TTP)
    • Heparin-induced thrombocytopenia (HIT)

• Myeloproliferative disorders (Increased numbers of cells)
  • Polycythemia vera (increase in the number of cells in general)
  • Erythrocytosis (increase in the number of red blood cells)
  • Leukocytosis (increase in the number of white blood cells)
  • Thrombocytosis (increase in the number of platelets)
  • Myeloproliferative disorder

• Coagulopathies (disorders of bleeding and coagulation)
  • Thrombocytosis
  • Recurrent thrombosis
  • Disseminated intravascular coagulation
  • Disorders of clotting proteins
    • Hemophilia
      • Hemophilia A
      • Hemophilia B (also known as Christmas disease)
      • Hemophilia C
    • Von Willebrand disease
    • Disseminated intravascular coagulation
    • Protein S deficiency
    • Antiphospholipid syndrome
  • Disorders of platelets
    • Thrombocytopenia
    • Glanzmann's thrombasthenia
    • Wiskott-Aldrich syndrome

Hematological malignancies

• Hematological malignancies
  • Lymphomas
    • Hodgkin's disease
    • Non-Hodgkin's lymphoma{includes the next five entries}
      • Burkitt's lymphoma
      • Anaplastic large cell lymphoma
      • Splenic marginal zone lymphoma
      • Hepatosplenic T-cell lymphoma
      • Angioimmunoblastic T-cell lymphoma (AILT)
  • Myelomas
    • Multiple myeloma
    • Waldenström macroglobulinemia
    • Plasmacytoma
  • Leukemias increased wbc
    • Acute lymphocytic leukemia (ALL)
    • Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
    • Acute myelogenous leukemia (AML)
    • Chronic Idiopathic Myleofibrosis (MF)
    • Chronic myelogenous leukemia (CML)
    • T-cell prolymphocytic leukemia (T-PLL)
    • B-cell prolymphocytic leukemia (B-PLL)
    • Chronic neutrophilic leukemia (CNL)
    • Hairy cell leukemia (HCL)
    • T-cell large granular lymphocyte leukemia (T-LGL)
    • Aggressive NK-cell leukemia

Miscellaneous

• Hemochromatosis
• Asplenia
• Hypersplenism
  • Gaucher's disease
• Monoclonal gammopathy of undetermined significance
• Hemophagocytic lymphohistiocytosis
• Tempi syndrome

Hematological changes secondary to non-hematological disorders

• Anemia of chronic disease
• Infectious mononucleosis
• AIDS
• Malaria
• Leishmaniasis

External links

• http://www.hematologic.niddk.nih.gov/info/index.htm
• Myeloproliferative Disorders (MPD) Foundation and Research Alliance
• International Registry of Rare Bleeding Disorders

UpToDate Contents

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English Journal

• A novel role for thrombopoietin in regulating osteoclast development in humans and mice.

• Bethel M1, Barnes CL2, Taylor AF1, Cheng YH1, Chitteti BR3, Horowitz MC2, Bruzzaniti A4,5, Srour EF3,6,7, Kacena MA1,2,5.
• Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2142-51. doi: 10.1002/jcp.24943.
• Emerging data suggest that megakaryocytes (MKs) play a significant role in skeletal homeostasis. Indeed, osteosclerosis observed in several MK-related disorders may be a result of increased numbers of MKs. In support of this idea, we have previously demonstrated that MKs increase osteoblast (OB) pro
• PMID 25656774

• Salvage therapy with gemcitabine, vinorelbine, and pegylated liposomal doxorubicin for relapsed or refractory pediatric Hodgkin lymphoma. Results of a retrospective series of four children.

• Jaffray M1, Buchbinder N, Lutun A, Schneider P, Piquenot JM, Vannier JP.
• Annals of hematology.Ann Hematol.2015 Aug;94(8):1401-6. doi: 10.1007/s00277-015-2362-7. Epub 2015 Apr 12.
• While the vast majority of pediatric Hodgkin lymphoma (HL) is curable, the prognosis of early relapses and refractory diseases remains poor. Recently, the combination of gemcitabine, vinorelbine, and pegylated liposomal doxorubicin (GVD) displayed encouraging results on adults with relapsed/refracto
• PMID 25862234

• Immunoglobulin D Multiple Myeloma With Rapidly Progressing Renal Failure.

• Modi J1, Kamal J1, Eter A1, El-Sayegh S1, El-Charabaty E1.
• Journal of clinical medicine research.J Clin Med Res.2015 Aug;7(8):653-5. doi: 10.14740/jocmr2210w. Epub 2015 Jun 9.
• Immunoglobulin D (IgD) multiple myeloma (MM) is a very rare form of myeloma affecting less than 2% of all myeloma patients. It has a multiorgan involvement with renal failure being the key feature. We present here a case of IgD MM in a 62-year-old white male, smoker with past medical history of hype
• PMID 26124916

Japanese Journal

• Procalcitonin levels and their predictive effect on mortality in Crimean-Congo Hemorrhagic Fever Patients

• Japanese Journal of Infectious Diseases advpub(0), 2015
• NAID 130005060844

• 咽後膿瘍切開において硬性内視鏡が有用であった1例

• 口腔・咽頭科 25(2), 223-228, 2012
• NAID 130004553149

• 血液疾患における血小板輸血療法 : 適応およびトリガーポイント

• 臨床血液 51(10), 203-210, 2010-10-30
• NAID 10026728423

Related Links

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• Haematological diseases : Latest content : nature.com

Haematological diseases are pathological conditions primarily affecting the blood or blood-producing organs. This group of disorders includes, but is not limited to, various types of anaemia, blood cancers and haemorrhagic conditions.

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★リンクテーブル★

リンク元	「blood disease」「血液病」「hematological disease」「hematologic disorder」
関連記事	「disease」「haematologic」「haematological」

「blood disease」

　　[★]

• 血液病、血液疾患

関

blood disorder、blood dyscrasia、haematological disease、haematological disorder、hematologic disease、hematologic disorder、hematological disease、hematological disorder、hemopathy

「血液病」

　　[★]

英

hematologic disorder、hematological disease、haematological disease、blood disease

関

血液疾患

「hematological disease」

　　[★]

• 血液病

関

blood disease、haematological disease、hematologic disease、hematologic disorder

「hematologic disorder」

　　[★]

血液病

関

blood disease、haematological disease、hematological disease

「disease」

　　[★]

• n.

疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)

特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)

• something that is very wrong with people's attitudes, way of life or with society.

関

ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness

• 注意

disease ≠ illness ≠ disorder

　 　 　

「haematologic」

　　[★]

血液学的な

関

haematological、haematologically、hematologic、hematological、hematologically

「haematological」

　　[★]

血液学的な

関

haematologic、haematologically、hematologic、hematological、hematologically