generalized bullous fixed drug eruption

汎発性水疱性固定薬疹

WordNet

1. set or place definitely; "Lets fix the date for the party!"
2. informal terms for a difficult situation; "he got into a terrible fix"; "he made a muddle of his marriage" (同)hole, jam, mess, muddle, pickle, kettle of fish
3. an exemption granted after influence (e.g., money) is brought to bear; "collusion resulted in tax fixes for gamblers"
4. something craved, especially an intravenous injection of a narcotic drug; "she needed a fix of chocolate"
5. make ready or suitable or equip in advance for a particular purpose or for some use, event, etc; "Get the children ready for school!"; "prepare for war"; "I was fixing to leave town after I paid the hotel bill" (同)prepare, set_up, ready, gear up, set
6. influence an event or its outcome by illegal means; "fix a race"
7. kill, preserve, and harden (tissue) in order to prepare for microscopic study
8. securely placed or fastened or set; "a fixed piece of wood"; "a fixed resistor"
9. incapable of being changed or moved or undone; e.g. "frozen prices"; "living on fixed incomes" (同)frozen
10. fixed and unmoving; "with eyes set in a fixed glassy stare"; "his bearded face already has a set hollow look"- Connor Cruise OBrien; "a face rigid with pain" (同)set, rigid
11. (of a number) having a fixed and unchanging value
12. (of volcanos) pouring out fumes or lava (or a deposit so formed) (同)eructation, extravasation
13. symptom consisting of a breaking out and becoming visible
14. the emergence of a tooth as it breaks through the gum
15. use recreational drugs (同)do drugs
16. administer a drug to; "They drugged the kidnapped tourist" (同)dose
17. a substance that is used as a medicine or narcotic
18. draw from specific cases for more general cases (同)generalise, extrapolate, infer
19. become systemic and spread throughout the body; "this kind of infection generalizes throughout the immune system" (同)generalise
20. speak or write in generalities (同)generalise

PrepTutorEJDIC

1. (…に)…‘を'『固定する』,取り付ける《+『名』+『in』(『on, to』)+『名』》 / …‘を'『決める』,定める / (…に)…‘を'向ける《+『名』+『on』(『upon』)+『名』》 / (…に)…‘を'置く,据える《+『名』+『in』(『on』)+『名』》 / 《米》…‘を'『修理する』,直す / 《話》…‘を'整とんするも,きちんと整える / 〈流行・型など〉‘を'定着させる;〈写真のネガ〉‘を'定着する / 《話》〈試合〉‘を'八百長に仕組む / 《米》〈食事〉‘を'用意する,〈食べ物・飲み物〉‘を'作る / 《俗》…‘に'仕返しする / 《話》苦境,窮地 / (船舶・航空機の)位置の決定 / 《俗》麻薬の注射する;注射する麻薬[の量]
2. 『固定した』,据え付けの / (視線などが)動かない / 確定した,変動しない / 八百長の
3. (病気・災害などの)『突発』,(戦争などの)勃(ぼっ)発;(怒り・笑いの)爆発《+『of』+『名』》 / (溶岩・熱湯などの)『噴出』;(火山の)『噴出』;(火山の)『噴火』《+『of』+『名』》;(火山・間欠泉などからの)噴出物
4. 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/11/07 22:24:04」(JST)

wiki en

[Wiki en表示]

Bullous drug reaction (also known as a "Bullous drug eruption," "Generalized bullous fixed drug eruption," and "Multilocular bullous fixed drug eruption") most commonly refers to a drug reaction in the erythema multiforme group. These are uncommon reactions to medications, with an incidence of 0.4 to 1..2 per million person-years for toxic epidermal necrolysis and 1.2 to 6.0 per million person-years for Stevens–Johnson syndrome. The primary skin lesions are large erythemas (faintly discernible even after confluence), most often irregularly distributed and of a characteristic purplish-livid color, at times with flaccid blisters.

See also

• Skin lesion
• List of cutaneous conditions

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 固定薬疹 fixed drug eruption
• 2. 薬疹 drug eruptions
• 3. 皮膚の水疱を有する患者に対するアプローチ approach to the patient with cutaneous blisters
• 4. 薬物アレルギー：分類および臨床的特徴 drug allergy classification and clinical features
• 5. 従来の癌の化学療法による皮膚合併症 cutaneous complications of conventional chemotherapy agents

English Journal

• [Cutaneous adverse drug reactions.]

• Lebrun-Vignes B1, Valeyrie-Allanore L2.
• La Revue de medecine interne / fondee ... par la Societe nationale francaise de medecine interne.Rev Med Interne.2014 Nov 4. pii: S0248-8663(14)00659-6. doi: 10.1016/j.revmed.2014.10.004. [Epub ahead of print]
• Cutaneous adverse drug reactions (CADR) represent a heterogeneous field including various clinical patterns without specific features suggesting drug causality. Exanthematous eruptions, urticaria and vasculitis are the most common forms of CADR. Fixed eruption is uncommon in western countries. Serio
• PMID 25458866

• Generalized bullous fixed drug eruption is distinct from Stevens-Johnson syndrome/toxic epidermal necrolysis by immunohistopathological features.

• Cho YT1, Lin JW2, Chen YC3, Chang CY1, Hsiao CH4, Chung WH2, Chu CY5.
• Journal of the American Academy of Dermatology.J Am Acad Dermatol.2014 Mar;70(3):539-48. doi: 10.1016/j.jaad.2013.11.015. Epub 2014 Jan 2.
• BACKGROUND: Generalized bullous fixed drug eruption (GBFDE), a particular form of fixed drug eruption (FDE), is characterized by widespread blisters and erosions and can be confused with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).OBJECTIVE: We sought to analyze specific feat
• PMID 24388722

• Flurbiprofen-induced generalized bullous fixed drug eruption.

• Balta I1, Simsek H, Simsek GG.
• Human & experimental toxicology.Hum Exp Toxicol.2014 Jan;33(1):106-8. doi: 10.1177/0960327113489048. Epub 2013 May 23.
• Fixed drug eruption (FDE) is an unusual drug-related side effect that results in recurrent lesions whenever the causative drugs are used. FDEs usually occur as a single, sharply demarcated, round erythematous patch or plaque, occasionally with localized bullae. The most common offending agents inclu
• PMID 23703815

Related Links

• Generalized bullous fixed drug eruption is distinct from ...

1. J Am Acad Dermatol. 2014 Mar;70(3):539-48. doi: 10.1016/j.jaad.2013.11.015. Epub 2014 Jan 2. Generalized bullous fixed drug eruption is distinct from Stevens-Johnson syndrome/toxic epidermal necrolysis by ...

• Prognosis of generalized bullous fixed drug eruption ...

1. Br J Dermatol. 2013 Apr;168(4):726-32. doi: 10.1111/bjd.12133. Epub 2013 Feb 16. Prognosis of generalized bullous fixed drug eruption: comparison with Stevens-Johnson syndrome and toxic epidermal necrolysis. Lipowicz S(1 ...

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★リンクテーブル★

リンク元	「汎発性水疱性固定薬疹」
関連記事	「fix」「eruption」「fixed」「generalize」「generalized」

「汎発性水疱性固定薬疹」

　　[★]

英

generalized bullous fixed drug eruption

関

固定薬疹

「fix」

　　[★]

• v.

• 固定する、修復する

関

clamp、consolidation、fixation、fixed、repair、reparative、restoration、restore、retrieval

　 　 　 　 　 　 　 　

「eruption」

　　[★]

• n.

• (火山の)噴火。(溶岩・間欠泉の)噴出。(医)発疹、皮疹。(歯牙)崩出
• (怒り・笑いなどの)爆発。(病気・戦争などの)突発

関

eruptional

　 　 　 　

「fixed」

　　[★]

• adj.

• 固定された、定型的な

関

clamp、consolidation、fix、fixation、regular、typical

　 　 　 　 　

「generalize」

　　[★]

• v.

• 一般化する、普遍化する、全身性化する

関

generalisation、generalise、generalization

　 　 　

「generalized」

　　[★]

• adj.

• 汎化の、全般的な、全般性の、全身性の

関

generalization、systemic、systemically