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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/15 06:40:31」(JST)

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1. 急性膵炎のマネージメント management of acute pancreatitis
2. 内視鏡的逆行性胆管膵管造影（ERCP）後膵炎 post endoscopic retrograde cholangiopancreatography ercp pancreatitis

Acute Pancreatitis Complicated by Massive Inferior Vena Cava and Right Atrial Thrombosis: A Case Report.

Lee K1, Ko JI1, Park T2.
Annals of vascular surgery.Ann Vasc Surg.2015 Jul;29(5):1020.e7-1020.e10. doi: 10.1016/j.avsg.2015.01.019. Epub 2015 Mar 9.
Venous thrombosis is a relatively common complication of acute pancreatitis. A 58-year-old man came to our emergency department with abdominal pain. Pancreatitis complicated with a huge thrombosis through inferior vena cava (IVC) to right atrium and left renal vein was diagnosed. Gabexate and enoxap
PMID 25765632

Evaluation of Pharmacologic Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Systematic Review.

Kubiliun NM1, Adams MA2, Akshintala VS3, Conte ML4, Cote GA5, Cotton PB6, Dumonceau JM7, Elta GH2, Fogel EL8, Freeman ML9, Lehman GA8, Naveed M1, Romagnuolo J6, Scheiman JM2, Sherman S8, Singh VK3, Elmunzer BJ10; United States Cooperative for Outcomes Research in Endoscopy (USCORE).
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.Clin Gastroenterol Hepatol.2015 Jul;13(7):1231-9. doi: 10.1016/j.cgh.2014.11.038. Epub 2015 Jan 9.
BACKGROUND & AIMS: There is controversy over the efficacy of pharmacologic agents for preventing pancreatitis after endoscopic retrograde cholangiopancreatography (PEP). We performed a systematic review of PEP pharmacoprevention to evaluate safety and efficacy.METHODS: We performed a systematic
PMID 25579870

Combined derivatization and high-performance liquid chromatography with fluorescence and ultraviolet detection for simultaneous analysis of octreotide and gabexate mesylate metabolite in human pancreatic juice samples.

Carlucci G1, Selvaggi F2, Sulpizio S2, Bassi C3, Carlucci M1, Cotellese R2, Ferrone V1, Innocenti P2, Locatelli M1.
Biomedical chromatography : BMC.Biomed Chromatogr.2015 Jun;29(6):911-7. doi: 10.1002/bmc.3373. Epub 2014 Oct 30.
A simple and sensitive method based on the combination of derivatization and high-performance liquid chromatography with ultraviolet and fluorimetric detection was developed for the simultaneous determination of octreotide and gabexate mesylate metabolite in human pancreatic juice samples. Parameter
PMID 25354693

鬼澤俊輔,西野隆義,新井田達雄,山本雅一
東京女子医科大学雑誌 83(6), 400-407, 2013-12-25
ERCP後膵炎(post ERCP pancreatitis: PEP)の予防、治療目的で蛋白分解酵素阻害剤が投与されている.しかし、それら薬剤の低用量でのPEP予防効果については不明な点が少なくない。今回PEP頻度の高い治療的 ERCPを対象とし、ナファモスタットメシル酸塩(NM)の保険収載内の用量でのPEP予防効果を明らかにする目的で、ガベキサートメシル酸塩(GM)と対比し、前向き、二重盲検 …
NAID 110009659604

Telaprevir/Peginterferon/Ribavirin 3剤併用療法施行中に急性膵炎を発症し，Telaprevirの再投与により再燃を来たした1例

松下美紗子,海老沼浩利,福原誠一郎,南和志,南一洋,中本伸宏,船越信介,金井隆典,齋藤英胤,日比紀文
肝臓 54(5), 340-346, 2013
症例は肝細胞癌治療歴のあるC型慢性肝炎の61歳男性．初回治療としてTelaprevir（TPV）・Peginterferon（PEG-IFN）・Ribavirin（RBV）の3剤併用療法を開始後第17病日に急性膵炎を発症した．TPVを中止，PEG-IFN/RBVの投与を継続しつつ，抗生剤・蛋白分解酵素等にて保存的に加療し，改善を認めた．しかし，その後陰性化していたHCV-RNAが陽転したため，十分 …
NAID 130003368686

リンク元	「ガベキサート」
関連記事	「mesilate」

Gabexate
Systematic (IUPAC) name
	ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	39492-01-8
ATC code	None
PubChem	CID: 3447
IUPHAR/BPS	7863
ChemSpider	3329
UNII	4V7M9137X9
KEGG	D08004
ChEMBL	CHEMBL87563
Chemical data
Formula	C16H23N3O4
Molecular mass	311.37 g/mol
	SMILES O=C(Oc1ccc(cc1)C(=O)OCC)CCCCC/N=C(\N)N ;
	InChI InChI=1S/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19) ; Key:YKGYIDJEEQRWQH-UHFFFAOYSA-N ;
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