WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
make complete or perfect; supply what is wanting or form the complement to; "I need some pepper to complement the sweet touch in the soup"
a complete number or quantity; "a full complement"
one of a series of enzymes in the blood serum that are part of the immune response
something added to complete or embellish or make perfect; "a fine wine is a perfect complement to the dinner"; "wild rice was served as an accompaniment to the main dish" (同)accompaniment
number needed to make up a whole force; "a full complement of workers" (同)full complement
a word or phrase used to complete a grammatical construction
either of two parts that mutually complete each other
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
(あるものを完全にするため)(…を)補う物(事)《+『of』+『名』》 / 補語(文法で文の成分の一つ) / (必要な)全数,全量;(船の)定員 / …を補足する,補う
蛋白(たんばく)質

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
2. 補体系の遺伝性疾患 inherited disorders of the complement system
3. 補体系の制御因子および受容体 regulators and receptors of the complement system
4. 補体経路 complement pathways
5. 補体系の後天性疾患 acquired disorders of the complement system

English Journal

Polyclonal and monoclonal antibodies in clinic.

Wootla B, Denic A, Rodriguez M.SourceDepartments of Neurology and Immunology, Mayo Clinic, Rochester, MN, USA.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2014;1060:79-110. doi: 10.1007/978-1-62703-586-6_5.
Immunoglobulins (Ig) or antibodies are heavy plasma proteins, with sugar chains added to amino-acid residues by N-linked glycosylation and occasionally by O-linked glycosylation. The versatility of antibodies is demonstrated by the various functions that they mediate such as neutralization, agglutin
PMID 24037837

Immature mouse granulocytic myeloid cells are characterized by production of ficolin-B.

Weber-Steffens D, Hunold K, Kürschner J, Martinez SG, Elumalai P, Schmidt D, Trevani A, Runza VL, Männel DN.SourceInstitute of Immunology, University of Regensburg, Regensburg, Germany.
Molecular immunology.Mol Immunol.2013 Dec 31;56(4):488-96. doi: 10.1016/j.molimm.2013.06.015. Epub 2013 Aug 1.
Ficolins activate the lectin pathway of the complement system upon binding to carbohydrate patterns on pathogens. To characterize the producer cells of ficolin-B the expression of mouse ficolin-B, the orthologue of human M-ficolin, was studied in macrophages and dendritic cells during differentiatio
PMID 23911405

Toward a structure-based comprehension of the lectin pathway of complement.

Kjaer TR, Thiel S, Andersen GR.SourceDepartment of Biomedicine, Aarhus University, Wilhelm Meyers Allé 4, DK-8000 Aarhus, Denmark.
Molecular immunology.Mol Immunol.2013 Dec 31;56(4):413-22. doi: 10.1016/j.molimm.2013.05.007. Epub 2013 Aug 1.
To initiate the lectin pathway of complement pattern recognition molecules bind to surface-linked carbohydrates or acetyl groups on pathogens or damaged self-tissue. This leads to activation of the serine proteases MASP-1 and MASP-2 resulting in deposition of C4 on the activator and assembly of the
PMID 23911397

Japanese Journal

Anti-Thy-1 Antibody-mediated Complement-dependent Cytotoxicity is Regulated by the Distribution of Antigen, Antibody and Membrane Complement Regulatory Proteins in Rats

Kato Chie,Kato Atsuhiko,Adachi Kenji,Fujii Etsuko,Isobe Kaori,Matsushita Tomochika,Watanabe Takeshi,Suzuki Masami
Journal of Toxicologic Pathology 26(1), 41-49, 2013
… Some therapeutic antibodies as anticancer agents exert their effects through the host immune system, but the factors that predict their cytotoxicity, including complement-dependent cytotoxicity (CDC), are unclear. … The distribution of the Thy-1.1 antigen and 2 membrane complement regulatory proteins (mCRPs), Crry and CD55, in three non-treated animals and the distribution of the injected antibody and C3 in the model was studied by immunohistochemistry. …
NAID 130003362355

Atypical HUS

吉田瑶子,松本雅則,早川正樹,藤村吉博
日本アフェレシス学会雑誌 31(1), 27-32, 2012-02-29
… Recent studies have revealed that aHUS is a disease of complement dysregulation with 50-60% of cases involving the complement regulatory genes, factor H (CFH), membrane cofactor protein (MCP;CD46) and factor I (FI) and so on. … Therefore, it is necessary to establish an appropriate diagnostic pathway focusing on the complement system for choosing the most favorable therapeutic approach in Japan. …
NAID 110009327450

Elevation of Adipsin, a Complement Activating Factor, in the Mouse Placenta During Spontaneous Abortion

Takeshita Ai,Kondo Tomohiro,Okada Toshiya [他],KUSAKABE Ken Takeshi
The Journal of reproduction and development 56(5), 508-514, 2010-10-01
… The complement system is thought to be precisely regulated during pregnancy. … We have examined specific gene profiles in mouse placentas causing spontaneous abortion and found notable up-regulation of adipsin, a complement activating factor. … The aim of the present study was to determine the basic kinetics and localization of adipsin in the placenta and the difference in complement activity between normal placentas and placentas of abortuses. …
NAID 10027571785