カゼインキナーゼIδ
WordNet
- look over, usually with the intention to rob; "They men cased the housed"
- the quantity contained in a case (同)caseful
- a specific state of mind that is temporary; "a case of the jitters"
- (printing) the receptacle in which a compositor has his type, which is divided into compartments for the different letters, spaces, or numbers; "for English, a compositor will ordinarily have two such cases, the upper case containing the capitals and the lower case containing the small letters" (同)compositor''s case, typesetter''s case
- a glass container used to store and display items in a shop or museum or home (同)display case, showcase, vitrine
- bed linen consisting of a cover for a pillow; "the burglar carried his loot in a pillowcase" (同)pillowcase, slip, pillow slip
- a portable container for carrying several objects; "the musicians left their instrument cases backstage"
- nouns or pronouns or adjectives (often marked by inflection) related in some way to other words in a sentence (同)grammatical case
- an occurrence of something; "it was a case of bad judgment"; "another instance occurred yesterday"; "but there is always the famous example of the Smiths" (同)instance, example
- a person requiring professional services; "a typical case was the suburban housewife described by a marriage counselor"
- a problem requiring investigation; "Perry Mason solved the case of the missing heir"
- a statement of facts and reasons used to support an argument; "he stated his case clearly"
- the actual state of things; "that was not the case"
- a milk protein used in making e.g. plastics and adhesives
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
- the basic unit of money in Papua New Guinea
PrepTutorEJDIC
- 〈C〉(…の)『実例』,事例《+『of』+『名』》 / 《the case》『実情』,真相 / 〈C〉〈U〉『場合』,情況,事情,立場 / 〈C〉(…の)(決定すべき)問題,重大事《+『of』+『名』》 / 〈C〉『訴訟』[『事件』],裁判 / 〈C〉(正当な)論拠,弁護;(被告または原告の)主張,申し立て / 〈C〉病状,容態;(症状から見た)患者 / 〈C〉〈U〉格(名詞・代名詞の語形変化)
- (運搬・保管用のいろいろな)『箱』,ケース / (各種の)『容器』,筒,さや,袋,おおい / (標本・陳列用の)ガラス箱,戸だな / (戸・窓などの)わく / 活字箱 / …'を'箱(袋,さやなど)に入れる《+『名』+『up,』+『名』+『up』》
- カゼイン,乾酪素(牛乳の蛋白質;絵具・接着剤にも用いる)
UpToDate Contents
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English Journal
- Casein kinase iδ mutations in familial migraine and advanced sleep phase.
- Brennan KC, Bates EA, Shapiro RE, Zyuzin J, Hallows WC, Huang Y, Lee HY, Jones CR, Fu YH, Charles AC, Ptácek LJ.SourceDepartment of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
- Science translational medicine.Sci Transl Med.2013 May 1;5(183):183ra56. doi: 10.1126/scitranslmed.3005784.
- Migraine is a common disabling disorder with a significant genetic component, characterized by severe headache and often accompanied by nausea, vomiting, and light sensitivity. We identified two families, each with a distinct missense mutation in the gene encoding casein kinase Iδ (CKIδ), in which
- PMID 23636092
- Structural basis for the potent and selective inhibition of casein kinase 1 epsilon.
- Long AM, Zhao H, Huang X.SourceDepartment of Molecular Structure and Characterization, Amgen Inc., 360 Binney Street, Cambridge, Massachusetts 02142, USA.
- Journal of medicinal chemistry.J Med Chem.2012 Nov 26;55(22):10307-11. doi: 10.1021/jm301336n. Epub 2012 Nov 9.
- Casein kinase 1 epsilon (CK1ε) and its closest homologue CK1δ are key regulators of diverse cellular processes. We report two crystal structures of PF4800567, a potent and selective inhibitor of CK1ε, bound to the kinase domains of human CK1ε and CK1δ as well as one apo CK1ε crystal structure.
- PMID 23106386
- An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.
- Matsunaga S, Ikeda M, Kishi T, Fukuo Y, Aleksic B, Yoshimura R, Okochi T, Yamanouchi Y, Kinoshita Y, Kawashima K, Umene-Nakano W, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Nakamura J, Ozaki N, Kitajima T, Iwata N.SourceDepartment of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
- Neuroscience letters.Neurosci Lett.2012 Oct 31;529(1):66-9. doi: 10.1016/j.neulet.2012.08.070. Epub 2012 Sep 7.
- Disturbances of the circadian rhythm are involved in the pathophysiology of bipolar disorder (BD), schizophrenia (SCZ) and major depressive disorder (MDD). Specifically, because clock gene dysfunction is good candidate for enhancing the susceptibility to these psychiatric disorders, we selected two
- PMID 22981886
Related Links
- 1. Mol Cell Biol. 2009 Jul;29(14):3853-66. doi: 10.1128/MCB.00338-09. Epub 2009 May 4. Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Etchegaray JP(1), Machida KK, Noton E, Constance ...
- "Casein Kinase Idelta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are ... A casein kinase I isoenzyme that plays a regulatory role in a variety of ...
★リンクテーブル★
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- 関
- circumstance、event、instance、occasion
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キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase