WordNet

act so as to bring into existence; "effect a change"
a symptom caused by an illness or a drug; "the effects of sleep loss"; "the effect of the anesthetic"
(of a law) having legal validity; "the law is still in effect" (同)force
the central meaning or theme of a speech or literary work (同)essence, burden, core, gist
an impression (especially one that is artificial or contrived); "he just did it for effect"
produce; "The scientists set up a shock wave" (同)effectuate, set_up
property of a personal character that is portable but not used in business; "she left some of her personal effects in the house"; "I watched over their effects until they returned" (同)personal_effects

PrepTutorEJDIC

〈C〉〈U〉『結果』 / 〈C〉〈U〉(…への)『効果』,効きめ,影響《+『on』(『upon』)+『名』》 / 〈C〉(色・音・形などの)印象,感銘 / 《複数形で》品物;身の回り品;動産,財産 / (結果として)…‘を'『もたらす』;〈目的など〉‘を'果たす,遂行する

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1. 妊娠期乳癌：治療 gestational breast cancer treatment
2. 肝疾患を有する患者における化学療法による肝毒性および用量調整 chemotherapy hepatotoxicity and dose modification in patients with liver disease
3. 成人の腎移植における免疫抑制維持療法 maintenance immunosuppressive therapy in renal transplantation in adults
4. 進行性肝細胞癌に対する全身治療 systemic treatment for advanced hepatocellular carcinoma
5. シスプラチン腎障害 cisplatin nephrotoxicity

Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.

Liu Y1, Bi T2, Wang Z1, Wu G1, Qian L1, Gao Q3, Shen G1.
Apoptosis : an international journal on programmed cell death.Apoptosis.2016 Dec;21(12):1398-1407.
Oxymatrine (OMT), one of the main active components of extracts from the dry roots of Sophora flavescens, has been reported to possess many pharmacological properties including cancer-preventive and anti-cancer effects. The aim of the present study is to explore the efficiency of combination therapy
PMID 27671687

RGD peptide targeted lipid-coated nanoparticles for combinatorial delivery of sorafenib and quercetin against hepatocellular carcinoma.

Wang C1, Su L2, Wu C3, Wu J4, Zhu C5, Yuan G5.
Drug development and industrial pharmacy.Drug Dev Ind Pharm.2016 Dec;42(12):1938-1944. Epub 2016 May 20.
CONTEXT: Combination therapies provide a potential solution to address the tumor heterogeneity and drug resistance issues by taking advantage of distinct mechanisms of action of the multiple therapeutics.OBJECTIVE: To design arginine-glycineaspartic acid (RGD) modified lipid-coated nanoparticles (NP
PMID 27142812

Resistance to 3-HTMC-Induced Apoptosis Through Activation of PI3K/Akt, MEK/ERK, and p38/COX-2/PGE2 Pathways in Human HT-29 and HCT116 Colorectal Cancer Cells.

Semaan J1, Pinon A1, Rioux B1, Hassan L1, Limami Y2, Pouget C1, Fagnère C1, Sol V1, Diab-Assaf M3, Simon A1, Liagre B4.
Journal of cellular biochemistry.J Cell Biochem.2016 Dec;117(12):2875-2885. doi: 10.1002/jcb.25600. Epub 2016 May 26.
Increasing incidence and mortality of colorectal cancer brings the necessity to uncover new possibilities in its prevention and treatment. Chalcones have been identified as interesting compounds having chemopreventive and antitumor properties. In this study, we investigated the effects of the synthe
PMID 27192488

Influence of Treatment with Extracts of Hypsyzigus marmoreus Mushroom on Body Composition during Obesity Development in KK-Ay Mice

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Journal of Nutritional Science and Vitaminology 61(1), 96-100, 2015
… Hypsyzigus marmoreus (HM), an edible mushroom, has several effects, including antitumor, antioxidant and anti-allergy properties. … On the other hand, the possibly useful effect of HM in diabetic mice has not as yet been elucidated. …
NAID 130005070827

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Journal of Veterinary Medical Science advpub(0), 2015
… The effect of the antitumor drug, methotrexate (MTX), which is applied to brain tumors, is restricted by the blood-brain barrier (BBB), which is composed of P-glycoprotein (P-gp) and multidrug resistance associated protein (MRP). … In contrast, when MTX was intrathecally administered, CysA had a larger effect on the MTX concentration in the brain than in the CSF. …
NAID 130005067035