αクリスタリンB鎖

WordNet

fasten or secure with chains; "Chain the chairs together"
a unit of length
a necklace made by a stringing objects together; "a string of beads"; "a strand of pearls"; (同)string, strand
a linked or connected series of objects; "a chain of daisies"
a series of (usually metal) rings or links fitted into one another to make a flexible ligament
anything that acts as a restraint
(chemistry) a series of linked atoms (generally in an organic molecule) (同)chemical chain
a series of things depending on each other as if linked together; "the chain of command"; "a complicated concatenation of circumstances" (同)concatenation
(business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership
connect or arrange into a chain by linking
first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
the 2nd letter of the Roman alphabet (同)b
the blood group whose red cells carry the B antigen (同)type_B, group B
British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979) (同)Ernst Boris Chain, Sir Ernst Boris Chain
bound with chains; "enchained demons strained in anger to gnaw on his bones"; "prisoners in chains" (同)enchained

PrepTutorEJDIC

『鎖』;(装飾用の)鎖 / 《複数形で》『束縛』,拘束;囚人をつなぐ鎖 / (物事の)『連続』,つながり《+『of』+『名』》 / (商店・銀行・ホテルなどの)チェーン(一連の店が同一資本のもとで連携して経営される方式;その店) / チェーン(測量で用いられる単位;約21.7m) / …'を'『鎖でつなぐ』《+『up』(『together』)+『名,』+『名』+『up』(『together』)》
アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)

UpToDate Contents

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1. 拡張型心筋症の遺伝学 genetics of dilated cardiomyopathy
2. 心疾患関連する遺伝性症候群 inherited syndromes associated with cardiac disease
3. 炎症性ミオパチーの病因 pathogenesis of inflammatory myopathies
4. アレキサンダー病 alexander disease
5. 特発性拘束性心筋症 idiopathic restrictive cardiomyopathy

English Journal

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin.

Shao W, Zhang SZ, Tang M, Zhang XH, Zhou Z, Yin YQ, Zhou QB, Huang YY, Liu YJ, Wawrousek E, Chen T, Li SB, Xu M, Zhou JN, Hu G, Zhou JW.SourceInstitute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Nature.Nature.2013 Feb 7;494(7435):90-4. doi: 10.1038/nature11748. Epub 2012 Dec 16.
Chronic neuroinflammation is a common feature of the ageing brain and some neurodegenerative disorders. However, the molecular and cellular mechanisms underlying the regulation of innate immunity in the central nervous system remain elusive. Here we show that the astrocytic dopamine D2 receptor (DRD
PMID 23242137

Alpha B-crystallin prevents the arrhythmogenic effects of particulate matter isolated from ambient air by attenuating oxidative stress.

Park H, Park S, Jeon H, Song BW, Kim JB, Kim CS, Pak HN, Hwang KC, Lee MH, Chung JH, Joung B.SourceThe Division of Cardiology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2013 Jan 15;266(2):267-75. doi: 10.1016/j.taap.2012.10.013. Epub 2012 Nov 12.
Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is activated by particulate matter (PM) isolated from ambient air and linked to prolonged repolarization and cardiac arrhythmia. We evaluated whether alpha B-crystallin (CryAB), a heat shock protein, could prevent the arrhythmogenic effects of P
PMID 23153557

Cell penetration peptides for enhanced entry of αB-crystallin into lens cells.

Mueller NH, Ammar DA, Petrash JM.SourceDepartment of Ophthalmology, University of Colorado, School of Medicine, Aurora, CO, USA.
Investigative ophthalmology & visual science.Invest Ophthalmol Vis Sci.2013 Jan 2;54(1):2-8. doi: 10.1167/iovs.12-10947.
PURPOSE: The prevalence of cataract increases with age. Conversely, the abundance of native α-crystallin diminishes with age and cataract development. We hypothesize replenishing lens α-crystallin may delay or prevent cataract. Herein we investigated the ability of cell penetration peptides (CPP)
PMID 23150610